Search Results - "Hashizume, Atsushi"

Disease mechanism, biomarker and therapeutics for spinal and bulbar muscular atrophy (SBMA) by Hashizume, Atsushi, Fischbeck, Kenneth H, Pennuto, Maria, Fratta, Pietro, Katsuno, Masahisa

“…Spinal and bulbar muscular atrophy (SBMA) is a hereditary neuromuscular disorder caused by CAG trinucleotide expansion in the gene encoding the androgen…”
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Preclinical progression of neurodegenerative diseases by Katsuno, Masahisa, Sahashi, Kentaro, Iguchi, Yohei, Hashizume, Atsushi

“…Neurodegenerative diseases are disorders that are characterized by a progressive decline of the motor and/or cognitive function caused by a selective loss of…”
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Association of serum neurofilament light chain levels with clinicopathology of chronic inflammatory demyelinating polyneuropathy, including NF155 reactive patients by Fukami, Yuki, Iijima, Masahiro, Koike, Haruki, Yamada, Shinichiro, Hashizume, Atsushi, Katsuno, Masahisa

“…Objectives To clarify whether serum neurofilament light chains (NfLs) serve as a biomarker of axonal damage in patients with chronic inflammatory demyelinating…”
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Comparing preprocessing strategies for 3D-Gene microarray data of extracellular vesicle-derived miRNAs by Takemoto, Yuto, Ito, Daisuke, Komori, Shota, Kishimoto, Yoshiyuki, Yamada, Shinichiro, Hashizume, Atsushi, Katsuno, Masahisa, Nakatochi, Masahiro

“…Extracellular vesicle-derived (EV)-miRNAs have potential to serve as biomarkers for the diagnosis of various diseases. miRNA microarrays are widely used to…”
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Replacement of Fish Meal by Defatted Yellow Mealworm ( Tenebrio molitor ) Larvae in Diet Improves Growth Performance and Disease Resistance in Red Seabream ( Pargus major ) by Ido, Atsushi, Hashizume, Atsushi, Ohta, Takashi, Takahashi, Takayuki, Miura, Chiemi, Miura, Takeshi

“…Yellow mealworm ( ) larvae are a potential alternative animal protein source for sustainable aquaculture. However, reports on the successful complete…”
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Ratio of urinary N-terminal titin fragment to urinary creatinine is a novel biomarker for amyotrophic lateral sclerosis by Yamada, Shinichiro, Hashizume, Atsushi, Hijikata, Yasuhiro, Ito, Daisuke, Kishimoto, Yoshiyuki, Iida, Madoka, Koike, Haruki, Hirakawa, Akihiro, Katsuno, Masahisa

“…ObjectiveWe aimed to investigate the validity of urinary N-terminal titin fragment as a biomarker for amyotrophic lateral sclerosis (ALS).MethodsWe…”
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Evaluation of Black Soldier Fly ( Hermetia illucens ) Larvae and Pre-Pupae Raised on Household Organic Waste, as Potential Ingredients for Poultry Feed by Kawasaki, Kiyonori, Hashimoto, Yuka, Hori, Akihiro, Kawasaki, Toshiya, Hirayasu, Hirofumi, Iwase, Shun-Ichiro, Hashizume, Atsushi, Ido, Atsushi, Miura, Chiemi, Miura, Takeshi, Nakamura, Satoshi, Seyama, Tomohiro, Matsumoto, Yoshiki, Kasai, Koji, Fujitani, Yasuhiro

“…Black soldier fly (BSF) larvae and pre-pupae could be satisfactorily raised on household organic waste and used as poultry feed, offering a potential…”
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Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study by Inaishi, Takahiro, Takeuchi, Dai, Ichikawa, Takahiro, Inaguma, Gai, Hashizume, Atsushi, Okazaki, Masaki, Masuda, Norikazu, Kikumori, Toyone

“…This study aimed to evaluate the impact of periodic neck ultrasonography (US) on postoperative surveillance for locoregional disease control of patients with…”
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Development of a functional composite for the evaluation of spinal and bulbar muscular atrophy by Inagaki, Tomonori, Hashizume, Atsushi, Hijikata, Yasuhiro, Yamada, Shinichiro, Ito, Daisuke, Kishimoto, Yoshiyuki, Torii, Ryota, Sato, Hiroyuki, Hirakawa, Akihiro, Katsuno, Masahisa

“…This study aimed to develop a functional measurement that combines quantitative motor evaluation index of various body regions in patients with spinal and…”
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Longitudinal analysis of premotor anthropometric and serological markers of Parkinson’s disease by Yokoi, Katsunori, Hattori, Makoto, Satake, Yuki, Tanaka, Yasuhiro, Sato, Maki, Hashizume, Atsushi, Hori, Akihiro, Kawashima, Motoshi, Hirakawa, Akihiro, Watanabe, Hirohisa, Katsuno, Masahisa

“…Parkinson’s disease (PD) is a debilitating neurodegenerative disorder in which nonmotor symptoms, such as constipation and hyposmia, precede the onset of motor…”
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Biomarker-based analysis of preclinical progression in spinal and bulbar muscular atrophy by Hijikata, Yasuhiro, Hashizume, Atsushi, Yamada, Shinichiro, Inagaki, Tomonori, Ito, Daisuke, Hirakawa, Akihiro, Suzuki, Keisuke, Atsuta, Naoki, Tsuboi, Takashi, Hattori, Makoto, Hori, Akihiro, Banno, Haruhiko, Sobue, Gen, Katsuno, Masahisa

“…OBJECTIVETo identify a candidate biomarker reflecting biological changes during the preclinical progression of spinal and bulbar muscular atrophy (SBMA)…”
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TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets by Araki, Kunihiko, Araki, Amane, Honda, Daiyu, Izumoto, Takako, Hashizume, Atsushi, Hijikata, Yasuhiro, Yamada, Shinichiro, Iguchi, Yohei, Hara, Akitoshi, Ikumi, Kazuhiro, Kawai, Kaori, Ishigaki, Shinsuke, Nakamichi, Yoko, Tsunekawa, Shin, Seino, Yusuke, Yamamoto, Akiko, Takayama, Yasunori, Hidaka, Shihomi, Tominaga, Makoto, Ohara-Imaizumi, Mica, Suzuki, Atsushi, Ishiguro, Hiroshi, Enomoto, Atsushi, Yoshida, Mari, Arima, Hiroshi, Muramatsu, Shin-Ichi, Sobue, Gen, Katsuno, Masahisa

“…TAR DNA-binding protein 43 kDa (TDP-43), encoded by TARDBP, is an RNA-binding protein, the nuclear depletion of which is the histopathological hallmark of…”
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Differential target multiplexed spinal cord stimulation using a paddle-type lead placed at the appropriate site for neuropathic pain after spinal cord injury in patients with past spinal surgical histories: study protocol for an exploratory clinical trial by Tanei, Takafumi, Maesawa, Satoshi, Nishimura, Yusuke, Nagashima, Yoshitaka, Ishizaki, Tomotaka, Ando, Masahiko, Kuwatsuka, Yachiyo, Hashizume, Atsushi, Kurasawa, Shimon, Saito, Ryuta

“…Neuropathic pain after spinal cord injury (SCI), both traumatic and non-traumatic, is refractory to various treatments. Spinal cord stimulation (SCS) is one of…”
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Efficacy of the latest new stimulation patterns of spinal cord stimulation for intractable neuropathic pain compared to conventional stimulation: study protocol for a clinical trial by Tanei, Takafumi, Maesawa, Satoshi, Nishimura, Yusuke, Nagashima, Yoshitaka, Ishizaki, Tomotaka, Ando, Masahiko, Kuwatsuka, Yachiyo, Hashizume, Atsushi, Kurasawa, Shimon, Saito, Ryuta

“…Abstract Background Spinal cord stimulation (SCS) is one of the neuromodulation therapies for chronic neuropathic pain. The conventional paresthesia-based SCS…”
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The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity by Ali, Muhammad Fariz Zahir, Yasin, Indri Afriani, Ohta, Takashi, Hashizume, Atsushi, Ido, Atsushi, Takahashi, Takayuki, Miura, Chiemi, Miura, Takeshi

“…We previously identified novel bioactive polysaccharides from Bactrocera cucurbitae and Antheraea yamamai that activate innate immunity in RAW264 murine…”
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The Combined Efficacy of a Two-Year Period of Cybernic Treatment With a Wearable Cyborg Hybrid-Assistive Limb and Leuprorelin Therapy in a Patient With Spinal and Bulbar Muscular Atrophy: A Case Report by Nakatsuji, Hideaki, Ikeda, Tetsuhiko, Hashizume, Atsushi, Katsuno, Masahisa, Sobue, Gen, Nakajima, Takashi

“…Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's disease, is a rare, slowly progressive, incurable, and hereditary neurodegenerative disease…”
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Efficacy confirmation study of aceneuramic acid administration for GNE myopathy in Japan by Mori-Yoshimura, Madoka, Suzuki, Naoki, Katsuno, Masahisa, Takahashi, Masanori P, Yamashita, Satoshi, Oya, Yasushi, Hashizume, Atsushi, Yamada, Shinichiro, Nakamori, Masayuki, Izumi, Rumiko, Kato, Masaaki, Warita, Hitoshi, Tateyama, Maki, Kuroda, Hiroshi, Asada, Ryuta, Yamaguchi, Takuhiro, Nishino, Ichizo, Aoki, Masashi

“…A rare muscle disease, GNE myopathy is caused by mutations in the GNE gene involved in sialic acid biosynthesis. Our recent phase II/III study has indicated…”
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Cardiac and peripheral vasomotor autonomic functions in late-onset transthyretin Val30Met familial amyloid polyneuropathy by Koike, Haruki, Nakamura, Tomohiko, Hashizume, Atsushi, Nishi, Ryoji, Ikeda, Shohei, Kawagashira, Yuichi, Iijima, Masahiro, Katsuno, Masahisa, Sobue, Gen

“…The objective of this study was to systematically investigate cardiac and peripheral vasomotor autonomic functions in late-onset transthyretin Val30Met…”
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Long-term Effects of Androgen Deprivation in a Patient with Spinal and Bulbar Muscular Atrophy - A Case Report with 14 Years of Follow-up by Hijikata, Yasuhiro, Hashizume, Atsushi, Yamada, Shinichiro, Ito, Daisuke, Banno, Haruhiko, Suzuki, Keisuke, Sobue, Gen, Katsuno, Masahisa

“…Spinal and bulbar muscular atrophy (SBMA) is a progressive hereditary neuromuscular disease caused by the testosterone-dependent accumulation of pathogenic…”
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Nasometric Scores in spinal and bulbar muscular atrophy - Effects of palatal lift prosthesis on dysarthria and dysphagia by Tanaka, Seiya, Hashizume, Atsushi, Hijikata, Yasuhiro, Yamada, Shinichiro, Ito, Daisuke, Nakayama, Atsushi, Kurita, Kenichi, Yogo, Hiroaki, Banno, Haruhiko, Suzuki, Keisuke, Yamamoto, Masahiko, Sobue, Gen, Katsuno, Masahisa

“…Spinal and bulbar muscular atrophy (SBMA) is a hereditary neuromuscular disease affecting only males characterized by progressive muscular atrophy and weakness…”
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