Search Results - "Hashimura, Y."

Scale up of allogeneic cell therapy manufacturing in single-use bioreactors: challenges, insights and solutions by Lee, B, Jung, S, Hashimura, Y

“…Background & AimMany allogeneic cell therapy drug candidates are getting closer to commercialization. However, lack of a scalable manufacturing platform to…”
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Scale up of pluripotent stem cell cultivation and directed differentiation in a novel single-use bioreactor system by Lee, B, Hashimura, Y, Jung, S, Wesselschmidt, R

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Scale up of pluripotent stem cell cultivation and differentiation in a novel single-use bioreactor system by Lee, B, Hashimura, Y, Karamil, S, Wesselschmidt, R

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A Systematic Approach for Scale-Down Model Development and Characterization of Commercial Cell Culture Processes by Li, Feng, Hashimura, Yasunori, Pendleton, Robert, Harms, Jean, Collins, Erin, Lee, Brian

“…The objective of process characterization is to demonstrate robustness of manufacturing processes by understanding the relationship between key operating…”
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Scaling a xeno-free fed-batch microcarrier suspension bioreactor system from development to production scale for manufacturing XF hMSCs by Kirian, R.D, Wang, D, Takacs, J, Tsai, A, Cruz, K, Rosello, F, Cox, K, Hashimura, Y, Lembong, J, Rowley, J.A, Jung, S, Ahsan, T

“…Background & AimWith over 800 clinical trials investigating the use of mesenchymal stem/stromal cells (hMSCs) for regenerative medicine, there is an urgent…”
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New Scalable Manufacturing Platform for Shear-Sensitive Cell Therapy Products by Lee, B, Giroux, D, Hashimura, Y, Starkweather, N, Rosello, F, Wesselschmidt, R, Croughan, M

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270 - Scale up of pluripotent stem cell cultivation and directed differentiation in a novel single-use bioreactor system by Lee, B., Hashimura, Y., Jung, S., Wesselschmidt, R.

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178 - Scale up of pluripotent stem cell cultivation and differentiation in a novel single-use bioreactor system by Lee, B., Hashimura, Y., Karamil, S., Wesselschmidt, R.

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244 - New Scalable Manufacturing Platform for Shear-Sensitive Cell Therapy Products by Lee, B., Giroux, D., Hashimura, Y., Starkweather, N., Rosello, F., Wesselschmidt, R., Croughan, M.

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Florence Nightingale: her personality, her life. Importance of observation of "not doing well" by Hashimura, Y

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Metabolism of a new cardiotonic agent, (-)-alpha-(3,4-dimethoxyphenethylaminomethyl)-4-hydroxybenzyl alcohol (TA-064), in man. O-demethylation and ring hydroxylation by Suzuki, T, Hashimura, Y, Takeyama, S

“…A method is described for the determination of plasma concentration of (-)-alpha-(3,4-dimethoxyphenethylaminomethyl)-4-hydroxybenzyl alcohol (TA-064), a new,…”
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In vitro metabolism of the new cardiotonic agent denopamine (TA-064) by rat and rabbit liver preparations. Oxidation, methylation, and glucuronidation by Suzuki, T, Hashimura, Y, Takeyama, S

“…The metabolic pathways of the cardiotonic agent denopamine, (-)-(R)-1-(p-hydroxyphenyl)-2-[(3,4-dimethoxyphenethyl)amino]ethanol, were studied in vitro with…”
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Genetic diseases and molecular genetics

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Acid-base/Na, K, Cl. Experimental and clinical

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Phosphate and pepsin adsorptions by a new boehmite compound and aluminum hydroxide by Nishida, M, Yoshimura, Y, Kawada, J, Ookubo, A, Kagawa, T, Ikawa, A, Hashimura, Y, Suzuki, T

“…A new microcrystalline compound of aluminum oxide hydroxide (tentatively named PT-A) was synthesized in the hope of providing a better phosphate adsorbent for…”
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Antioxidative property of T-0970, a new ureidophenol derivative by Suzumura, K, Hashimura, Y, Kubota, H, Ohmizu, H, Suzuki, T

“…We investigated the antioxidative property of T-0970, a newly synthesized ureidophenol derivative. The inhibitory effect of T-0970 on spontaneous lipid…”
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Quantitative Structure–Activity Analyses of Novel Hydroxyphenylurea Derivatives as Antioxidants by Nakao, Kazuya, Shimizu, Ryo, Kubota, Hitoshi, Yasuhara, Mikiko, Hashimura, Yoshimasa, Suzuki, Toshikazu, Fujita, Toshio, Ohmizu, Hiroshi

“…A series of substituted hydroxyphenylureas was synthesized, the chemical structure of which was designed based on structures of natural antioxidants, vitamin E…”
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Polymerization and conformation of N-carboxy anhydrides of a L-glutamic acid derivative in monolayer by Shibata, Akira, Hashimura, Yuko, Yamashita, Shinsuke, Ueno, Satoru, Yamashita, Takuya

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Mechanism of phosphate adsorption to a three-dimensional structure of boehmite in the presence of bovine serum albumin by Ookubo, A, Nishida, M, Ooi, K, Ishida, K, Hashimura, Y, Ikawa, A, Yoshimura, Y, Kawada, J

“…A new microcrystalline boehmite (tentatively named PT-A) was synthesized as an efficient phosphate adsorbent to replace aluminum hydroxide gel. The…”
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Interaction of bovine serum albumin with the surface of a microcrystalline aluminum oxide hydroxide compound: a possible new type of phosphate adsorbent by Nishida, M, Ookubo, A, Hashimura, Y, Ikawa, A, Yoshimura, Y, Ooi, K, Suzuki, T, Tomita, Y, Kawada, J

“…Aluminum hydroxide gel (ALG) has been effective for ameliorating acidosis associated with phosphatemia caused by hemodialysis. However, aluminum accumulation…”
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