Search Results - "Hashimoto, Mitsumasa"

Machine learning-based prediction of conversion coefficients for I-123 metaiodobenzylguanidine heart-to-mediastinum ratio by Okuda, Koichi, Nakajima, Kenichi, Kitamura, Chiemi, Ljungberg, Michael, Hosoya, Tetsuo, Kirihara, Yumiko, Hashimoto, Mitsumasa

“…We developed a method of standardizing the heart-to-mediastinal ratio in 123I-labeled meta-iodobenzylguanidine (MIBG) images using a conversion coefficient…”
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Calibrated scintigraphic imaging procedures improve quantitative assessment of the cardiac sympathetic nerve activity by Okuda, Koichi, Nakajima, Kenichi, Kitamura, Chiemi, Kirihara, Yumiko, Hashimoto, Mitsumasa, Kinuya, Seigo

“…The 123 I-labeled meta-iodobenzylguanidine (MIBG) is an analogue of noradrenaline that can evaluate cardiac sympathetic activity in scintigraphy. Quantitative…”
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Aquarius is required for proper CtIP expression and homologous recombination repair by Sakasai, Ryo, Isono, Mayu, Wakasugi, Mitsuo, Hashimoto, Mitsumasa, Sunatani, Yumi, Matsui, Tadashi, Shibata, Atsushi, Matsunaga, Tsukasa, Iwabuchi, Kuniyoshi

“…Accumulating evidence indicates that transcription is closely related to DNA damage formation and that the loss of RNA biogenesis factors causes genome…”
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Beads phantom for evaluating heterogeneity of SUV on 18F-FDG PET images by Okuda, Koichi, Saito, Hisahiro, Yamashita, Shozo, Yamamoto, Haruki, Ichikawa, Hajime, Kato, Toyohiro, Yokoyama, Kunihiko, Doai, Mariko, Hashimoto, Mitsumasa, Matoba, Munetaka

“…Purpose This study aimed to develop a dedicated phantom using acrylic beads for texture analysis and to represent heterogeneous 18 F-fluorodeoxyglucose (FDG)…”
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Depletion of RNA-binding protein RBM8A (Y14) causes cell cycle deficiency and apoptosis in human cells by Ishigaki, Yasuhito, Nakamura, Yuka, Tatsuno, Takanori, Hashimoto, Mitsumasa, Shimasaki, Takeo, Iwabuchi, Kuniyoshi, Tomosugi, Naohisa

“…RBM8A (Y14) contains an RNA-binding motif and forms a tight heterodimer with Magoh. The heterodimer is known to be a member of the exon junction complex that…”
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DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair by Kurosawa, Aya, Saito, Shinta, So, Sairei, Hashimoto, Mitsumasa, Iwabuchi, Kuniyoshi, Watabe, Haruka, Adachi, Noritaka

“…Nonhomologous end-joining (NHEJ) and homologous recombination (HR) are two major pathways for repairing DNA double-strand breaks (DSBs); however, their…”
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Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase by Sunatani, Yumi, Kamdar, Radhika Pankaj, Sharma, Mukesh Kumar, Matsui, Tadashi, Sakasai, Ryo, Hashimoto, Mitsumasa, Ishigaki, Yasuhito, Matsumoto, Yoshihisa, Iwabuchi, Kuniyoshi

“…X-ray repair cross-complementing group 4 (XRCC4), a repair protein for DNA double-strand breaks, is cleaved by caspases during apoptosis. In this study, we…”
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Comparison of diagnostic performance of four software packages for phase dyssynchrony analysis in gated myocardial perfusion SPECT by Okuda, Koichi, Nakajima, Kenichi, Matsuo, Shinro, Kashiwaya, Soichiro, Yoneyama, Hiroto, Shibutani, Takayuki, Onoguchi, Masahisa, Hashimoto, Mitsumasa, Kinuya, Seigo

“…Background Phase analysis of gated myocardial perfusion single-photon emission computed tomography (SPECT) for assessment of left ventricular (LV) dyssynchrony…”
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Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells by Takata, Minoru, Sasaki, Masao S., Sonoda, Eiichiro, Morrison, Ciaran, Hashimoto, Mitsumasa, Utsumi, Hiroshi, Yamaguchi-Iwai, Yuko, Shinohara, Akira, Takeda, Shunichi

“…Eukaryotic cells repair DNA double‐strand breaks (DSBs) by at least two pathways, homologous recombination (HR) and non‐homologous end‐joining (NHEJ). Rad54…”
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Development and validation of a direct-comparison method for cardiac 123I-metaiodobenzylguanidine washout rates derived from late 3-hour and 4-hour imaging by Okuda, Koichi, Nakajima, Kenichi, Sugino, Shuichi, Kirihara, Yumiko, Matsuo, Shinro, Taki, Junichi, Hashimoto, Mitsumasa, Kinuya, Seigo

“…Purpose The washout rate (WR) has been used in 123 I-metaiodobenzylguanidine (MIBG) imaging to evaluate cardiac sympathetic innervation. However, WR varies…”
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Optimization of iterative reconstruction parameters with attenuation correction, scatter correction and resolution recovery in myocardial perfusion SPECT/CT by Okuda, Koichi, Nakajima, Kenichi, Yamada, Masato, Wakabayashi, Hiroshi, Ichikawa, Hajime, Arai, Hiroyuki, Matsuo, Shinro, Taki, Junichi, Hashimoto, Mitsumasa, Kinuya, Seigo

“…Objective The aim of this study was to characterize the optimal reconstruction parameters for ordered-subset expectation maximization (OSEM) with attenuation…”
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Induction of centrosome amplification in p53 siRNA‐treated human fibroblast cells by radiation exposure by Kawamura, Kenji, Morita, Nobuyo, Domiki, Chizue, Fujikawa‐Yamamoto, Kozaburo, Hashimoto, Mitsumasa, Iwabuchi, Kuniyoshi, Suzuki, Koji

“…Centrosome amplification can be detected in the tissues of p53−/– mice. In contrast, loss of p53 does not induce centrosome amplification in cultured human…”
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RNA-binding protein RBM8A (Y14) and MAGOH localize to centrosome in human A549 cells by Ishigaki, Yasuhito, Nakamura, Yuka, Tatsuno, Takanori, Hashimoto, Mitsumasa, Iwabuchi, Kuniyoshi, Tomosugi, Naohisa

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Cell sorting analysis of cell cycle-dependent X-ray sensitivity in end joining-deficient human cells by Iwabuchi, Kuniyoshi, Hashimoto, Mitsumasa, Matsui, Tadashi, Kurosawa, Aya, Adachi, Noritaka, Date, Takayasu

“…Non-homologous end joining (NHEJ) plays a major role in the repair of ionizing radiation-induced DNA double-strand breaks (DSBs), especially during the…”
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DNA-PK：the Major Target for Wortmannin-mediated Radiosensitization by the Inhibition of DSB Repair via NHEJ Pathway by Hashimoto, Mitsumasa, Rao, Satish, Tokuno, Osamu, Yamamoto, Ken-Ichi, Takata, Minoru, Takeda, Shunichi, Utsumi, Hiroshi

“…The effect of wortmannin posttreatment was studied in cells derived from different species (hamster, mouse, chicken, and human) with normal and defective…”
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HU Protein of Escherichia coli Has a Role in the Repair of Closely Opposed Lesions in DNA by Hashimoto, Mitsumasa, Imhoff, Barry, Ali, Md Moshi, Kow, Yoke W.

“…Closely opposed lesions form a unique class of DNA damage that is generated by ionizing radiation. Improper repair of closely opposed lesions could lead to the…”
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A case of necrotizing fasciitis developed in a patient with recurrent rectal cancer treated with chemotherapy by Shimada, Ayako, Nakamura, Takeshi, Ishii, Masatsugu, Chiba, Naokazu, Ishikawa, Shuji, Arisawa, Yoshito, Hashimoto, Mitsumasa

“…A fifty-two-year-old female with advanced rectal cancer underwent low anterior resection and hysterectomy. After local pelvic recurrence, she underwent…”
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A Possible Role of Ku in Mediating Sequential Repair of Closely Opposed Lesions by Hashimoto, M, Donald, C D, Yannone, S M, Chen, D J, Roy, R, Kow, Y W

“…One of the hallmarks of ionizing radiation exposure is the formation of clustered damage that includes closely opposed lesions. We show that the Ku70/80…”
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Impact of iterative reconstruction with resolution recovery in myocardial perfusion SPECT: phantom and clinical studies by Okuda, Koichi, Nakajima, Kenichi, Yoneyama, Hiroto, Shibutani, Takayuki, Onoguchi, Masahisa, Matsuo, Shinro, Hashimoto, Mitsumasa, Kinuya, Seigo

“…The corrections of photon attenuation, scatter, and depth-dependent blurring improve image quality in myocardial perfusion single-photon emission computed…”
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UCN-01 (7-hydroxystaurosporine) inhibits the growth of human breast cancer xenografts through disruption of signal transduction by Koh, Junichi, Kubota, Tetsuro, Migita, Tomofusa, Abe, Sadanori, Hashimoto, Mitsumasa, Hosoda, Yoichiro, Kitajima, Masaki

“…7-Hydroxystaurosporine (UCN-01), originally isolated as a phospholipid-dependent protein kinase C inhibitor, has been shown to have antitumor activity against…”
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