Search Results - "Hashikawa, Naoya"
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Lack of alpha CGRP exacerbates the development of atherosclerosis in ApoE-knockout mice
Published in Scientific reports (08-08-2024)“…The effects of calcitonin gene-related peptide (CGRP) on atherosclerosis remain unclear. We used apolipoprotein E-deficient ( ApoE −/− ) mice to generate…”
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2
Effects from the induction of heat shock proteins in a murine model due to progression of aortic atherosclerosis
Published in Scientific reports (29-03-2021)“…Heat shock proteins (HSPs) are molecular chaperones that repair denatured proteins. The relationship between HSPs and various diseases has been extensively…”
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3
Intranasal calcitonin gene-related peptide administration impairs fear memory retention in mice through the PKD/p-HDAC5/Npas4 pathway
Published in Scientific reports (27-01-2022)“…The calcitonin gene-related peptide (CGRP) suppresses fear memory retention in mice. Although intracerebroventricular administration of CGRP alters the fear…”
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4
Npas4 impairs fear memory via phosphorylated HDAC5 induced by CGRP administration in mice
Published in Scientific reports (26-03-2021)“…The relationships among neuropeptide, calcitonin gene-related peptide (CGRP), and memory formation remain unclear. Here, we showed that the…”
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5
Lactobacillus paragasseri OLL2809 Improves Depression-Like Behavior and Increases Beneficial Gut Microbes in Mice
Published in Frontiers in neuroscience (28-06-2022)“…Lactobacillus paragasseri OLL2809 is a probiotic bacterial strain isolated from healthy human feces. While OLL2809 has been studied for its immunomodulatory…”
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6
Roman chamomile inhalation combined with clomipramine treatment improves treatment-resistant depression-like behavior in mice
Published in Biomedicine & pharmacotherapy (01-10-2019)“…•Chronic stress decreases hippocampal NGF but not cytokine and BDNF mRNA levels.•Roman chamomile with clomipramine decreases immobility time in a forced swim…”
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7
CGRP causes anxiety via HP1γ–KLF11–MAOB pathway and dopamine in the dorsal hippocampus
Published in Communications biology (19-03-2024)“…Calcitonin gene-related peptide (CGRP) is a neuropeptide that causes anxiety behavior; however, the underlying mechanisms remain unclear. We found that CGRP…”
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CGRP overexpression does not alter depression-like behavior in mice
Published in PeerJ (San Francisco, CA) (02-07-2021)“…The calcitonin gene-related peptide (CGRP) is a neuropeptide that is released from capsaicin-sensitive nerves as a potent vasodilator involved in nociceptive…”
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9
Effects of alcoholic beverage treatment on spatial learning and fear memory in mice
Published in Bioscience, biotechnology, and biochemistry (03-08-2018)“…Although chronic ethanol treatment is known to impair learning and memory, humans commonly consume a range of alcoholic beverages. However, the specific…”
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Oral administration of Eucommia ulmoides Oliv. leaves extract protects against atherosclerosis by improving macrophage function in ApoE knockout mice
Published in Journal of food science (01-11-2020)“…Eucommia leaf extract (ELE) is a traditional Chinese herbal medicine. We investigated the effect of ELE on the development of atherosclerosis and changes in…”
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11
Calcitonin gene-related peptide pre-administration acts as a novel antidepressant in stressed mice
Published in Scientific reports (07-08-2015)“…Calcitonin gene-related peptide (CGRP) is a neuropeptide that has potent vasodilator properties and is involved in various behavioral disorders. The…”
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12
Candesartan Cilexetil Improves Angiotensin II Type 2 Receptor-Mediated Neurite Outgrowth via the PI3K-Akt Pathway in Fructose-Induced Insulin-Resistant Rats
Published in Diabetes (New York, N.Y.) (01-04-2012)“…We have shown previously that stimulation of the angiotensin II type 2 receptor (AT(2)R) results in nerve facilitation. In this study, we determined the…”
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13
The Mechanism of Calcitonin Gene-Related Peptide–Containing Nerve Innervation
Published in Journal of Pharmacological Sciences (2012)“…Calcitonin gene-related peptide (CGRP) is a major neurotransmitter and CGRP-containing primary sensory neurons play an important role in nociception and potent…”
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14
Different Mechanisms Are Involved in the Transcriptional Activation by Yeast Heat Shock Transcription Factor through Two Different Types of Heat Shock Elements
Published in The Journal of biological chemistry (06-04-2007)“…The hydrophobic repeat is a conserved structural motif of eukaryotic heat shock transcription factor (HSF) that enables HSF to form a homotrimer. Homotrimeric…”
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15
Time Course of Behavioral Alteration and mRNA Levels of Neurotrophic Factor Following Stress Exposure in Mouse
Published in Cellular and molecular neurobiology (01-08-2015)“…Stress is known to affect neurotrophic factor expression, which induces depression-like behavior. However, whether there are time-dependent changes in…”
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Hyperinsulinemia induces hypertension associated with neurogenic vascular dysfunction resulting from abnormal perivascular innervations in rat mesenteric resistance arteries
Published in Hypertension research (01-11-2011)“…We previously reported that chronic hyperinsulinemia and insulin resistance induced by fructose-drinking loading elicited hypertension associated with abnormal…”
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Role of Heat Shock Transcription Factor in Saccharomyces cerevisiae Oxidative Stress Response
Published in Eukaryotic Cell (01-08-2007)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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HSP105 prevents depression-like behavior by increasing hippocampal brain-derived neurotrophic factor levels in mice
Published in Science advances (01-05-2017)“…Heat shock proteins (HSPs) are stress-induced chaperones that are involved in neurological disease. Although increasingly implicated in behavioral disorders,…”
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Phosphorylation of the Yeast Heat Shock Transcription Factor Is Implicated in Gene-Specific Activation Dependent on the Architecture of the Heat Shock Element
Published in Molecular and Cellular Biology (01-05-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Akt-nitric oxide-cGMP pathway contributes to nerve growth factor-mediated neurite outgrowth in apolipoprotein E knockout mice
Published in The Journal of pharmacology and experimental therapeutics (01-08-2011)“…Apolipoprotein E (apo)-deficient [apoE(-/-)] mice have peripheral sensory nerve defects and a reduced and delayed response to noxious thermal stimuli. However,…”
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