Search Results - "Hashikawa, Naoya"

Refine Results
  1. 1

    Lack of alpha CGRP exacerbates the development of atherosclerosis in ApoE-knockout mice by Hashikawa-Hobara, Narumi, Inoue, Shota, Hashikawa, Naoya

    Published in Scientific reports (08-08-2024)
    “…The effects of calcitonin gene-related peptide (CGRP) on atherosclerosis remain unclear. We used apolipoprotein E-deficient ( ApoE −/− ) mice to generate…”
    Get full text
    Journal Article
  2. 2

    Effects from the induction of heat shock proteins in a murine model due to progression of aortic atherosclerosis by Hashikawa, Naoya, Ido, Masanobu, Morita, Yuna, Hashikawa-Hobara, Narumi

    Published in Scientific reports (29-03-2021)
    “…Heat shock proteins (HSPs) are molecular chaperones that repair denatured proteins. The relationship between HSPs and various diseases has been extensively…”
    Get full text
    Journal Article
  3. 3

    Intranasal calcitonin gene-related peptide administration impairs fear memory retention in mice through the PKD/p-HDAC5/Npas4 pathway by Hashikawa-Hobara, Narumi, Yoneyama, Yoshikazu, Fujiwara, Kyoushiro, Hashikawa, Naoya

    Published in Scientific reports (27-01-2022)
    “…The calcitonin gene-related peptide (CGRP) suppresses fear memory retention in mice. Although intracerebroventricular administration of CGRP alters the fear…”
    Get full text
    Journal Article
  4. 4

    Npas4 impairs fear memory via phosphorylated HDAC5 induced by CGRP administration in mice by Hashikawa-Hobara, Narumi, Mishima, Shuta, Okujima, Chihiro, Shitanishi, Youdai, Hashikawa, Naoya

    Published in Scientific reports (26-03-2021)
    “…The relationships among neuropeptide, calcitonin gene-related peptide (CGRP), and memory formation remain unclear. Here, we showed that the…”
    Get full text
    Journal Article
  5. 5

    Lactobacillus paragasseri OLL2809 Improves Depression-Like Behavior and Increases Beneficial Gut Microbes in Mice by Hashikawa-Hobara, Narumi, Otsuka, Ami, Okujima, Chihiro, Hashikawa, Naoya

    Published in Frontiers in neuroscience (28-06-2022)
    “…Lactobacillus paragasseri OLL2809 is a probiotic bacterial strain isolated from healthy human feces. While OLL2809 has been studied for its immunomodulatory…”
    Get full text
    Journal Article
  6. 6

    Roman chamomile inhalation combined with clomipramine treatment improves treatment-resistant depression-like behavior in mice by Hashikawa-Hobara, Narumi, Otsuka, Ami, Ishikawa, Risa, Hashikawa, Naoya

    Published in Biomedicine & pharmacotherapy (01-10-2019)
    “…•Chronic stress decreases hippocampal NGF but not cytokine and BDNF mRNA levels.•Roman chamomile with clomipramine decreases immobility time in a forced swim…”
    Get full text
    Journal Article
  7. 7

    CGRP causes anxiety via HP1γ–KLF11–MAOB pathway and dopamine in the dorsal hippocampus by Hashikawa-Hobara, Narumi, Fujiwara, Kyoshiro, Hashikawa, Naoya

    Published in Communications biology (19-03-2024)
    “…Calcitonin gene-related peptide (CGRP) is a neuropeptide that causes anxiety behavior; however, the underlying mechanisms remain unclear. We found that CGRP…”
    Get full text
    Journal Article
  8. 8

    CGRP overexpression does not alter depression-like behavior in mice by Hashikawa-Hobara, Narumi, Otsuka, Ami, Okujima, Chihiro, Hashikawa, Naoya

    Published in PeerJ (San Francisco, CA) (02-07-2021)
    “…The calcitonin gene-related peptide (CGRP) is a neuropeptide that is released from capsaicin-sensitive nerves as a potent vasodilator involved in nociceptive…”
    Get full text
    Journal Article
  9. 9

    Effects of alcoholic beverage treatment on spatial learning and fear memory in mice by Hashikawa-Hobara, Narumi, Mishima, Shuta, Nagase, Shotaro, Morita, Keishi, Otsuka, Ami, Hashikawa, Naoya

    “…Although chronic ethanol treatment is known to impair learning and memory, humans commonly consume a range of alcoholic beverages. However, the specific…”
    Get full text
    Journal Article
  10. 10

    Oral administration of Eucommia ulmoides Oliv. leaves extract protects against atherosclerosis by improving macrophage function in ApoE knockout mice by Hashikawa‐Hobara, Narumi, Hashikawa, Naoya, Sugiman, Nao, Hosoo, Shingo, Hirata, Tetsuya, Yamaguchi, Yasuyo, Yamasaki, Hiroo, Kawasaki, Hiromu, Nishibe, Sansei

    Published in Journal of food science (01-11-2020)
    “…Eucommia leaf extract (ELE) is a traditional Chinese herbal medicine. We investigated the effect of ELE on the development of atherosclerosis and changes in…”
    Get full text
    Journal Article
  11. 11

    Calcitonin gene-related peptide pre-administration acts as a novel antidepressant in stressed mice by Hashikawa-Hobara, Narumi, Ogawa, Takumi, Sakamoto, Yusuke, Matsuo, Yumi, Ogawa, Mami, Zamami, Yoshito, Hashikawa, Naoya

    Published in Scientific reports (07-08-2015)
    “…Calcitonin gene-related peptide (CGRP) is a neuropeptide that has potent vasodilator properties and is involved in various behavioral disorders. The…”
    Get full text
    Journal Article
  12. 12

    Candesartan Cilexetil Improves Angiotensin II Type 2 Receptor-Mediated Neurite Outgrowth via the PI3K-Akt Pathway in Fructose-Induced Insulin-Resistant Rats by HASHIKAWA-HOBARA, Narumi, HASHIKAWA, Naoya, INOUE, Yusuke, SANDA, Hitomi, ZAMAMI, Yoshito, TAKATORI, Shingo, KAWASAKI, Hiromu

    Published in Diabetes (New York, N.Y.) (01-04-2012)
    “…We have shown previously that stimulation of the angiotensin II type 2 receptor (AT(2)R) results in nerve facilitation. In this study, we determined the…”
    Get full text
    Journal Article
  13. 13

    The Mechanism of Calcitonin Gene-Related Peptide–Containing Nerve Innervation by Hashikawa-Hobara, Narumi, Hashikawa, Naoya, Zamami, Yoshito, Takatori, Shingo, Kawasaki, Hiromu

    “…Calcitonin gene-related peptide (CGRP) is a major neurotransmitter and CGRP-containing primary sensory neurons play an important role in nociception and potent…”
    Get full text
    Journal Article
  14. 14

    Different Mechanisms Are Involved in the Transcriptional Activation by Yeast Heat Shock Transcription Factor through Two Different Types of Heat Shock Elements by Hashikawa, Naoya, Yamamoto, Noritaka, Sakurai, Hiroshi

    Published in The Journal of biological chemistry (06-04-2007)
    “…The hydrophobic repeat is a conserved structural motif of eukaryotic heat shock transcription factor (HSF) that enables HSF to form a homotrimer. Homotrimeric…”
    Get full text
    Journal Article
  15. 15

    Time Course of Behavioral Alteration and mRNA Levels of Neurotrophic Factor Following Stress Exposure in Mouse by Hashikawa, Naoya, Ogawa, Takumi, Sakamoto, Yusuke, Ogawa, Mami, Matsuo, Yumi, Zamami, Yoshito, Hashikawa-Hobara, Narumi

    Published in Cellular and molecular neurobiology (01-08-2015)
    “…Stress is known to affect neurotrophic factor expression, which induces depression-like behavior. However, whether there are time-dependent changes in…”
    Get full text
    Journal Article
  16. 16
  17. 17

    Role of Heat Shock Transcription Factor in Saccharomyces cerevisiae Oxidative Stress Response by Yamamoto, Ayako, Ueda, Junko, Yamamoto, Noritaka, Hashikawa, Naoya, Sakurai, Hiroshi

    Published in Eukaryotic Cell (01-08-2007)
    “…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
    Get full text
    Journal Article
  18. 18

    HSP105 prevents depression-like behavior by increasing hippocampal brain-derived neurotrophic factor levels in mice by Hashikawa, Naoya, Utaka, Yuta, Ogawa, Takumi, Tanoue, Ryo, Morita, Yuna, Yamamoto, Sayumi, Yamaguchi, Satoru, Kayano, Masafumi, Zamami, Yoshito, Hashikawa-Hobara, Narumi

    Published in Science advances (01-05-2017)
    “…Heat shock proteins (HSPs) are stress-induced chaperones that are involved in neurological disease. Although increasingly implicated in behavioral disorders,…”
    Get full text
    Journal Article
  19. 19

    Phosphorylation of the Yeast Heat Shock Transcription Factor Is Implicated in Gene-Specific Activation Dependent on the Architecture of the Heat Shock Element by Hashikawa, Naoya, Sakurai, Hiroshi

    Published in Molecular and Cellular Biology (01-05-2004)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
    Get full text
    Journal Article
  20. 20

    The Akt-nitric oxide-cGMP pathway contributes to nerve growth factor-mediated neurite outgrowth in apolipoprotein E knockout mice by Hashikawa-Hobara, Narumi, Hashikawa, Naoya, Yutani, Chikao, Zamami, Yoshito, Jin, Xin, Takatori, Shingo, Mio, Mitsunobu, Kawasaki, Hiromu

    “…Apolipoprotein E (apo)-deficient [apoE(-/-)] mice have peripheral sensory nerve defects and a reduced and delayed response to noxious thermal stimuli. However,…”
    Get more information
    Journal Article