Search Results - "Hasegawa, Yuto"

Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology? by Hasegawa, Yuto, Ma, Minghong, Sawa, Akira, Lane, Andrew P., Kamiya, Atsushi

“…Olfactory impairments contribute to the psychopathology of mental illnesses such as schizophrenia and depression. Recent neuroscience research has shed light…”
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Inflamed brain: Targeting immune changes and inflammation for treatment of depression by Sakamoto, Shinji, Zhu, Xiaolei, Hasegawa, Yuto, Karma, Sadik, Obayashi, Mizuho, Alway, Emily, Kamiya, Atsushi

“…Although there are a number of clinically effective treatments for depression, many patients exhibit treatment resistance. Recent clinical and preclinical…”
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Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication by Hasegawa, Yuto, Kim, Juhyun, Ursini, Gianluca, Jouroukhin, Yan, Zhu, Xiaolei, Miyahara, Yu, Xiong, Feiyi, Madireddy, Samskruthi, Obayashi, Mizuho, Lutz, Beat, Sawa, Akira, Brown, Solange P., Pletnikov, Mikhail V., Kamiya, Atsushi

“…Adolescent cannabis use increases the risk for cognitive impairments and psychiatric disorders. Cannabinoid receptor type 1 (Cnr1) is expressed not only in…”
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Causal impact of local inflammation in the nasal cavity on higher brain function and cognition by Hasegawa, Yuto, Namkung, Ho, Smith, Amy, Sakamoto, Shinji, Zhu, Xiaolei, Ishizuka, Koko, Lane, Andrew P., Sawa, Akira, Kamiya, Atsushi

“…•Olfactory dysfunction involved in the pathophysiology of neuropsychiatric diseases.•Olfactory epithelium as an entry point for exposure to environmental risk…”
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Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice by Tzeng, Te-Chen, Hasegawa, Yuto, Iguchi, Risa, Cheung, Amy, Caffrey, Daniel R., Thatcher, Elizabeth Jeanne, Mao, Wenjie, Germain, Gail, DePaula Tamburro, Nelsy, Okabe, Shigeo, Heneka, Michael T., Latz, Eicke, Futai, Kensuke, Golenbock, Douglas T.

“…Alzheimer’s disease (AD) is characterized by the progressive destruction and dysfunction of central neurons. AD patients commonly have unprovoked seizures…”
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Variability of photosensitive period and voltinism among populations of a butterfly, Ypthima multistriata, inhabiting similar latitudes and altitudes by Hasegawa, Yuto, Takeuchi, Tsuyoshi, Hirai, Norio

“…In Ypthima multistriata Butler (Lepidoptera: Nymphalidae), there are univoltine and bivoltine populations in adjacent areas with similar climatic conditions. A…”
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In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene by Peter, Cyril J., Saito, Atsushi, Hasegawa, Yuto, Tanaka, Yuya, Nagpal, Mohika, Perez, Gabriel, Alway, Emily, Espeso-Gil, Sergio, Fayyad, Tariq, Ratner, Chana, Dincer, Aslihan, Gupta, Achla, Devi, Lakshmi, Pappas, John G., Lalonde, François M., Butman, John A., Han, Joan C., Akbarian, Schahram, Kamiya, Atsushi

“…Many neuropsychiatric risk genes contribute to epigenetic regulation but little is known about specific chromatin-associated mechanisms governing the formation…”
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Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1 by Mao, Wenjie, Salzberg, Anna C., Uchigashima, Motokazu, Hasegawa, Yuto, Hock, Hanno, Watanabe, Masahiko, Akbarian, Schahram, Kawasawa, Yuka Imamura, Futai, Kensuke

“…Homeostatic synaptic downscaling reduces neuronal excitability by modulating the number of postsynaptic receptors. Histone modifications and the subsequent…”
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A Case of Chronic Isolated Dissecting Aneurysm of Superior Mesenteric Artery by Hasegawa, Yuto, Shintani, Tsunehiro, Natsume, Kayoko, Ohkura, Kazuhiro

“…Isolated dissecting aneurysm of superior mesenteric artery (IDSMA) is a rare entity with limited studies about its treatment. We report a successful surgical…”
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Type B Acute Aortic Dissection as a Perioperative Complication after an Endovascular Abdominal Aortic Repair by Natsume, Kayoko, Shintani, Tsunehiro, Hayahi, Masanori, Ohkura, Kazuhiro, Hasegawa, Yuto, Ariya, Takumi

“…Type B aortic dissection (TBAD) is a rare but catastrophic complication of endovascular aneurysm repair (EVAR). We report two cases of TBAD occurring in the…”
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Ileo-ileal intussusception caused by lymphangioma of the small bowel treated by single-incision laparoscopic-assisted ileal resection by Kohga, Atsushi, Kawabe, Akihiro, Hasegawa, Yuto, Yajima, Kiyoshige, Okumura, Takuya, Yamashita, Kimihiro, Isogaki, Jun, Suzuki, Kenji, Komiyama, Akira

“…Intraabdominal lymphangiomas are uncommon;additionally,those affecting the gastrointestinal tract are rare and account for less than 1%of cases.Intussusception…”
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Correction: JHU-083 selectively blocks glutaminase activity in brain CD11b + cells and prevents depression-associated behaviors induced by chronic social defeat stress by Zhu, Xiaolei, Nedelcovych, Michael T, Thomas, Ajit G, Hasegawa, Yuto, Moreno-Megui, Aisa, Coomer, Wade, Vohra, Varun, Saito, Atsushi, Perez, Gabriel, Wu, Ying, Alt, Jesse, Prchalova, Eva, Tenora, Lukáš, Majer, Pavel, Rais, Rana, Rojas, Camilo, Slusher, Barbara S, Kamiya, Atsushi

“…During this process, we found that we need add the following sentence in the manuscript within the Acknowledgement section…”
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Effect of Atheromatous Aorta on Thromboembolic Complications after Endovascular Aortic Aneurysm by Shintani, Tsunehiro, Mitsuoka, Hiroshi, Hasegawa, Yuto, Hayashi, Masanori, Natsume, Kayoko, Ookura, Kazuhiro, Sato, Yasunori, Obara, Hideaki

“…Objective: The purpose of this study was to evaluate the effect of atheromatous aorta on thromboembolic complications after endovascular aortic aneurysm repair…”
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Glutamine antagonist JHU083 improves psychosocial behavior and sleep deficits in EcoHIV-infected mice by Bell, Benjamin J., Hollinger, Kristen R., Deme, Pragney, Sakamoto, Shinji, Hasegawa, Yuto, Volsky, David, Kamiya, Atsushi, Haughey, Norman, Zhu, Xiaolei, Slusher, Barbara S.

“…Combined antiretroviral therapy ushered an era of survivable HIV infection in which people living with HIV (PLH) conduct normal life activities and enjoy…”
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Luciferase shRNA Presents off-Target Effects on Voltage-Gated Ion Channels in Mouse Hippocampal Pyramidal Neurons by Hasegawa, Yuto, Mao, Wenjie, Saha, Sucharita, Gunner, Georgia, Kolpakova, Jenya, Martin, Gilles E, Futai, Kensuke

“…RNA interference (RNAi) is a straightforward approach to study gene function from the cellular level to animal behavior. Although RNAi-mediated gene knockdown…”
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Torsion of Atypical Meckel’s Diverticulum Treated by Laparoscopic-Assisted Surgery by Komiyama, Akira, Kawabe, Akihiro, Isogaki, Jun, Okumura, Takuya, Yajima, Kiyoshige, Hasegawa, Yuto, Yamashita, Kimihiro, Kohga, Atsushi, Suzuki, Kenji

“…Introduction. Meckel’s diverticulum (MD) is the most common congenital anomaly of the intestine, with an incidence of 2~4%. Of those, only 2% of patients with…”
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偶発的に発見された慢性孤立性上腸間膜動脈解離性動脈瘤に対する1手術例 by 長谷川, 悠人, 新谷, 恒弘, 夏目, 佳代子, 大倉, 一宏

“…症例は60代男性．偶発的に30 mmの上腸間膜動脈瘤を指摘された．上腸間膜動脈の大動脈起始部から25…”
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NV-5138 as a fast-acting antidepressant via direct activation of mTORC1 signaling by Hasegawa, Yuto, Zhu, Xiaolei, Kamiya, Atsushi

“…Growing evidence implicates altered mTORC1 signaling cascades in the pathophysiology of depression, suggesting that direct modulation of mTORC1 signaling may…”
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Activation of protein kinase R in the manganese-induced apoptosis of PC12 cells by Yagyu, Kazuya, Hasegawa, Yuto, Sato, Mina, Oh-hashi, Kentaro, Hirata, Yoko

“…•The PKR inhibitor C16 strongly prevents manganese-inducedapoptosis in PC12 cells.•Manganese induces the proteolytic activation of PKR in PC12 cells.•The…”
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Dectin-1 signaling on colonic γδ T cells promotes psychosocial stress responses by Zhu, Xiaolei, Sakamoto, Shinji, Ishii, Chiharu, Smith, Matthew D., Ito, Koki, Obayashi, Mizuho, Unger, Lisa, Hasegawa, Yuto, Kurokawa, Shunya, Kishimoto, Taishiro, Li, Hui, Hatano, Shinya, Wang, Tza-Huei, Yoshikai, Yasunobu, Kano, Shin-ichi, Fukuda, Shinji, Sanada, Kenji, Calabresi, Peter A., Kamiya, Atsushi

“…The intestinal immune system interacts with commensal microbiota to maintain gut homeostasis. Furthermore, stress alters the microbiome composition, leading to…”
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