Search Results - "Hasegawa, Sho"
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Urinary single-cell transcriptomics: a promising noninvasive method for assessing acute kidney injury
Published in Kidney international (01-12-2022)“…Noninvasive methods for obtaining intrarenal information are required to understand the mechanism of acute kidney injury (AKI). Klocke et al. explored the…”
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SGLT2 inhibition in chronic kidney disease: a preventive strategy against acute kidney injury at the same time?
Published in Kidney international (01-01-2022)“…Sodium-glucose co-transporter 2 (SGLT2) inhibitors are known to slow down progression of chronic kidney disease. However, theoretical concerns still exist that…”
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Harnessing Metabolomics to Describe the Pathophysiology Underlying Progression in Diabetic Kidney Disease
Published in Current diabetes reports (01-07-2021)“…Purpose of Review Diabetic kidney disease (DKD), a leading cause of end-stage kidney disease, is the result of metabolic network alterations in the kidney…”
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The subtle long-lasting burden of mitochondrial DNA variants
Published in Nature reviews. Nephrology (01-01-2022)“…A new study reports that common mitochondrial DNA variants in specific haplogroups induce metabolic alterations that affect the onset of common age-related…”
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Hypoxia-inducible factor stabilizers for treating anemia of chronic kidney disease
Published in Current opinion in nephrology and hypertension (01-09-2018)“…PURPOSE OF REVIEWSmall-molecule inhibitors of prolyl hydroxylase domain enzymes (PHD inhibitors) are novel renal anemia therapies that increase endogenous…”
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Bismuth induced enhancement of Rashba spin–orbit interaction in GaAsBi/GaAs heterostructures
Published in Applied physics letters (01-05-2023)“…The incorporation of heavy atoms into semiconductor heterostructures is a promising way to enhance the spin–orbit interaction of carriers moving in…”
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Plastic or self‐expandable metal stent: Which is the most suitable for patients with pancreatic head cancer in the upcoming era of neoadjuvant chemotherapy? A review
Published in Digestive endoscopy (01-01-2022)“…Obstructive jaundice is a major symptom of pancreatic head cancer, and although its amelioration is required before scheduling chemotherapy, the decision to…”
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The Efficacy of Combined Use of Pertuzumab and Trastuzumab-Based Neoadjuvant Chemotherapy for HER2 Positive Breast Cancer
Published in Gan to kagaku ryoho (01-12-2021)“…NeoSphere trial showed that combined use of pertuzumab and trastuzumab-based chemotherapy for HER2 positive breast cancer improved the rate of pathological…”
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Organelle Stress and Crosstalk in Kidney Disease
Published in Kidney360 (29-10-2020)“…Organelles play important roles in maintaining cellular homeostasis. Organelle stress responses, especially in mitochondria, endoplasmic reticula (ER), and…”
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Effects of discontinuation of antihypertensive drugs on frailty syndrome in outpatients: a 1-year prospectively designed retrospective chart-review pilot study
Published in Journal of international medical research (01-10-2022)“…Objective To investigate the effects of discontinuing antihypertensive drugs on the characteristics of patients with frailty syndrome. Methods This prospective…”
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Raman scattering study of photoexcited plasma in GaAsBi/GaAs heterostructures: Influence of carrier confinement on photoluminescence
Published in Materials science in semiconductor processing (01-08-2023)“…GaAsBi alloys are potential candidates for near-infrared optoelectronic applications, such as light-emitting diodes, laser diodes, avalanche photodiodes, and…”
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Raman scattering study on dilute nitride-bismide GaNAsBi alloys: behavior of photo-excited LO phonon-plasmon coupled mode
Published in Japanese Journal of Applied Physics (01-01-2023)“…Abstract We present a Raman scattering study of as-grown and annealed GaAsBi, GaNAs, and GaNAsBi epilayers grown by plasma-assisted molecular beam epitaxy. In…”
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Three-dimensional analysis of pancreatic fat by fat-water magnetic resonance imaging provides detailed characterization of pancreatic steatosis with improved reproducibility
Published in PloS one (02-12-2019)“…Since pancreatic steatosis is reported as a possible risk factor for pancreatic cancer, the development of a non-invasive method to quantify pancreatic…”
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Memantine ameliorates the impairment of social behaviors induced by a single social defeat stress as juveniles
Published in Neuropharmacology (01-10-2022)“…Clinically, juveniles are more sensitive to stress than adults, and exposure to stress as juveniles prolongs psychiatric symptoms and causes treatment…”
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Vagus nerve stimulation even after injury ameliorates cisplatin-induced nephropathy via reducing macrophage infiltration
Published in Scientific reports (11-06-2020)“…The efficacy of prior activation of an anti-inflammatory pathway called the cholinergic anti-inflammatory pathway (CAP) through vagus nerve stimulation (VNS)…”
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Total Synthesis of (±)-4-Deoxyblennolide C via Spirochromanone
Published in Heterocycles (01-01-2021)Get full text
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MRI‐Based Quantitative R2 Mapping at 3 Tesla Reflects Hepatic Iron Overload and Pathogenesis in Nonalcoholic Fatty Liver Disease Patients
Published in Journal of magnetic resonance imaging (01-01-2022)“…Background The role of hepatic iron overload (HIO) in nonalcoholic fatty liver disease (NAFLD) pathogenesis has not been fully elucidated. Purpose This study…”
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The placement of multiple plastic stents still has important roles in candidates for chemotherapy for unresectable perihilar cholangiocarcinoma
Published in Journal of hepato-biliary-pancreatic sciences (01-10-2020)“…Background/Purpose Placement of uncovered self‐expandable metallic stents (U‐SEMSs) of patients with unresectable perihilar cholangiocarcinoma (UPHC) is…”
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Dietary Metabolites and Chronic Kidney Disease
Published in Nutrients (04-04-2017)“…Dietary contents and their metabolites are closely related to chronic kidney disease (CKD) progression. Advanced glycated end products (AGEs) are a type of…”
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Dendritic spine dynamics leading to spine elimination after repeated inductions of LTD
Published in Scientific reports (09-01-2015)“…Memory is fixed solidly by repetition. However, the cellular mechanism underlying this repetition-dependent memory consolidation/reconsolidation remains…”
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