Search Results - "Hasegawa, Kiminori"

B-cell lymphoma developing de novo hepatitis B after salvage therapies including rituximab through seroconversion of surface antibody by Ishihara, Toshimichi, Kanagawa, Michiyo, Koyama, Junichi, Hasegawa, Kiminori, Suzuki, Takashi, Hirayama, Yasuo, Terui, Takeshi

“…The patient was a 73-year-old woman. At 63 years of age, she had developed follicular lymphoma that showed a complete response to R-CHOP therapy. Over the…”
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Hepatocellular carcinoma with multiple lung metastasis resulting in long-term disease-free survival by transcatheter arterial infusion chemotherapy of SMANCS by Koyama, Junichi, Honjo, Shingo, Morizono, Ryutaro, Goto, Tetsu, Morita, Kotaro, Daita, Mitsuru, Hasegawa, Kiminori, Uchizawa, Masahide, Mizuo, Hitoshi

“…The patient was a 61-year-old female with alcoholic liver cirrhosis, who was admitted to our hospital due to elevation of AFP.During the evaluation, both…”
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PTPN22 Deficiency Cooperates with the CD45 E613R Allele to Break Tolerance on a Non-Autoimmune Background by Zikherman, Julie, Hermiston, Michelle, Steiner, David, Hasegawa, Kiminori, Chan, Andrew, Weiss, Arthur

“…Pep and CD45 are tyrosine phosphatases whose targets include the Src-family kinases, critical mediators of Ag receptor signaling. A polymorphism in PTPN22, the…”
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Selective Regulation of Lyn Tyrosine Kinase by CD45 in Immature B Cells by Katagiri, T, Ogimoto, M, Hasegawa, K, Mizuno, K, Yakura, H

“…It has been well established that protein-tyrosine phosphatase CD45 is critically involved in the regulation of initial tyrosine phosphorylation and effector…”
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The Autoimmunity-Associated Gene PTPN22 Potentiates Toll-like Receptor-Driven, Type 1 Interferon-Dependent Immunity by Wang, Yaya, Shaked, Iftach, Stanford, Stephanie M., Zhou, Wenbo, Curtsinger, Julie M., Mikulski, Zbigniew, Shaheen, Zachary R., Cheng, Genhong, Sawatzke, Kristy, Campbell, Amanda M., Auger, Jennifer L., Bilgic, Hatice, Shoyama, Fernanda M., Schmeling, David O., Balfour, Henry H., Hasegawa, Kiminori, Chan, Andrew C., Corbett, John A., Binstadt, Bryce A., Mescher, Matthew F., Ley, Klaus, Bottini, Nunzio, Peterson, Erik J.

“…Immune cells sense microbial products through Toll-like receptors (TLR), which trigger host defense responses including type 1 interferons (IFNs) secretion. A…”
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Cartilage quantification using contrast-enhanced MRI in the wrist of rheumatoid arthritis: cartilage loss is associated with bone marrow edema by Fujimori, Motoshi, Nakamura, Satoko, Hasegawa, Kiminori, Ikeno, Kunihiro, Ichikawa, Shota, Sutherland, Kenneth, Kamishima, Tamotsu

“…To quantify wrist cartilage using contrast MRI and compare with the extent of adjacent synovitis and bone marrow edema (BME) in patients with rheumatoid…”
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PEST Domain-Enriched Tyrosine Phosphatase (PEP) Regulation of Effector/Memory T Cells by Hasegawa, Kiminori, Martin, Flavius, Huang, Guangming, Tumas, Dan, Diehl, Lauri, Chan, Andrew C.

“…Protein tyrosine kinases and phosphatases cooperate to regulate normal immune cell function. We examined the role of PEST domain-enriched tyrosine phosphatase…”
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PTPN22 deficiency cooperates with the CD45 E613R wedge allele to break tolerance on a non-autoimmune background (49.18) by Zikherman, Julie, Hermiston, Michelle, Steiner, David, Hasegawa, Kiminori, Chan, Andrew

“…Abstract Pep and CD45 are tyrosine phosphatases whose targets include the Src-family kinases, critical mediators of antigen receptor signaling. A polymorphism…”
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Induction of CD45 isoform switch in murine B cells by antigen receptor stimulation and by phorbol myristate acetate and ionomycin by Ogimoto, M, Katagiri, T, Hasegawa, K, Mizuno, K, Yakura, H

“…In this study, we examined whether CD45 isoform can be switched in murine mature B cells and what signals are responsible for the process. Stimulation of…”
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The Autoimmunity-Associated GenePTPN22Potentiates Toll-like Receptor-Driven, Type 1 Interferon-Dependent Immunity by Wang, Yaya, Shaked, Iftach, Stanford, Stephanie M, Zhou, Wenbo, Curtsinger, Julie M, Mikulski, Zbigniew, Shaheen, Zachary R, Cheng, Genhong, Sawatzke, Kristy, Campbell, Amanda M, Auger, Jennifer L, Bilgic, Hatice, Shoyama, Fernanda M, Schmeling, David O, Balfour, Henry H, Hasegawa, Kiminori, Chan, Andrew C, Corbett, John A, Binstadt, Bryce A, Mescher, Matthew F, Ley, Klaus, Bottini, Nunzio, Peterson, Erik J

“…Immune cells sense microbial products through Toll-like receptors (TLR), which trigger host defense responses including type 1 interferons (IFNs) secretion. A…”
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Overexpression of the oncoprotein prothymosin α triggers a p53 response that involves p53 acetylation by KOBAYASHI, Takahiko, TING WANG, TANAKA, Junji, IMAMURA, Masahiro, HASEGAWA, Kiminori, TANAKA, Yoshiyuki, BRACHMANN, Rainer K, MAEZAWA, Masaji, KOBAYASHI, Masanobu, OHNISHI, Shunsuke, HATANAKA, Kazuteru, HIGE, Shuhei, SHIMIZU, Yuichi, KATO, Mototsugu, ASAKA, Masahiro

“…Activation of the tumor suppressor protein p53 is a critical cellular response to various stress stimuli and to inappropriate activity of growth-promoting…”
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CD45 Negatively Regulates Lyn Activity by Dephosphorylating Both Positive and Negative Regulatory Tyrosine Residues in Immature B Cells by Katagiri, Tatsuo, Ogimoto, Mami, Hasegawa, Kiminori, Arimura, Yutaka, Mitomo, Katsuyuki, Okada, Masato, Clark, Marcus R, Mizuno, Kazuya, Yakura, Hidetaka

“…Using CD45-deficient clones from the immature B cell line, WEHI-231, we previously demonstrated that CD45 selectively dephosphorylates the Src-family protein…”
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A review for recent advances in AA amyloid research and therapeutic approach to AA amyloidosis complicating rheumatoid arthritis by Tamura, Hiroaki, Hasegawa, Kiminori

“…AA amyloidosis is a life threatening clinical complication of chronic inflammatory diseases such as rheumatoid arthritis. It has been demonstrated…”
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Hematopoietic cell phosphatase, SHP-1, is constitutively associated with the SH2 domain-containing leukocyte protein, SLP-76, in B cells by Mizuno, K, Katagiri, T, Hasegawa, K, Ogimoto, M, Yakura, H

“…Src homology region 2 (SH2) domain-containing phosphatase 1 (SHP-1; previously named HCP, PTP1C, SH-PTP1, and SHP) is a cytosolic protein tyrosine phosphatase…”
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MPTP delta, a putative murine homolog of HPTP delta, is expressed in specialized regions of the brain and in the B-cell lineage by MIZUNO, K, HASEGAWA, K, TAKAGIRI, T, OGIMOTO, M, ICHIKAWA, T, YAKURA, H

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Requirement of PEST domain tyrosine phosphatase PEP in B cell antigen receptor‐induced growth arrest and apoptosis by Hasegawa, Kiminori, Yajima, Hiroaki, Katagiri, Tatsuo, Ogimoto, Mami, Arimura, Yutaka, Mitomo, Katsuyuki, Mashima, Keisuke, Mizuno, Kazuya, Yakura, Hidetaka

“…Signaling events leading to B cell growth or apoptosis are beginning to be unravelled, but detailed information is still lacking. To identify signaling…”
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SHP-1 is involved in neuronal differentiation of P19 embryonic carcinoma cells by Mizuno, Kazuya, Katagiri, Tatsuo, Maruyama, Etsuko, Hasegawa, Kiminori, Ogimoto, Mami, Yakura, Hidetaka

“…Accumulating evidence suggests that tyrosine phosphorylation plays an important role in the development of the central nervous system and in the…”
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Developmental regulation of gene expression for the MPTPδ isoforms in the central nervous system and the immune system by Mizuno, Kazuya, Hasegawa, Kiminori, Ogimoto, Mami, Katagiri, Tatsuo, Yakura, Hidetaka

“…MPTPδ is a murine transmembrane protein tyrosine phosphatase which has three isoforms, types A–C, differing in the structure of the extracellular regions. In…”
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Antigen receptor-initiated growth inhibition is blocked in CD45-loss variants of a mature B lymphoma, with limited effects on apoptosis by Ogimoto, M, Katagiri, T, Mashima, K, Hasegawa, K, Mizuno, K, Yakura, H

“…Role of CD45 in B cell antigen receptor (BcR)-mediated signaling events in mature B cells was examined using BAL-17 and its CD45-negative clones. In the…”
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Negative regulation of apoptotic death in immature B cells by CD45 by Ogimoto, M, Katagiri, T, Mashima, K, Hasegawa, K, Mizuno, K, Yakura, H

“…Cross-linking of membrane IgM receptor on B cells induces tyrosine phosphorylation within 1 min. This biochemical alteration triggers a cascade of signaling…”
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