Search Results - "Hasegawa, Asami"
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Design and synthesis of 2α-(tetrazolylethyl)-1α,25-dihydroxyvitamin D3 as a high affinity ligand for vitamin D receptor
Published in The Journal of steroid biochemistry and molecular biology (01-10-2014)“…•We synthesized 2α-heteroarylethyl active vitamin D3 for SAR study.•The 2α-[2-(tetrazol-2-yl)ethyl] group enhanced transactivation activity.•X-ray…”
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Synthesis of 2α-Heteroarylalkyl Active Vitamin D3 with Therapeutic Effect on Enhancing Bone Mineral Density in Vivo
Published in ACS medicinal chemistry letters (11-07-2013)“…2α-Heteroarylethyl-1α,25-dihydroxyvitamin D3 analogues, which were designed to form a hydrogen bond between Arg274 of human vitamin D receptor (hVDR) and a…”
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Synthesis of 2α-Heteroarylalkyl Active Vitamin D 3 with Therapeutic Effect on Enhancing Bone Mineral Density in Vivo
Published in ACS medicinal chemistry letters (11-07-2013)Get full text
Journal Article