Search Results - "Hasanpourghadi, Mohadeseh"

Caffeic Acid Phenethyl Ester Attenuates Dextran Sulfate Sodium-Induced Ulcerative Colitis Through Modulation of NF-κB and Cell Adhesion Molecules by Pandurangan, Ashok Kumar, Mohebali, Nooshin, Hasanpourghadi, Mohadeseh, Esa, Norhaizan Mohd

“…Ulcerative colitis (UC) is a serious health condition and defined as inflammation in the colon. Untreated, UC can develop into colitis-associated cancer (CAC),…”
Get full text

Phytometabolites Targeting the Warburg Effect in Cancer Cells: A Mechanistic Review by Hasanpourghadi, Mohadeseh, Looi, Chung Yeng, Pandurangan, Ashok Kumar, Sethi, Gautam, Wong, Won Fen, Mustafa, Mohd Rais

“…Phytometabolites are functional elements derived from plants and most of them exhibit therapeutic characteristics such as anti-cancer, anti-inflammatory and…”
Get more information

Hepatitis B virus polymerase-specific T cell epitopes shift in a mouse model of chronic infection by Hasanpourghadi, Mohadeseh, Novikov, Mikhail, Newman, Dakota, Xiang, ZhiQuan, Zhou, Xiang Yang, Magowan, Colin, Ertl, Hildegund C J

“…Chronic hepatitis B virus (HBV) infection (CHB) is a significant public health problem that could benefit from treatment with immunomodulators. Here we…”
Get full text

Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo by Ananda Sadagopan, Suresh Kumar, Mohebali, Nooshin, Looi, Chung Yeng, Hasanpourghadi, Mohadeseh, Pandurangan, Ashok Kumar, Arya, Aditya, Karimian, Hamed, Mustafa, Mohd Rais

“…Natural compounds have been demonstrated to lower breast cancer risk and sensitize tumor cells to anticancer therapies. Recently, we demonstrated that…”
Get full text

Preclinical Immunogenicity and Efficacy Studies for Therapeutic Vaccines for Human Papillomavirus-Type-16-Associated Cancer by Mohammadi, Mohsen, Saha, Amara, Giles-Davis, Wynetta, Xiang, Zhiquan, Novikov, Mikhail, Hasanpourghadi, Mohadeseh, C J Ertl, Hildegund

“…The objective of this study was to conduct preclinical immunogenicity and efficacy studies with several therapeutic vaccines for human papillomavirus…”
Get full text

Treatment with the PPARα agonist fenofibrate improves the efficacy of CD8+ T cell therapy for melanoma by Hasanpourghadi, Mohadeseh, Chekaoui, Arezki, Kurian, Sophia, Kurupati, Raj, Ambrose, Robert, Giles-Davis, Wynetta, Saha, Amara, Xiaowei, Xu, Ertl, Hildegund C.J.

“…Adoptive transfer of tumor antigen-specific CD8+ T cells can limit tumor progression but is hampered by the T cells’ rapid functional impairment within the…”
Get full text

The role of miRNAs 34a, 146a, 320a and 542 in the synergistic anticancer effects of methyl 2-(5-fluoro-2-hydroxyphenyl)-1H- benzo[d]imidazole-5-carboxylate (MBIC) with doxorubicin in breast cancer cells by Hasanpourghadi, Mohadeseh, Abdul Majid, Nazia, Rais Mustafa, Mohd

“…Combination Index (CI) analysis suggested that MBIC and doxorubicin synergistically inhibited up to 97% of cell proliferation in ER /PR MCF-7 and triple…”
Get full text

Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell by Hasanpourghadi, Mohadeseh, Karthikeyan, Chandrabose, Pandurangan, Ashok Kumar, Looi, Chung Yeng, Trivedi, Piyush, Kobayashi, Kinue, Tanaka, Kozo, Wong, Won Fen, Mustafa, Mohd Rais

“…Microtubule Targeting Agents (MTAs) including paclitaxel, colchicine and vinca alkaloids are widely used in the treatment of various cancers. As with most…”
Get full text

(6E,10E) Isopolycerasoidol and (6E,10E) Isopolycerasoidol Methyl Ester, Prenylated Benzopyran Derivatives from Pseuduvaria monticola Induce Mitochondrial-Mediated Apoptosis in Human Breast Adenocarcinoma Cells by Taha, Hairin, Looi, Chung Yeng, Arya, Aditya, Wong, Won Fen, Yap, Lee Fah, Hasanpourghadi, Mohadeseh, Mohd, Mustafa A, Paterson, Ian C, Mohd Ali, Hapipah

“…Phytochemicals from Pseuduvaria species have been reported to display a wide range of biological activities. In the present study, a known benzopyran…”
Get full text

Intrahepatic CD8+ T cells correlate with significant declines in HBV viral load and S antigen following a single vaccination with VRON-0200 in an AAV mouse model by Hasanpourghadi, Mohadeseh, Luber, Andrew, Currie, Sue, Zhou, Xiang, Ertl, Hildegund

Get full text

TOP-107 - Intrahepatic CD8+ T cells correlate with significant declines in HBV viral load and S antigen following a single vaccination with VRON-0200 in an AAV mouse model by Hasanpourghadi, Mohadeseh, Luber, Andrew, Currie, Sue, Zhou, Xiang, Ertl, Hildegund

Get full text

Modulation of oncogenic transcription factors by bioactive natural products in breast cancer by Hasanpourghadi, Mohadeseh, Pandurangan, Ashok Kumar, Mustafa, Mohd Rais

“…[Display omitted] Carcinogenesis, a multi-step phenomenon, characterized by alterations at genetic level and affecting the main intracellular pathways…”
Get full text

COVID-19 Vaccines Based on Adenovirus Vectors by Hasanpourghadi, Mohadeseh, Novikov, Mikhail, Ertl, Hildegund C.J.

Get full text

FRI351 - Immunogenicity and efficacy of an HBV vaccine with an intrinsic checkpoint inhibitor by Hasanpourghadi, Mohadeseh, Luber, Andrew, Magowan, Colin, Zhou, Xiang, Ertl, Hildegund

Get full text

Immunogenicity and efficacy of an HBV vaccine with an intrinsic checkpoint inhibitor by Hasanpourghadi, Mohadeseh, Luber, Andrew, Magowan, Colin, Zhou, Xiang, Ertl, Hildegund

Get full text

Activation of autophagy by stress-activated signals as a cellular self-defense mechanism against the cytotoxic effects of MBIC in human breast cancer cells in vitro by Hasanpourghadi, Mohadeseh, Majid, Nazia Abdul, Mustafa, Mohd Rais

“…[Display omitted] We recently reported that methyl 2-(-5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) is a microtubule targeting agent…”
Get full text

Boldine suppresses dextran sulfate sodium-induced mouse experimental colitis: NF-κB and IL-6/STAT3 as potential targets by Pandurangan, Ashok Kumar, Mohebali, Nooshin, Hasanpourghadi, Mohadeseh, Looi, Chung Yeng, Mustafa, Mohd Rais, Mohd Esa, Norhaizan

“…Ulcerative colitis (UC) is a nonspecific inflammatory disorder characterized by oxidative and nitrosative stress, leucocyte infiltration, and upregulation of…”
Get full text

Heterologous chimpanzee adenovirus vector immunizations for SARS-CoV-2 spike and nucleocapsid protect hamsters against COVID-19 by Hasanpourghadi, Mohadeseh, Novikov, Mikhail, Ambrose, Robert, Chekaoui, Arezki, Newman, Dakota, Ding, Jianyi, Giles-Davis, Wynetta, Xiang, Zhiquan, Zhou, Xiang Yang, Liu, Qin, Swagata, Kar, Ertl, Hildegund CJ

“…Available COVID-19 vaccine only provide protection for a limited time due in part to the rapid emergence of viral variants with spike protein mutations,…”
Get full text

Synthesis, characterization and apoptotic activity of quinazolinone Schiff base derivatives toward MCF-7 cells via intrinsic and extrinsic apoptosis pathways by Zahedifard, Maryam, Lafta Faraj, Fadhil, Paydar, Mohammadjavad, Yeng Looi, Chung, Hajrezaei, Maryam, Hasanpourghadi, Mohadeseh, Kamalidehghan, Behnam, Abdul Majid, Nazia, Mohd Ali, Hapipah, Ameen Abdulla, Mahmood

“…The current study investigated the cytotoxic effect of 3-(5-chloro-2-hydroxybenzylideneamino)-2-(5-chloro-2-hydroxyphenyl)-2,3-dihydroquinazolin-41(H)-one (A)…”
Get full text

Mechanisms of the anti-tumor activity of Methyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo[d]imidazole-5-carboxylate against breast cancer in vitro and in vivo by Hasanpourghadi, Mohadeseh, Pandurangan, Ashok Kumar, Karthikeyan, Chandrabose, Trivedi, Piyush, Mustafa, Mohd Rais

“…Microtubule Targeting Agents (MTAs) induce cell death through mitotic arrest, preferentially affecting rapidly dividing cancer cells over slowly proliferating…”
Get full text