Search Results - "Haryadi, Ryan"

Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research by Haryadi, Ryan, Chan, Kah Fai, Lin, Pao Chun, Tan, Yun Lei, Wan, Corrine, Shahreel, Wahyu, Tay, Shi Jie, Nguyen-Khuong, Terry, Walsh, Ian, Song, Zhiwei

“…This report describes the development and characterization of a comprehensive collection of CHO cell glycosylation mutants with significant potential for…”
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Optimization of heavy chain and light chain signal peptides for high level expression of therapeutic antibodies in CHO cells by Haryadi, Ryan, Ho, Steven, Kok, Yee Jiun, Pu, Helen X, Zheng, Lu, Pereira, Natasha A, Li, Bin, Bi, Xuezhi, Goh, Lin-Tang, Yang, Yuansheng, Song, Zhiwei

“…Translocation of a nascent protein from the cytosol into the ER mediated by its signal peptide is a critical step in protein secretion. The aim of this work…”
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The Isolation Characterisation and Application of CHO Glycosylation Mutant Cell Lines in Biotherapeutics by Haryadi, Ryan

“…We aimed to generate CHO glycosylation mutant cell lines through lectin isolation and gene editing techniques, to gain deeper understanding of the…”
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Identification of functional elements of the GDP-fucose transporter SLC35C1 using a novel Chinese hamster ovary mutant by Zhang, Peiqing, Haryadi, Ryan, Chan, Kah Fai, Teo, Gavin, Goh, John, Pereira, Natasha Ann, Feng, Huatao, Song, Zhiwei

“…The GDP-fucose transporter SLC35C1 critically regulates the fucosylation of glycans. Elucidation of its structure-function relationships remains a challenge…”
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CHO-gmt5, a novel CHO glycosylation mutant for producing afucosylated and asialylated recombinant antibodies by Haryadi, Ryan, Zhang, Peiqing, Chan, Kah Fai, Song, Zhiwei

“…Engineered zinc-finger nucleases (ZFNs) are powerful tools for creating double-stranded-breaks (DSBs) in genomic DNA in a site-specific manner. These DSBs…”
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CHO glycosylation mutants as potential host cells to produce therapeutic proteins with enhanced efficacy by Zhang, Peiqing, Chan, Kah Fai, Haryadi, Ryan, Bardor, Muriel, Song, Zhiwei

“…CHO glycosylation mutants, pioneered by Stanley and co-workers, have proven to be valuable tools in glycobiology and biopharmaceutical research. Here we aim to…”
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CHO-gmt5, a novel CHO glycosylation mutant for producing afucosylated and asialylated recombinant antibodies by Ryan Haryadi, Zhiwei Song, Peiqing Zhang, Kah Fai Chan

“…Engineered zinc-finger nucleases (ZFNs) are powerful tools for creating double-stranded-breaks (DSBs) in genomic DNA in a site-specific manner. These DSBs…”
Get full text