Search Results - "Harwood, L"

Polyunsaturated Fatty Acids: Conversion to Lipid Mediators, Roles in Inflammatory Diseases and Dietary Sources by Harwood, John L

“…Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their role was first established when the essential fatty acids (EFAs)…”
Get full text

Oxidation of polyunsaturated fatty acids to produce lipid mediators by Christie, William W, Harwood, John L

“…The chemistry, biochemistry, pharmacology and molecular biology of oxylipins (defined as a family of oxygenated natural products that are formed from…”
Get more information

Algae: Critical Sources of Very Long-Chain Polyunsaturated Fatty Acids by Harwood, John L

“…Polyunsaturated fatty acids (PUFAs), which are divided into n-3 and n-6 classes, are essential for good health in humans and many animals. They are metabolised…”
Get full text

The Prevalence of Parent-Reported Autism Spectrum Disorder Among US Children by Kogan, Michael D, Vladutiu, Catherine J, Schieve, Laura A, Ghandour, Reem M, Blumberg, Stephen J, Zablotsky, Benjamin, Perrin, James M, Shattuck, Paul, Kuhlthau, Karen A, Harwood, Robin L, Lu, Michael C

“…: media-1vid110.1542/5839990273001PEDS-VA_2017-4161 OBJECTIVES: To estimate the national prevalence of parent-reported autism spectrum disorder (ASD) diagnosis…”
Get full text

Acyl-CoA:diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control by Chen, Guanqun, Harwood, John L., Lemieux, M. Joanne, Stone, Scot J., Weselake, Randall J.

“…Acyl-CoA:diacylglycerol acyltransferase (DGAT, EC 2.3.1.20) catalyzes the last reaction in the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT…”
Get full text

A raison d’être for two distinct pathways in the early steps of plant isoprenoid biosynthesis? by Hemmerlin, Andréa, Harwood, John L., Bach, Thomas J.

“…When compared to other organisms, plants are atypical with respect to isoprenoid biosynthesis: they utilize two distinct and separately compartmentalized…”
Get full text

Membrane lipid therapy: Modulation of the cell membrane composition and structure as a molecular base for drug discovery and new disease treatment by Escribá, Pablo V., Busquets, Xavier, Inokuchi, Jin-ichi, Balogh, Gábor, Török, Zsolt, Horváth, Ibolya, Harwood, John L., Vígh, László

“…Nowadays we understand cell membranes not as a simple double lipid layer but as a collection of complex and dynamic protein–lipid structures and microdomains…”
Get full text

Spatial and Temporal Mapping of Key Lipid Species in Brassica napus Seeds by Woodfield, Helen K., Sturtevant, Drew, Borisjuk, Ljudmilla, Munz, Eberhard, Guschina, Irina A., Chapman, Kent, Harwood, John L.

“…The regulation of lipid synthesis in oil seeds is still not fully understood. Oilseed rape (Brassica napus) is the third most productive vegetable oil crop on…”
Get full text

Key role of lipids in heat stress management by Balogh, Gábor, Péter, Mária, Glatz, Attila, Gombos, Imre, Török, Zsolt, Horváth, Ibolya, Harwood, John L., Vígh, László

“…Heat stress is a common and, therefore, an important environmental impact on cells and organisms. While much attention has been paid to severe heat stress,…”
Get full text

Mitochondrial uncoupling prodrug improves tissue sparing, cognitive outcome, and mitochondrial bioenergetics after traumatic brain injury in male mice by Hubbard, W. Brad, Harwood, Christopher L., Geisler, John G., Vekaria, Hemendra J., Sullivan, Patrick G.

“…Traumatic brain injury (TBI) results in cognitive impairment, which can be long‐lasting after moderate to severe TBI. Currently, there are no FDA‐approved…”
Get full text

Light-Induced Changes in Fatty Acid Profiles of Specific Lipid Classes in Several Freshwater Phytoplankton Species by Wacker, Alexander, Piepho, Maike, Harwood, John L, Guschina, Irina A, Arts, Michael T

“…We tested the influence of two light intensities [40 and 300 μmol PAR / (m(2)s)] on the fatty acid composition of three distinct lipid classes in four…”
Get full text

In silico characterization and expression profiling of the diacylglycerol acyltransferase gene family (DGAT1, DGAT2, DGAT3 and WS/DGAT) from oil palm, Elaeis guineensis by Rosli, Rozana, Chan, Pek-Lan, Chan, Kuang-Lim, Amiruddin, Nadzirah, Low, Eng-Ti Leslie, Singh, Rajinder, Harwood, John L, Murphy, Denis J

“…•Genes encoding four distinct functional families of diacylglycerol acyltransferases (DGAT) enzymes were characterised in the genome of the African oil…”
Get full text

Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease by Bascoul-Colombo, Cécile, Guschina, Irina A., Maskrey, Benjamin H., Good, Mark, O'Donnell, Valerie B., Harwood, John L.

“…Alzheimer's disease (AD) is of major concern in ageing populations and we have used the Tg2576 mouse model to understand connections between brain lipids and…”
Get full text

Mechanisms of temperature adaptation in poikilotherms by Guschina, Irina A., Harwood, John L.

“…For good function, membrane lipids have to be arranged appropriately and be in the correct physical state. In poikilotherms, exposure to cold stress or heat…”
Get full text

Lipids and lipid metabolism in eukaryotic algae by Guschina, Irina A., Harwood, John L.

“…Eukaryotic algae are a very diverse group of organisms which inhabit a huge range of ecosystems from the Antarctic to deserts. They account for over half the…”
Get full text

Metal removal from soil leachates using DTPA-functionalised maghemite nanoparticles, a potential soil washing technology by Hughes, D.L., Afsar, A., Laventine, D.M., Shaw, E.J., Harwood, L.M., Hodson, M.E.

“…There is significant current interest in the application of magnetic (magnetite or maghemite) nanoparticles functionalised with chelating agents for the…”
Get full text

Nanogel vaccines targeting dendritic cells: Contributions of the surface decoration and vaccine cargo on cell targeting and activation by Thomann-Harwood, L.J., Kaeuper, P., Rossi, N., Milona, P., Herrmann, B., McCullough, K.C.

“…Dendritic cells (DCs) play crucial roles in initiating and promoting immune defences, providing a pivotal target for vaccines. Although…”
Get full text

Increasing the flow of carbon into seed oil by Weselake, Randall J., Taylor, David C., Rahman, M. Habibur, Shah, Saleh, Laroche, André, McVetty, Peter B.E., Harwood, John L.

“…The demand for vegetable oils for food, fuel (bio-diesel) and bio-product applications is increasing rapidly. In Canada alone, it is estimated that a 50 to 75%…”
Get full text

Genetic Manipulation of Biosynthetic Pathways in Mint by Fuchs, Lorenz K., Holland, Alistair H., Ludlow, Richard A., Coates, Ryan J., Armstrong, Harvey, Pickett, John A., Harwood, John L., Scofield, Simon

“…In recent years, the study of aromatic plants has seen an increase, with great interest from industrial, academic, and pharmaceutical industries. Among plants…”
Get full text

Transgenic manipulation of triacylglycerol biosynthetic enzymes in B. napus alters lipid-associated gene expression and lipid metabolism by Liao, Pan, Lechon, Tamara, Romsdahl, Trevor, Woodfield, Helen, Fenyk, Stepan, Fawcett, Tony, Wallington, Emma, Bates, Ruth E., Chye, Mee-Len, Chapman, Kent D., Harwood, John L., Scofield, Simon

“…Oilseed rape ( Brassica napus ) is an important crop that is cultivated for the oil (mainly triacylglycerol; TAG) it produces in its seeds. TAG synthesis is…”
Get full text