Search Results - "Harvey, Tracey J"
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Investigating cortical features of Sotos syndrome using mice heterozygous for Nsd1
Published in Genes, brain and behavior (01-04-2020)“…Sotos syndrome is a developmental disorder characterized by a suite of clinical features. In children, the three cardinal features of Sotos syndrome are a…”
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Genome-wide transcriptomic analysis of the forebrain of postnatal Slc13a4 +/- mice
Published in BMC research notes (13-07-2021)“…Sulfation is an essential physiological process that regulates the function of a wide array of molecules involved in brain development. We have previously…”
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3
Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus
Published in Scientific reports (16-05-2016)“…Within the adult mammalian brain, neurogenesis persists within two main discrete locations, the subventricular zone lining the lateral ventricles and the…”
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4
Transcriptional regulation of ependymal cell maturation within the postnatal brain
Published in Neural development (16-02-2018)“…Radial glial stem cells within the developing nervous system generate a variety of post-mitotic cells, including neurons and glial cells, as well as the…”
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5
Alterations in gene expression in the spinal cord of mice lacking Nfix
Published in BMC research notes (16-09-2020)“…Nuclear Factor One X (NFIX) is a transcription factor expressed by neural stem cells within the developing mouse brain and spinal cord. In order to…”
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Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development
Published in Cerebellum (London, England) (01-02-2020)“…Transcriptional regulation plays a central role in controlling neural stem and progenitor cell proliferation and differentiation during neurogenesis. For…”
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NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF
Published in EBioMedicine (01-02-2017)“…While invasion and metastasis of tumour cells are the principle factor responsible for cancer related deaths, the mechanisms governing the process remain…”
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Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX
Published in Brain research (07-08-2015)“…Abstract Nuclear factor one X (NFIX) has been shown to play a pivotal role during the development of many regions of the brain, including the neocortex, the…”
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Hydrocephalus in Nfix−/− Mice Is Underpinned by Changes in Ependymal Cell Physiology
Published in Cells (Basel, Switzerland) (02-08-2022)“…Nuclear factor one X (NFIX) is a transcription factor required for normal ependymal development. Constitutive loss of Nfix in mice (Nfix−/−) is associated with…”
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10
Cell-extrinsic requirement for sulfate in regulating hippocampal neurogenesis
Published in Biology open (31-07-2020)“…Sulfate is a key anion required for a range of physiological functions within the brain. These include sulfonation of extracellular proteoglycans to facilitate…”
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11
Tetracycline-Inducible Packaging Cell Line for Production of Flavivirus Replicon Particles
Published in Journal of Virology (01-01-2004)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Systematic analysis of the transcriptional landscape of melanoma reveals drug-target expression plasticity
Published in Briefings in functional genomics (05-01-2024)“…Metastatic melanoma originates from melanocytes of the skin. Melanoma metastasis results in poor treatment prognosis for patients and is associated with…”
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13
Kunjin Virus Replicon Vaccine Vectors Induce Protective CD8+ T-Cell Immunity
Published in Journal of Virology (01-04-2002)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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14
Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression
Published in Development (Cambridge) (01-02-2018)“…Our understanding of the transcriptional programme underpinning adult hippocampal neurogenesis is incomplete. In mice, under basal conditions, adult…”
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Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice
Published in Journal of comparative neurology (1911) (01-08-2017)“…The nuclear factor I (NFI) family of transcription factors plays an important role in the development of the cerebral cortex in humans and mice. Disruption of…”
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Kunjin Virus Replicon Vectors for Human Immunodeficiency Virus Vaccine Development
Published in Journal of Virology (01-07-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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17
NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development
Published in The Journal of neuroscience (19-02-2014)“…Epigenetic mechanisms are essential in regulating neural progenitor cell self-renewal, with the chromatin-modifying protein Enhancer of zeste homolog 2 (EZH2)…”
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18
NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis
Published in Cerebral cortex (New York, N.Y. 1991) (01-01-2014)“…Neural progenitor cells have the ability to give rise to neurons and glia in the embryonic, postnatal and adult brain. During development, the program…”
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Transcriptional regulation of intermediate progenitor cell generation during hippocampal development
Published in Development (Cambridge) (15-12-2016)“…During forebrain development, radial glia generate neurons through the production of intermediate progenitor cells (IPCs). The production of IPCs is a central…”
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Cell-type-specific expression of NFIX in the developing and adult cerebellum
Published in Brain Structure and Function (01-07-2017)“…Transcription factors from the nuclear factor one (NFI) family have been shown to play a central role in regulating neural progenitor cell differentiation…”
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