Search Results - "Harvey, Theresa L"
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Postsynaptic Serine Racemase Regulates NMDA Receptor Function
Published in The Journal of neuroscience (09-12-2020)“…d-serine is the primary NMDAR coagonist at mature forebrain synapses and is synthesized by the enzyme serine racemase (SR). However, our understanding of the…”
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d-serine availability modulates prefrontal cortex inhibitory interneuron development and circuit maturation
Published in Scientific reports (13-06-2023)“…The proper development and function of telencephalic GABAergic interneurons is critical for maintaining the excitation and inhibition (E/I) balance in cortical…”
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The D-serine biosynthetic enzyme serine racemase is expressed by reactive astrocytes in the amygdala of human and a mouse model of Alzheimer’s disease
Published in Neuroscience letters (01-01-2023)“…•Reactive astrocytes express serine racemase in the amygdala of human AD cases.•SR producing reactive astrocytes express C3 in the amygdala of human AD…”
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Forebrain expression of serine racemase during postnatal development
Published in Neurochemistry international (01-05-2021)“…N-methyl-D-aspartate receptors (NMDARs) are important for synaptogenesis, synaptic maturation and refinement during the early postnatal weeks after birth…”
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