Search Results - "Harvey, Ruth"

SARS-CoV-2 S2-targeted vaccination elicits broadly neutralizing antibodies by Ng, Kevin W, Faulkner, Nikhil, Finsterbusch, Katja, Wu, Mary, Harvey, Ruth, Hussain, Saira, Greco, Maria, Liu, Yafei, Kjaer, Svend, Swanton, Charles, Gandhi, Sonia, Beale, Rupert, Gamblin, Steve J, Cherepanov, Peter, McCauley, John, Daniels, Rodney, Howell, Michael, Arase, Hisashi, Wack, Andreas, Bauer, David L V, Kassiotis, George

“…Several variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged during the current coronavirus disease 2019 (COVID-19) pandemic…”
Get more information

SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export by Hall, Ross, Guedán, Anabel, Yap, Melvyn W, Young, George R, Harvey, Ruth, Stoye, Jonathan P, Bishop, Kate N

“…SARS-CoV-2 is a betacoronavirus and the etiological agent of COVID-19, a devastating infectious disease. Due to its far-reaching effect on human health, there…”
Get full text

Differential effects of SARS-CoV-2 variants on central nervous system cells and blood-brain barrier functions by Proust, Alizé, Queval, Christophe J, Harvey, Ruth, Adams, Lorin, Bennett, Michael, Wilkinson, Robert J

“…Although mainly causing a respiratory syndrome, numerous neurological symptoms have been identified following of SARS-CoV-2 infection. However, how the virus…”
Get full text

Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein by Wrobel, Antoni G., Benton, Donald J., Hussain, Saira, Harvey, Ruth, Martin, Stephen R., Roustan, Chloë, Rosenthal, Peter B., Skehel, John J., Gamblin, Steven J.

“…The CR3022 antibody, selected from a group of SARS-CoV monoclonal antibodies for its ability to cross-react with SARS-CoV-2, has been examined for its ability…”
Get full text

Breadth and function of antibody response to acute SARS-CoV-2 infection in humans by Huang, Kuan-Ying A, Tan, Tiong Kit, Chen, Ting-Hua, Huang, Chung-Guei, Harvey, Ruth, Hussain, Saira, Chen, Cheng-Pin, Harding, Adam, Gilbert-Jaramillo, Javier, Liu, Xu, Knight, Michael, Schimanski, Lisa, Shih, Shin-Ru, Lin, Yi-Chun, Cheng, Chien-Yu, Cheng, Shu-Hsing, Huang, Yhu-Chering, Lin, Tzou-Yien, Jan, Jia-Tsrong, Ma, Che, James, William, Daniels, Rodney S, McCauley, John W, Rijal, Pramila, Townsend, Alain R

“…Serological and plasmablast responses and plasmablast-derived IgG monoclonal antibodies (MAbs) have been analysed in three COVID-19 patients with different…”
Get full text

A TLR5 mono-agonist restores inhibited immune responses to Streptococcus pneumoniae during influenza virus infection in human monocytes by Maguire, Paula T, Loughran, Sinéad T, Harvey, Ruth, Johnson, Patricia A

“…Influenza A virus (IAV) predisposes individuals to often more severe secondary bacterial infections with Streptococcus pneumonia (S. pneumoniae). The outcomes…”
Get full text

COVID-19 in non-hospitalised adults caused by either SARS-CoV-2 sub-variants Omicron BA.1, BA.2, BA.4/5 or Delta associates with similar illness duration, symptom severity and viral kinetics, irrespective of vaccination history by Townsley, Hermaleigh, Gahir, Joshua, Russell, Timothy W, Greenwood, David, Carr, Edward J, Dyke, Matala, Adams, Lorin, Miah, Murad, Clayton, Bobbi, Smith, Callie, Miranda, Mauro, Mears, Harriet V, Bailey, Chris, Black, James R M, Fowler, Ashley S, Crawford, Margaret, Wilkinson, Katalin, Hutchinson, Matthew, Harvey, Ruth, O'Reilly, Nicola, Kelly, Gavin, Goldstone, Robert, Beale, Rupert, Papineni, Padmasayee, Corrah, Tumena, Gilson, Richard, Caidan, Simon, Nicod, Jerome, Gamblin, Steve, Kassiotis, George, Libri, Vincenzo, Williams, Bryan, Gandhi, Sonia, Kucharski, Adam J, Swanton, Charles, Bauer, David L V, Wall, Emma C

“…SARS-CoV-2 variant Omicron rapidly evolved over 2022, causing three waves of infection due to sub-variants BA.1, BA.2 and BA.4/5. We sought to characterise…”
Get full text

Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies by Gao, Jin, Couzens, Laura, Burke, David F, Wan, Hongquan, Wilson, Patrick, Memoli, Matthew J, Xu, Xiyan, Harvey, Ruth, Wrammert, Jens, Ahmed, Rafi, Taubenberger, Jeffery K, Smith, Derek J, Fouchier, Ron A M, Eichelberger, Maryna C

“…The effectiveness of influenza vaccines against circulating A(H1N1)pdm09 viruses was modest for several seasons despite the absence of antigenic drift of…”
Get full text

Combined analyses of within-host SARS-CoV-2 viral kinetics and information on past exposures to the virus in a human cohort identifies intrinsic differences of Omicron and Delta variants by Russell, Timothy W, Townsley, Hermaleigh, Abbott, Sam, Hellewell, Joel, Carr, Edward J, Chapman, Lloyd A C, Pung, Rachael, Quilty, Billy J, Hodgson, David, Fowler, Ashley S, Adams, Lorin, Bailey, Chris, Mears, Harriet V, Harvey, Ruth, Clayton, Bobbi, O'Reilly, Nicola, Ngai, Yenting, Nicod, Jerome, Gamblin, Steve, Williams, Bryan, Gandhi, Sonia, Swanton, Charles, Beale, Rupert, Bauer, David L V, Wall, Emma C, Kucharski, Adam J

“…The emergence of successive Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) during 2020 to 2022, each exhibiting…”
Get full text

Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains by Faulkner, Nikhil, Ng, Kevin W, Wu, Mary Y, Harvey, Ruth, Margaritis, Marios, Paraskevopoulou, Stavroula, Houlihan, Catherine, Hussain, Saira, Greco, Maria, Bolland, William, Warchal, Scott, Heaney, Judith, Rickman, Hannah, Spyer, Moria, Frampton, Daniel, Byott, Matthew, de Oliveira, Tulio, Sigal, Alex, Kjaer, Svend, Swanton, Charles, Gandhi, Sonia, Beale, Rupert, Gamblin, Steve J, McCauley, John W, Daniels, Rodney Stuart, Howell, Michael, Bauer, David, Nastouli, Eleni, Kassiotis, George

“…Background: The degree of heterotypic immunity induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains is a major determinant of the…”
Get full text

Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus by Harvey, Ruth, Mattiuzzo, Giada, Hassall, Mark, Sieberg, Andrea, Müller, Marcel A, Drosten, Christian, Rigsby, Peter, Oxenford, Christopher J

“…Middle East respiratory syndrome coronavirus (MERS-CoV) was detected in humans in 2012. Since then, sporadic outbreaks with primary transmission through…”
Get full text

Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States by Perofsky, Amanda C, Huddleston, John, Hansen, Chelsea L, Barnes, John R, Rowe, Thomas, Xu, Xiyan, Kondor, Rebecca, Wentworth, David E, Lewis, Nicola, Whittaker, Lynne, Ermetal, Burcu, Harvey, Ruth, Galiano, Monica, Daniels, Rodney Stuart, McCauley, John W, Fujisaki, Seiichiro, Nakamura, Kazuya, Kishida, Noriko, Watanabe, Shinji, Hasegawa, Hideki, Sullivan, Sheena G, Barr, Ian G, Subbarao, Kanta, Krammer, Florian, Bedford, Trevor, Viboud, Cécile

“…Influenza viruses continually evolve new antigenic variants, through mutations in epitopes of their major surface proteins, hemagglutinin (HA) and…”
Get full text

Influenza infection directly alters innate IL-23 and IL-12p70 and subsequent IL-17A and IFN-γ responses to pneumococcus in vitro in human monocytes by Loughran, Sinead T, Power, Patrick A, Maguire, Paula T, McQuaid, Samantha L, Buchanan, Paul J, Jonsdottir, Ingileif, Newman, Robert W, Harvey, Ruth, Johnson, Patricia A

“…Influenza virus is highly contagious and poses substantial public health problems due to its strong association with morbidity and mortality. Approximately…”
Get full text

Electron cryotomography of SARS-CoV-2 virions reveals cylinder-shaped particles with a double layer RNP assembly by Calder, Lesley J., Calcraft, Thomas, Hussain, Saira, Harvey, Ruth, Rosenthal, Peter B.

“…SARS-CoV-2 is a lipid-enveloped Betacoronavirus and cause of the Covid-19 pandemic. To study the three-dimensional architecture of the virus, we perform…”
Get full text

Correction: Breadth and function of antibody response to acute SARS-CoV-2 infection in humans by Huang, Kuan-Ying A, Tan, Tiong Kit, Chen, Ting-Hua, Huang, Chung-Guei, Harvey, Ruth, Hussain, Saira, Chen, Cheng-Pin, Harding, Adam, Gilbert-Jaramillo, Javier, Liu, Xu, Knight, Michael, Schimanski, Lisa, Shih, Shin-Ru, Lin, Yi-Chun, Cheng, Chien-Yu, Cheng, Shu-Hsing, Huang, Yhu-Chering, Lin, Tzou-Yien, Jan, Jia-Tsrong, Ma, Che, James, William, Daniels, Rodney S, McCauley, John W, Rijal, Pramila, Townsend, Alain R

“…[This corrects the article DOI: 10.1371/journal.ppat.1009352.]…”
Get full text

The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain by Wan, Hongquan, Gao, Jin, Yang, Hua, Yang, Shuang, Harvey, Ruth, Chen, Yao-Qing, Zheng, Nai-Ying, Chang, Jessie, Carney, Paul J., Li, Xing, Plant, Ewan, Jiang, Lianlian, Couzens, Laura, Wang, Carol, Strohmeier, Shirin, Wu, Wells W., Shen, Rong-Fong, Krammer, Florian, Cipollo, John F., Wilson, Patrick C., Stevens, James, Wan, Xiu-Feng, Eichelberger, Maryna C., Ye, Zhiping

“…A(H3N2) virus predominated recent influenza seasons, which has resulted in the rigorous investigation of haemagglutinin, but whether neuraminidase (NA) has…”
Get full text

The Ability of a Non-Egg Adapted (Cell-Like) A(H1N1)pdm09 Virus to Egg-Adapt at HA Loci Other than 222 and 223 and Its Effect on the Yield of Viral Protein by Nicolson, Carolyn, Harvey, Ruth, Engelhardt, Othmar G, Robertson, James S

“…Previous studies on influenza A(H1N1)pdm09 candidate vaccine viruses (CVVs) that had adapted to growth in embryonated chicken eggs by the acquisition of amino…”
Get full text

Development of Lentivirus-Based Reference Materials for Ebola Virus Nucleic Acid Amplification Technology-Based Assays by Mattiuzzo, Giada, Ashall, James, Doris, Kathryn S, MacLellan-Gibson, Kirsty, Nicolson, Carolyn, Wilkinson, Dianna E, Harvey, Ruth, Almond, Neil, Anderson, Robert, Efstathiou, Stacey, Minor, Philip D, Page, Mark

“…The 2013-present Ebola virus outbreak in Western Africa has prompted the production of many diagnostic assays, mostly based on nucleic acid amplification…”
Get full text

Development of an ELISA-Based Potency Assay for Inactivated Influenza Vaccines Using Cross-Reactive Nanobodies by Cheung, Chung Y., Dubey, Sitara, Hadrovic, Martina, Ball, Christina R., Ramage, Walter, McDonald, Jacqueline U., Harvey, Ruth, Hufton, Simon E., Engelhardt, Othmar G.

“…Inactivated vaccines are the main influenza vaccines used today; these are usually presented as split (detergent-disrupted) or subunit vaccines, while…”
Get full text

Improved Antigen Yield in Pandemic H1N1 (2009) Candidate Vaccine Viruses with Chimeric Hemagglutinin Molecules by HARVEY, Ruth, GUILFOYLE, Kate A, ROSEBY, Sarah, ROBERTSON, James S, ENGELHARDT, Othmar G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text