Search Results - "Harvey, Isabelle"
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Inhibition of translation by RNA–small molecule interactions
Published in RNA (Cambridge) (01-04-2002)“…Small molecule ligand–RNA interactions have the potential to influence gene expression at a variety of steps and in a number of ways. Here, we demonstrate that…”
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Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles
Published in RNA (Cambridge) (01-03-2004)“…The National Cancer Institute (NCI) Human Tumor Cell Line Anti-Cancer Drug Screen has evaluated the cytotoxicity profiles of a large number of synthetic…”
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High level of apoptosis and low AKT activation in mass screening as opposed to standard neuroblastoma
Published in Histopathology (01-04-2010)“…Sartelet H, Ohta S, Barrette S, Rougemont A‐Laure, Brevet M, Regairaz M, Harvey I, Bernard C, Fabre M, Gaboury L, Oligny L L, Bosq J, Valteau‐Couanet D &…”
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Forced Engagement of a RNA/Protein Complex by a Chemical Inducer of Dimerization to Modulate Gene Expression
Published in Proceedings of the National Academy of Sciences - PNAS (19-02-2002)“…A general strategy is described for forcing the engagement of an RNA/protein complex by using small-molecule ligands. A bivalent molecule was created by…”
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Role of Immunohistochemical Overexpression of Matrix Metalloproteinases MMP-2 and MMP-11 in the Prognosis of Death by Ovarian Cancer
Published in American journal of clinical pathology (01-02-2008)“…Matrix metalloproteinases (MMPs) are enzymes thought to be involved in tumor invasion. We hypothesized that MMP-2 and MMP-11 overexpression was associated with…”
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Case - Bilateral and recurrent pediatric cystic nephroma associated with DICER1 mutation
Published in Canadian Urological Association journal (01-05-2021)Get full text
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In vitro and in vivo study of human amniotic fluid-derived stem cell differentiation into myogenic lineage
Published in Clinical and experimental medicine (01-03-2010)“…Recent findings have shown that amniotic fluid (AF) could be a putative new source of multipotent stem cells (SC). We investigated whether these human SC could…”
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High-throughput assays probing protein–RNA interactions of eukaryotic translation initiation factors
Published in Analytical biochemistry (2009)“…Protein–RNA interactions are involved in all facets of RNA biology. The identification of small molecules that selectively block such bimolecular interactions…”
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Structure–activity relationships of quassinoids for eukaryotic protein synthesis
Published in Cancer letters (18-03-2005)“…The effect of 63 quassinoids on eukaryotic protein synthesis has been investigated. Seventeen of the tested compounds showed potent in vitro activity, with IC…”
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An upstream open reading frame impedes translation of the huntingtin gene
Published in Nucleic acids research (01-12-2002)“…Expansion of a CAG tract within the huntingtin gene, leading to the production of a protein with an expanded polyglutamine tract, is responsible for…”
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Full-length cDNAs: more than just reaching the ends
Published in Physiological genomics (17-07-2001)“…1 Department of Biochemistry 2 McGill Cancer Center, McGill University, Montreal, Quebec, Canada H3G 1Y6 The development of functional genomic resources is…”
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Inhibitory properties of nucleic acid-binding ligands on protein synthesis
Published in FEBS letters (03-01-2005)“…The use of small molecule inhibitors in the study of cellular processes is a powerful approach to understanding gene function. During the course of a high…”
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Amyloidosis of the seminal vesicles: a local condition with no systemic impact
Published in Annales de pathologie (01-06-2004)“…Localised seminal vesicle amyloidosis is relatively infrequent and we present 9 additional cases. and methods: Those 9 cases were retrospectively retrieved…”
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An Association of Pleuropulmonary Blastoma and Cystic Nephroma: Possible Genetic Association
Published in Pediatric and developmental pathology (01-01-2006)“…The association of pleuropulmonary blastoma and cystic nephroma is an uncommon entity, with only 4 cases of such an association in the same patient described…”
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Inhibition of protein synthesis by aminoglycoside–arginine conjugates
Published in RNA (Cambridge) (01-10-2002)“…Inhibition of translation by small molecule ligands has proven to be a useful tool for understanding this complex cellular mechanism, as well as providing…”
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Bilateral Cystic Dysplasia of the Rete Testis with Renal Adysplasia
Published in Pediatric and developmental pathology (01-03-2006)“…Cystic dyplasia of the rete testis (CDRT) is an uncommon, generally unilateral lesion characterized by anastomosing cystic spaces lined by a flattened simple…”
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Random Amplified Ribosomal DNA Restriction Analysis for Rapid Identification of Thermophilic Actinomycete-like Bacteria Involved in Hypersensitivity Pneumonitis
Published in Systematic and applied microbiology (01-07-2001)“…Hypersensitivity pneumonitis (HP) is a pulmonary disease characterised by inflammation that can be caused by, amongst other substances, a subset of 4…”
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