Search Results - "Harvey, Barrett R."
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Contribution of individual Ebp Pilus subunits of Enterococcus faecalis OG1RF to pilus biogenesis, biofilm formation and urinary tract infection
Published in PloS one (11-07-2013)“…The endocarditis and biofilm-associated pilus (Ebp) operon is a component of the core genome of Enterococcus faecalis that has been shown to be important for…”
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Processing of the major autolysin of E. faecalis, AtlA, by the zinc-metalloprotease, GelE, impacts AtlA septal localization and cell separation
Published in PloS one (19-10-2017)“…AtlA is the major peptidoglycan hydrolase of Enterococcus faecalis involved in cell division and cellular autolysis. The secreted zinc metalloprotease,…”
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3
Functional studies of E. faecalis RNase J2 and its role in virulence and fitness
Published in PloS one (06-04-2017)“…Post-transcriptional control provides bacterial pathogens a method by which they can rapidly adapt to environmental change. Dual exo- and endonucleolytic…”
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4
Lymphatic delivery of etanercept via nanotopography improves response to collagen-induced arthritis
Published in Arthritis research & therapy (31-05-2017)“…Evidence suggests lymphatic function mediates local rheumatoid arthritis (RA) flares. Yet biologics that target the immune system are dosed systemically via…”
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5
Enterococcus faecalis rnjB Is Required for Pilin Gene Expression and Biofilm Formation
Published in Journal of Bacteriology (01-10-2010)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Library Screen Identifies Enterococcus faecalis CcpA, the Catabolite Control Protein A, as an Effector of Ace, a Collagen Adhesion Protein Linked to Virulence
Published in Journal of Bacteriology (01-10-2013)“…The Enterococcus faecalis cell wall-anchored protein Ace is an important virulence factor involved in cell adhesion and infection. Expression of Ace on the…”
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Anchored Periplasmic Expression, a Versatile Technology for the Isolation of High-Affinity Antibodies from Escherichia coli-Expressed Libraries
Published in Proceedings of the National Academy of Sciences - PNAS (22-06-2004)“…Anchored periplasmic expression (APEx) is a technology for the isolation of ligand-binding proteins from combinatorial libraries anchored on the periplasmic…”
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The Enterococcus faecalis EbpA Pilus Protein: Attenuation of Expression, Biofilm Formation, and Adherence to Fibrinogen Start with the Rare Initiation Codon ATT
Published in mBio (26-05-2015)“…The endocarditis and biofilm-associated pili (Ebp) are important in Enterococcus faecalis pathogenesis, and the pilus tip, EbpA, has been shown to play a major…”
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IgG2m4, an engineered antibody isotype with reduced Fc function
Published in mAbs (01-11-2009)“…The Fc region of an antibody mediates effector functions such as antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity…”
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Human Antibody against Shiga Toxin 2 Administered to Piglets after the Onset of Diarrhea Due to Escherichia coli O157:H7 Prevents Fatal Systemic Complications
Published in Infection and Immunity (01-08-2005)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The Fsr Quorum-Sensing System of Enterococcus faecalisModulates Surface Display of the Collagen-Binding MSCRAMM Ace through Regulation of gelE
Published in Journal of Bacteriology (01-09-2011)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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12
Comparison of DOTA and NODAGA as chelators for (64)Cu-labeled immunoconjugates
Published in Nuclear medicine and biology (01-02-2015)“…Bifunctional chelators have been shown to impact the biodistribution of monoclonal antibody (mAb)-based imaging agents. Recently, radiolabeled…”
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13
Engineering of recombinant antibody fragments to methamphetamine by anchored periplasmic expression
Published in Journal of immunological methods (20-01-2006)“…The detection of methamphetamine and other chemically related illicit drugs relies extensively on immunoassays. Here we report the cloning and affinity…”
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14
Anti-Ace monoclonal antibody reduces Enterococcus faecalis aortic valve infection in a rat infective endocarditis model
Published in Pathogens and disease (01-11-2018)“…Abstract Ace (Adhesin to collagen from Enterococcus faecalis) is a cell-wall anchored protein that is expressed conditionally and is important for virulence in…”
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The Fsr Quorum-Sensing System of Enterococcus faecalis Modulates Surface Display of the Collagen-Binding MSCRAMM Ace through Regulation of gelE
Published in Journal of bacteriology (01-09-2011)“…Ace, a known virulence factor and the first identified microbial surface component recognizing adhesive matrix molecule (MSCRAMM) of Enterococcus faecalisis…”
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Targeting pili in enterococcal pathogenesis
Published in Infection and immunity (01-04-2014)“…Passive protection, the administration of antibodies to prevent infection, has garnered significant interest in recent years as a potential prophylactic…”
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Comparison of mAbs targeting epithelial cell adhesion molecule for the detection of prostate cancer lymph node metastases with multimodal contrast agents: quantitative small-animal PET/CT and NIRF
Published in Journal of Nuclear Medicine (01-09-2012)“…The proliferation of most carcinomas is associated with an overexpression of epithelial cell adhesion molecule (EpCAM), a 40-kDa type I transmembrane protein…”
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18
Multimodal Chelation Platform for Near-Infrared Fluorescence/Nuclear Imaging
Published in Journal of medicinal chemistry (24-01-2013)“…Dual-labeled compounds containing nuclear and near-infrared fluorescence contrast have the potential to molecularly guide surgical resection of cancer by…”
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Antibody Guided Molecular Imaging of Infective Endocarditis
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…In this protocol, we describe the application of using a high affinity monoclonal antibody generated against the major pilin protein component of the pilin…”
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Development of a genomic site for gene integration and expression in Enterococcus faecalis
Published in Journal of microbiological methods (01-07-2012)“…Enterococcus faecalis, a gram-positive opportunistic pathogen, has become one of the leading causes of nosocomial infections. Normally a resident of the…”
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