Search Results - "Harvanová, Denisa"
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New therapeutic approaches of mesenchymal stem cells-derived exosomes
Published in Journal of biomedical science (25-05-2021)“…Mesenchymal stem cells (MSCs) have been demonstrated to have a great potential in the treatment of several diseases due to their differentiation and…”
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Treatment of knee joint osteoarthritis with autologous platelet-rich plasma in comparison with hyaluronic acid
Published in American journal of physical medicine & rehabilitation (01-05-2012)“…This study aimed to find a simple, cost-effective, and time-efficient method for the preparation of platelet-rich plasma (PRP), so the acquired benefits will…”
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The Role of Mesenchymal Stromal Cells and Their Products in the Treatment of Injured Spinal Cords
Published in Current issues in molecular biology (01-06-2023)“…Spinal cord injury (SCI) is a destructive condition that results in lasting neurological damage resulting in disruption of the connection between the central…”
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Plasma-derived extracellular vesicle surface markers CD45, CD326 and CD56 correlate with the stage of osteoarthritis: a primary study of a novel and promising diagnostic tool of the disease
Published in Scientific reports (16-11-2023)“…Recently, there is a growing interest in the research based on extracellular vesicles (EVs) which represent paracrine factors secreted by almost all cell…”
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Influence of Kartogenin on Chondrogenic Differentiation of Human Bone Marrow-Derived MSCs in 2D Culture and in Co-Cultivation with OA Osteochondral Explant
Published in Molecules (Basel, Switzerland) (16-01-2018)“…Articular cartilage has limited capacity for natural regeneration and repair. In the present study, we evaluated kartogenin (KGN), a bioactive small…”
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The Role of Synovial Membrane in the Development of a Potential In Vitro Model of Osteoarthritis
Published in International journal of molecular sciences (24-02-2022)“…There is a lack of in vitro models able to plausibly represent the inflammation microenvironment of knee osteoarthritis (OA). We analyzed the molecules…”
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Small Extracellular Vesicles Derived from Human Chorionic MSCs as Modern Perspective towards Cell-Free Therapy
Published in International journal of molecular sciences (18-12-2021)“…Mesenchymal stem cells (MSCs) are of great interest to scientists due to their application in cell therapy of many diseases, as well as regenerative medicine…”
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Mesenchymal Stem Cells in the Treatment of Human Spinal Cord Injury: The Effect on Individual Values of pNF-H, GFAP, S100 Proteins and Selected Growth Factors, Cytokines and Chemokines
Published in Current issues in molecular biology (24-01-2022)“…At present, there is no effective way to treat the consequences of spinal cord injury (SCI). SCI leads to the death of neural and glial cells and widespread…”
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Effect of Intra-Articular Injection of Platelet-Rich Plasma on the Serum Levels of Osteoarthritic Biomarkers in Patients with Unilateral Knee Osteoarthritis
Published in Journal of clinical medicine (11-12-2021)“…The aim of this study is to determine the effect of three doses of intra-articular injection of platelet-rich plasma (PRP) into the osteoarthritic (OA) knee…”
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Transcriptomic Analysis of Macrophage Polarization Protocols: Vitamin D3 or IL-4 and IL-13 Do Not Polarize THP-1 Monocytes into Reliable M2 Macrophages
Published in Biomedicines (17-02-2023)“…Two main types of macrophages (Mφ) include inflammatory (M1) and anti-inflammatory (M2) macrophages. These cells can be obtained in vitro by polarization of…”
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Effect of PRP and PPP on proliferation and migration of human chondrocytes and synoviocytes in vitro
Published in Open life sciences (01-02-2014)Get full text
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New nanostructured nickel–polymer nanohybrids with improved surface hydrophobicity and effect on the living cells adhesion
Published in Applied surface science (15-11-2015)“…•Unique nanohybrid formed from nanostructured nickel covered with polymer layer in being introduced.•Polymer is spin-coated on nanostructured nickel…”
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3D printed Polylactid Acid based porous scaffold for bone tissue engineering: an in vitro study
Published in Acta of bioengineering and biomechanics (2019)“…The objective of this study was to fabricate PLA-based porous scaffold by 3D printing technology and to evaluate their cytotoxicity and biocompatibility under…”
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Novel trisubstituted acridines as human telomeric quadruplex binding ligands
Published in Bioorganic chemistry (01-12-2014)“…[Display omitted] •We studied series of new trisubstituted acridines with calf thymus DNA.•All of the derivatives exhibited stabilizing effects on the human…”
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Impact of different pancreatic microenvironments on improvement in hyperglycemia and insulin deficiency in diabetic rats after transplantation of allogeneic mesenchymal stromal cells
Published in The Journal of surgical research (01-11-2012)“…Abstract Background Mesenchymal stromal cells (MSCs) in the pancreatic microenvironment can improve diabetes mellitus (DM). The aim of the present study was to…”
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Isolation, cultivation and characterisation of pigeon osteoblasts seeded on xenogeneic demineralised cancellous bone scaffold for bone grafting
Published in Veterinary research communications (01-09-2014)“…Avian osteoblasts have been isolated particularly from chicken embryo, but data about other functional tissue sources of adult avian osteoblast precursors are…”
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Reparation of chondral defects in rabbits by autologous and allogenous chondrocytes seeded on collagen/hyaluronan scaffold or suspended in fibrin glue
Published in Acta veterinaria (Beograd) (01-03-2014)“…The topic of the study was to verify in vivo survival of in vitro cultured autologous and allogenous chondrocytes suspended in a fibrin glue Beriplast® or…”
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Isolation and characterization of synovial mesenchymal stem cells
Published in Folia biologica (01-01-2011)“…Synovial membrane and synovial fluid represent a good source of mesenchymal stem cells. They have been regarded as a promising therapeutic tool for…”
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Collagen/hyaluronan membrane as a scaffold for chondrocytes cultivation
Published in Biológia (01-10-2009)“…Rabbit chondrocytes were cultivated in vitro using the collagen/hyaluronan membrane. The membrane did not show any adverse effects on chondrocyte viability…”
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