Search Results - "Haruna, Yoshisuke"
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Renin-angiotensin system inhibitors in hypertensive adults with non-diabetic CKD with or without proteinuria: a systematic review and meta-analysis of randomized trials
Published in Hypertension research (01-04-2019)“…The efficacy and safety of renin-angiotensin system inhibitors (RAS-I) in hypertensive adults with non-diabetic chronic kidney disease (CKD) differ depending…”
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Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice
Published in Clinical and experimental nephrology (01-10-2016)“…Background Expression of klotho, the renoprotective anti-aging gene, is decreased in diabetic model kidneys. We hypothesized that klotho protein attenuates…”
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Amelioration of progressive renal injury by genetic manipulation of Klotho gene
Published in Proceedings of the National Academy of Sciences - PNAS (13-02-2007)“…Klotho, an antiaging gene with restricted organ distribution, is mainly expressed in the kidney tubules; the mutant mice have shortened life span,…”
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Comparison of Left Ventricular Diastolic Function Parameters between Patients with Unplanned and Planned Hemodialysis Initiation: A Cross-Sectional Study
Published in Kidney and dialysis (01-06-2023)“…Despite the increasing number of dialysis patients, there is still no clear consensus regarding when a permanent access device should be prepared and renal…”
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Pioglitazone Enhances the Antihypertensive and Renoprotective Effects of Candesartan in Zucker Obese Rats Fed a High-Protein Diet
Published in Hypertension research (01-04-2008)“…The metabolic syndrome is a risk factor for the development of chronic kidney disease. Angiotensin II type 1 receptor blockers (ARBs) and thiazolidinediones…”
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Establishment of a Blood Purification System for Renal Failure Rats Using Small-Size Dialyzer Membranes
Published in Therapeutic apheresis and dialysis (01-12-2012)“…Hemodialysis techniques for small animals have not been established because no small dialysis apparatus has been available. We recently developed a small‐size…”
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Cardioprotective role of endogenous hydrogen peroxide during ischemia-reperfusion injury in canine coronary microcirculation in vivo
Published in American journal of physiology. Heart and circulatory physiology (01-09-2006)“…We have recently demonstrated that endogenous H2O2 plays an important role in coronary autoregulation in vivo. However, the role of H2O2 during coronary…”
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Prevalence of gastroesophageal reflux disease symptoms and effects of esomeprazole on the quality of life related to reflux and dyspepsia in patients on maintenance hemodialysis
Published in Clinical and experimental nephrology (01-02-2016)“…Background The prevalence of gastroesophageal reflux disease (GERD) symptoms has not been investigated in patients on maintenance hemodialysis in Japan, and…”
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Telmisartan improves endothelial dysfunction and renal autoregulation in Dahl salt-sensitive rats
Published in Hypertension research (01-02-2010)Get full text
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Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy
Published in Clinical and experimental nephrology (01-04-2008)“…Background Serotonin (5-HT) is involved in vascular inflammation and atherosclerogenesis. Serum 5-HT concentrations are elevated in diabetes, and 5-HT is…”
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Isohumulones derived from hops ameliorate renal injury via an anti-oxidative effect in Dahl salt-sensitive rats
Published in Hypertension research (01-02-2007)“…Previous studies have reported that isohumulones, the bitter compounds in beer, improve insulin resistance and hyperlipidemia in several animal models. In this…”
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Olmesartan Ameliorates Progressive Glomerular Injury in Subtotal Nephrectomized Rats through Suppression of Superoxide Production
Published in Hypertension research (01-02-2008)Get full text
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Aging and tubulo-interstitial injuries (possible implications of Klotho): renal senescence hypothesis
Published in Nihon Jinzo Gakkai shi (2012)Get more information
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Reactive oxygen species mediate compensatory glomerular hypertrophy in rat uninephrectomized kidney
Published in The journal of physiological sciences (01-09-2009)Get full text
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Withdrawal: Role of extracellular matrix renal tubulo-interstitial nephritis antigen (TINag) in cell survival utilizing integrin αvβ3/focal adhesion kinase (FAK)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B-serine/threonine kinase (AKT) signaling pathway
Published in The Journal of biological chemistry (28-06-2019)Get full text
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NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy
Published in American journal of physiology. Renal physiology (01-06-2005)“…Increased production of reactive oxygen species (ROS) in diabetes may be a common pathway linking diverse pathogenic mechanisms of diabetic vascular…”
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Role of Extracellular Matrix Renal Tubulo-interstitial Nephritis Antigen (TINag) in Cell Survival Utilizing Integrin αvβ3/Focal Adhesion Kinase (FAK)/Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B-Serine/Threonine Kinase (AKT) Signaling Pathway
Published in The Journal of biological chemistry (30-10-2011)“…Tubulo-interstitial nephritis antigen (TINag) is an extracellular matrix protein expressed in tubular basement membranes. Combined mutations in TINag and…”
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Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy
Published in Nephrology, dialysis, transplantation (01-12-2008)“…Background Recent studies showed that angiotensin II type 1 receptor blocker (ARB) slows progression of chronic renal disease in patients with type 2 diabetes,…”
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Low-dose paclitaxel ameliorates renal fibrosis in rat UUO model by inhibition of TGF-β/Smad activity
Published in Laboratory investigation (01-03-2010)“…Transforming growth factor-β (TGF-β) has a pivotal function in the progression of renal fibrosis in a wide variety of renal diseases. Smad proteins have been…”
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