Search Results - "Haruki Fujisawa"
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Studies on anti-rabphilin-3A antibodies in 15 consecutive patients presenting with central diabetes insipidus at a single referral center
Published in Scientific reports (15-03-2022)“…Central diabetes insipidus (CDI) is a rare condition caused by various underlying diseases including inflammatory and autoimmune diseases, and neoplasms…”
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2
Vasopressin escape and memory impairment in a model of chronic syndrome of inappropriate secretion of antidiuretic hormone in mice
Published in ENDOCRINE JOURNAL (01-01-2021)“…Recently, chronic hyponatremia, even mild, has shown to be associated with poor quality of life and high mortality. The mechanism by which hyponatremia…”
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Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus
Published in Internal Medicine (01-02-2022)“…A 21-year-old Japanese man without known diabetes mellitus had abdominal pain. The diagnosis was ketoacidosis and hypertriglyceridemia-induced acute…”
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4
A case of central diabetes insipidus after COVID-19 as a probable diagnosis of lymphocytic infundibulo-neurohypophysitis with positive anti-rabphilin-3A antibodies with review of literature
Published in Endocrine Journal (27-08-2024)“…Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2, and various complications have been reported. Furthermore,…”
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5
Rabphilin-3A as a Targeted Autoantigen in Lymphocytic Infundibulo-neurohypophysitis
Published in The journal of clinical endocrinology and metabolism (01-07-2015)“…Context: Central diabetes insipidus (CDI) can be caused by several diseases, but in about half of the patients the etiological diagnosis remains unknown…”
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Arginine vasopressin deficiency onset after COVID-19 vaccination with positive anti-rabphilin-3A antibodies: a case report and literature review
Published in BMC endocrine disorders (06-08-2024)“…Arginine vasopressin deficiency (AVP-D) can occur due to various conditions, so clarifying its cause is important for deciding treatment strategy. Although…”
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A case of isolated hypothalamitis with a literature review and a comparison with autoimmune hypophysitis
Published in Endocrine Journal (01-01-2021)“…Idiopathic hypothalamitis is a rare condition that can cause anterior pituitary dysfunction and central diabetes insipidus (CDI), occasionally accompanied by a…”
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Impaired Fat Absorption from Intestinal Tract in High-Fat Diet Fed Male Mice Deficient in Proglucagon-Derived Peptides
Published in Nutrients (14-07-2024)“…(1) Background: Proglucagon-derived peptides (PDGPs) including glucagon (Gcg), GLP-1, and GLP-2 regulate lipid metabolism in the liver, adipocytes, and…”
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Mild hyponatremia is associated with low skeletal muscle mass, physical function impairment, and depressive mood in the elderly
Published in BMC geriatrics (06-01-2021)“…Mild hyponatremia (serum sodium 130-135 mEq/L) is a common electrolyte disorder in the elderly. However, its association with both sarcopenia and cognitive…”
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10
Blockade of glucagon increases muscle mass and alters fiber type composition in mice deficient in proglucagon‐derived peptides
Published in Journal of diabetes investigation (01-09-2023)“…ABSTRACT Aims/Introduction Glucagon is secreted from pancreatic α‐cells and plays an important role in amino acid metabolism in liver. Various animal models…”
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11
Two children with lymphocytic hypophysitis presenting with positive anti-rabphilin-3A antibody
Published in Endocrine Journal (01-01-2023)“…Lymphocytic hypophysitis (LYH) is a rare chronic inflammatory disease characterized by lymphocytic infiltration of the anterior or posterior pituitary gland…”
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12
High Protein Diet Feeding Aggravates Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides
Published in Nutrients (25-02-2022)“…(1) Background: Protein stimulates the secretion of glucagon (GCG), which can affect glucose metabolism. This study aimed to analyze the metabolic effect of a…”
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13
Lymphocytic panhypophysitis and anti-rabphilin-3A antibody with pulmonary sarcoidosis
Published in Pituitary (01-04-2022)“…Purpose To explore the clinical significance of anti-rabphillin-3A antibody for the differential diagnosis of lymphocytic panhypophysitis. Methods and results…”
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Central diabetes insipidus with anti-rabphilin-3A antibody positivity causing hypovolemic shock after resection of tumorous lesions in the pelvic cavity
Published in CEN case reports (01-08-2023)“…A 36-year-old female was pointed out to have liver enzyme elevation by routine health checkup. Subsequent contrast-enhanced CT scan identified gigantic uterine…”
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A Pregnant Woman with Excess Vasopressinase-Induced Diabetes Insipidus Complicated by Central Diabetes Insipidus like Lymphocytic Infundibulo-Neurohypophysitis
Published in Case reports in endocrinology (13-04-2024)“…Background. Gestational diabetes insipidus (DI) is a very rare complication of pregnancy. We present a case of gestational DI combining two different types of…”
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16
NMDA receptor antagonist prevents cell death in the hippocampal dentate gyrus induced by hyponatremia accompanying adrenal insufficiency in rats
Published in Experimental neurology (01-01-2017)“…Selective apoptosis of granule cells in the hippocampal dentate gyrus (DG) of rats with bilateral adrenalectomy (ADX) and in patients who died of adrenal…”
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Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons
Published in PloS one (12-10-2016)“…Arginine vasopressin (AVP) is secreted via exocytosis; however, the precise molecular mechanism underlying the exocytosis of AVP remains to be elucidated. To…”
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18
Two children with lymphocytic hypophysitis presenting with positive anti-rabphilin-3A antibody
Published in ENDOCRINE JOURNAL (2023)“…[Abstract.] Lymphocytic hypophysitis (LYH) is a rare chronic inflammatory disease characterized by lymphocytic infiltration of the anterior or posterior…”
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19
A case of isolated hypothalamitis with a literature review and a comparison with autoimmune hypophysitis
Published in ENDOCRINE JOURNAL (2021)“…Abstract. Idiopathic hypothalamitis is a rare condition that can cause anterior pituitary dysfunction and central diabetes insipidus (CDI), occasionally…”
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Journal Article -
20
Effects of hypernatremia on the microglia
Published in Peptides (New York, N.Y. : 1980) (01-09-2024)“…Signs and symptoms of hypernatremia largely indicate central nervous system dysfunction. Acute hypernatremia can cause demyelinating lesions similar to that…”
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