Search Results - "Hartung, Susann"
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The TLR-NF-kB axis contributes to the monocytic inflammatory response against a virulent strain of Lichtheimia corymbifera, a causative agent of invasive mucormycosis
Published in Frontiers in immunology (13-10-2022)“…Invasive mucormycosis (IM) is a life-threatening infection caused by the fungal order Mucorales, its diagnosis is often delayed, and mortality rates range from…”
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The Lipid Raft-Associated Protein Stomatin Is Required for Accumulation of Dectin-1 in the Phagosomal Membrane and for Full Activity of Macrophages against Aspergillus fumigatus
Published in mSphere (21-02-2023)“…Alveolar macrophages belong to the first line of defense against inhaled conidia of the human-pathogenic fungus Aspergillus fumigatus. In lung alveoli, they…”
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Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy
Published in Biomaterials (01-02-2014)“…Abstract Epigenetic silencing of retroviral transgene expression in pluripotent stem cells (PSC) and their differentiated progeny constitutes a major roadblock…”
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Directing cardiomyogenic differentiation of human pluripotent stem cells by plasmid-based transient overexpression of cardiac transcription factors
Published in Stem cells and development (01-04-2013)“…Cardiomyocytes (CMs) derived from human pluripotent stem cells (hPSCs) possess a high potential for regenerative medicine. Previous publications suggested that…”
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Human mucosal-associated invariant T cells respond to Mucorales species in a MR1-dependent manner
Published in Medical mycology (Oxford) (04-05-2021)“…Abstract Activation of mucosal-associated invariant T cells (MAIT cells) by certain bacteria, viruses, and yeast is well studied, but the activation potential…”
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Human MAIT cells are rapidly activated by Aspergillus spp. in an APC‐dependent manner
Published in European journal of immunology (01-10-2018)“…Mucosal associated invariant T cells (MAIT cells) are innate‐like T cells (TC) which are known to be activated by several bacteria and viruses. However,…”
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Fast and Quantitative Evaluation of Human Leukocyte Interaction with Aspergillus fumigatus Conidia by Flow Cytometry
Published in Cytometry. Part A (01-03-2019)“…Systemic infections with the opportunistic mold Aspergillus fumigatus are a great threat to immunocompromised patients such as transplant recipients…”
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Fast and efficient multitransgenic modification of human pluripotent stem cells
Published in Human gene therapy. Part B. Methods (01-04-2014)“…Human pluripotent stem cells (hPSCs) represent a prime cell source for pharmacological research and regenerative therapies because of their extensive expansion…”
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