Hospital usage of antibacterial agents in relation to size and type of hospital and geographical situation

Purpose The objective of this study was to evaluate the level of use and therapy profile of antibacterial agents in hospitals. Further to explore whether type, size or geographical situation influenced antibacterial agents used. Methods Antibacterial use during 1998–1999, in 13 hospitals, including...

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Bibliographic Details
Published in:	Pharmacoepidemiology and drug safety Vol. 14; no. 9; pp. 647 - 649
Main Authors:	Blix, Hege Salvesen, Hartug, Stig
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 01-09-2005
Subjects:	Anti-Bacterial Agents antibacterial patterns antibacterials bed-days drug use Drug Utilization Geography hospitals Hospitals - statistics & numerical data Norway - epidemiology pharmacoepidemiology Retrospective Studies Norway
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Summary:	Purpose The objective of this study was to evaluate the level of use and therapy profile of antibacterial agents in hospitals. Further to explore whether type, size or geographical situation influenced antibacterial agents used. Methods Antibacterial use during 1998–1999, in 13 hospitals, including emergency, referral and university hospitals from all health regions in Norway, were collected retrospectively. Drugs were classified according to the ATC classification and the ATC/DDD index 2001 and standardised bed‐days were used. Results Total annual use varied significantly between hospitals (p < 0.01), mean 47.5 DDD/100 bed‐days. Neither size, type of hospital, nor were geographical situations predictors for total hospital use of antibacterial agents. Therapy patterns were approximately similar all over the country. Beta‐lactamase sensitive penicillins were most frequently used in all hospitals. University hospitals and large hospitals used more 3rd generation cephalosporins. Small hospitals used more penicillins with extended specter. Conclusions Size, type and geographical situation do not influence the level of antibacterial use in Norwegian hospitals. However, therapeutic choice of antibacterial agents differs and seems to be influenced by hospital size and hospital type. Copyright © 2005 John Wiley & Sons, Ltd.
Bibliography:	No conflict of interest was declared. ark:/67375/WNG-LLLQGMC6-Z ArticleID:PDS1080 istex:2761E68B13D361FBEAC29E95173035DC2B6B2427 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1053-8569 1099-1557
DOI:	10.1002/pds.1080