Search Results - "Hartsough, Melanie T."

Nm23-H1 Metastasis Suppressor Phosphorylation of Kinase Suppressor of Ras via a Histidine Protein Kinase Pathway by Hartsough, Melanie T, Morrison, Deborah K, Salerno, Massimiliano, Palmieri, Diane, Ouatas, Taoufik, Mair, Michael, Patrick, Jilma, Steeg, Patricia S

“…The metastasis-suppressive activity of Nm23-H1 was previously correlated with its in vitro histidine protein kinase activity, but physiological substrates have…”
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Nm23/nucleoside diphosphate kinase in human cancers by Hartsough, M T, Steeg, P S

“…Tumor metastasis is the leading cause of death in cancer patients. From a series of tumor cohort studies, low expression of Nm23/NDP kinase has been correlated…”
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Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition by HARTSOUGH, Melanie T, CLARE, Susan E, MAIR, Michael, ELKAHLOUN, Abdel G, SGROI, Dennis, OSBORNE, C. Kent, CLARK, Gary, STEEG, Patricia S

“…We hypothesize that elevation of Nm23-H1 expression in micrometastatic breast cancer cells may inhibit their metastatic colonization and further invasion, and…”
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MMTV-associated transcription factor binding sites increase nm23-H1 metastasis suppressor gene expression in human breast carcinoma cell lines by Ouatas, Taoufik, Clare, Susan E, Hartsough, Melanie T, De La Rosa, Abel, Steeg, Patricia S

“…We hypothesize that elevation of nm23-HI metastasis suppressor gene expression in micrometastatic tumor cells may reduce their subsequent colonization and…”
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Cloning and expression of a rat Smad1: Regulation by TGF and modulation by the ras/MEK pathway by Yue, Jianbo, Hartsough, Melanie T., Frey, Randall S., Frielle, Thomas, Mulder, Kathleen M.

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Transforming Growth Factor-β Signaling in Epithelial Cells by Hartsough, Melanie T., Mulder, Kathleen M.

“…Transforming growth factor (TGF)-β is a potent growth suppressor of epithelial cells. Resistance to TGF-β, however, occurs frequently in solid tumors of…”
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Altered Transforming Growth Factor β Signaling in Epithelial Cells when Ras Activation Is Blocked by Hartsough, Melanie T., Frey, Randall S., Zipfel, Patricia A., Buard, Annie, Cook, Simon J., McCormick, Frank, Mulder, Kathleen M.

“…We have previously demonstrated that growth inhibition of untransformed intestinal epithelial cells by transforming growth factor beta sub(1) (TGF beta ) and…”
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Nm23-H1: Genetic Alterations and Expression Patterns in Tumor Metastasis by Hartsough, Melanie T., Steeg, Patricia S.

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Transforming Growth Factor Activation of p44 in Proliferating Cultures of Epithelial Cells by Melanie T. Hartsough, Kathleen M. Mulder

“…Transforming growth factor-β (TGF-β) is a potent growth inhibitor of a variety of epithelial cell types. The primary signaling mechanism involved in…”
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Wild-type NM23-H1, but not its S120 mutants, suppresses desensitization of muscarinic potassium current by Otero, Angela de S., Doyle, Melissa B., Hartsough, Melanie T., Steeg, Patricia S.

“…NM23 (NDP kinase) modulates the gating of muscarinic K + channels by agonists through a mechanism distinct from GTP regeneration. To better define the function…”
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Cloning and expression of a rat Smad1: Regulation by TGFß and modulation by the ras/MEK pathway by Yue, Jianbo, Hartsough, Melanie T., Frey, Randall S., Frielle, Thomas, Mulder, Kathleen M.

“…A new family of signaling intermediates for TGFß superfamily members and other growth factors has recently been identified and termed Smads. It has been…”
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Altered Transforming Growth Factor β Signaling in Epithelial Cells when Ras Activation Is Blocked by Melanie T. Hartsough, Randall S. Frey, Patricia A. Zipfel, Annie Buard, Simon J. Cook, Frank McCormick, Kathleen M. Mulder

“…We have previously demonstrated that growth inhibition of untransformed intestinal epithelial cells by transforming growth factor β 1 (TGFβ) and TGFβ 2 was…”
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Transforming Growth Factor β Activation of p44mapk in Proliferating Cultures of Epithelial Cells (∗) by Hartsough, Melanie T., Mulder, Kathleen M.

“…Transforming growth factor-β (TGF-β) is a potent growth inhibitor of a variety of epithelial cell types. The primary signaling mechanism involved in mediating…”
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