Search Results - "Hartshorne, G.M."

Oogenesis and cell death in human prenatal ovaries: what are the criteria for oocyte selection? by Hartshorne, G.M., Lyrakou, S., Hamoda, H., Oloto, E., Ghafari, F.

“…Prenatal oogenesis produces hundreds of thousands of oocytes, most of which are discarded through apoptosis before birth. Despite this large-scale selection,…”
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Human immature oocytes grow during culture for IVM by Cavilla, J.L., Kennedy, C.R., Byskov, A.G., Hartshorne, G.M.

“…BACKGROUND Oocyte competence for maturation and embryogenesis is associated with diameter in many mammals. We aimed to test whether this relationship exists in…”
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Influence of p53 and genetic background on prenatal oogenesis and oocyte attrition in mice by Ghafari, F., Pelengaris, S., Walters, E., Hartshorne, G.M.

“…BACKGROUND Meiotic progression, and the number of oocytes surviving to birth, determine the ovarian reserve, yet the control of prenatal oogenesis is poorly…”
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The effects of meiosis activating sterol on in-vitro maturation and fertilization of human oocytes from stimulated and unstimulated ovaries by Cavilla, J.L., Kennedy, C.R., Baltsen, M., Klentzeris, L.D., Byskov, A.G., Hartshorne, G.M.

“…The object of this study was to assess functional maturation in vitro by obtaining data on the fertilization and embryonic competence of human oocytes with or…”
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Five-year study assessing the clinical utility of anti-Müllerian hormone measurements in reproductive-age women with cancer by Palinska-Rudzka, K.E., Ghobara, T., Parsons, N., Milner, J., Lockwood, G., Hartshorne, G.M.

“…An important discussion point before chemotherapy is ovarian toxicity, a side-effect that profoundly affects young women with cancer. Their quality of life…”
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Steroid production by the cumulus: relationship to fertilization in vitro by Hartshorne, G M

“…Insemination media were collected from 92 follicles of 14 patients stimulated to undergo oocyte retrieval for in-vitro fertilization. Levels of progesterone…”
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Who should be offered sperm banking for fertility preservation? A survey of UK oncologists and haematologists by Gilbert, E., Adams, A., Mehanna, H., Harrison, B., Hartshorne, G.M.

“…Fertility after cancer therapy is a significant quality-of-life concern for many patients, their partners and families. Authoritative guidance states that men…”
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Telomere lengths in human oocytes, cleavage stage embryos and blastocysts by Turner, S., Wong, H.P., Rai, J., Hartshorne, G.M.

“…Telomeres are repeated sequences that protect the ends of chromosomes and harbour DNA repair proteins. Telomeres shorten during each cell division in the…”
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Evidence from Human Oocytes for a Genetic Bottleneck in an mtDNA Disease by Marchington, D.R., Macaulay, V., Hartshorne, G.M., Barlow, D., Poulton, J.

“…We have examined oocytes from a patient with Kearn-Sayre syndrome caused by mtDNA rearrangements. In mtDNA diseases, mutant and wild-type mtDNA frequently…”
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Pronuclear orientation, polar body placement, and embryo quality after intracytoplasmic sperm injection and in-vitro fertilization: further evidence for polarity in human oocytes? by Garello, C., Baker, H., Rai, J., Montgomery, S., Wilson, P., Kennedy, C.R., Hartshorne, G.M.

“…Three hypotheses were tested: (i) the distance between first and second polar bodies (PB) may relate to embryo morphology, (ii) that the orientation of…”
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Different perspectives of patients and health care professionals on the potential benefits and risks of blastocyst culture and multiple embryo transfer by Hartshorne, G.M., Lilford, R.J.

“…BACKGROUND: A trade-off exists between the risk of multiple pregnancy and prospects of pregnancy itself in assisted reproduction. Blastocyst culture and embryo…”
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Growth factors promote meiosis in mouse fetal ovaries in vitro by Lyrakou, S., Hultén, M.A., Hartshorne, G.M.

“…Mouse fetal ovaries were cultured to investigate germ cell development in the presence of a combination of the growth factors (GFs) stem cell factor,…”
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O-123. Effects of meiosis-activating sterol (MAS) upon in-vitro maturation and fertilization of oocytes from women with polycystic ovaries by Cavilla, J.L., Kennedy, C.R., Baltsen, M., Byskov, A.G., Hartshorne, G.M.

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Immunocytogenetic detection of normal and abnormal oocytes in human fetal ovarian tissue in culture by Hartshorne, G.M., Barlow, A.L., Child, T.J., Barlow, D.H., Hultén, M.A.

“…This study aimed to: (i) determine whether oocytes are present in cultures of human fetal ovary; (ii) identify whether meiotic anomalies are evident; and (iii)…”
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Relationship between pronuclear orientation, polar body placement and embryo quality after ICSI and IVF by Garello, C., Taylor, H., Marwaha, J., Montgomery, S., Wilson, P., Kennedy, C.R., Hartshorne, G.M.

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P-177. Identification of meiotic cells in cultures of human fetal ovarian tissue by Hartshorne, G.M., Barlow, A., Child, T.J., Kennedy, C.R., Barlow, D.H., Hultén, M.A.

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The influence of in-vitro development upon post-thaw survival and implantation of cryopreserved human blastocysts by Hartshorne, G M, Elder, K, Crow, J, Dyson, H, Edwards, R G

“…Blastocysts from 198 patients were frozen using glycerol as cryoprotectant. No difference in the post-thaw survival of blastocysts or implantation rates was…”
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Effect of cell number at freezing upon survival and viability of cleaving embryos generated from stimulated IVF cycles by Hartshorne, G M, Wick, K, Elder, K, Dyson, H

“…The survival of cleaving embryos after freezing and thawing has been assessed. First, comparisons were made of the proportions of embryos in which all…”
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Meiotic progression of mouse oocytes throughout follicle growth and ovulation in vitro by Hartshorne, G M, Sargent, I L, Barlow, D H

“…Intact ovarian follicles can be grown in culture but the normality of their oocyte development has not yet been established. This work examined meiotic…”
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A simple method for the morphological analysis of human ova: zona penetration in oocytes failing to fertilize or fertilizing abnormally in vitro by Hartshorne, G M

“…A simple and rapid technique is described whereby several unfertilized oocytes and embryos can be processed simultaneously for embedding and sectioning for…”
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