Search Results - "Hartono, Yossa"

Biosynthesis of Nature-Inspired Unnatural Cannabinoids by Lim, Kevin J H, Lim, Yan Ping, Hartono, Yossa D, Go, Maybelle K, Fan, Hao, Yew, Wen Shan

“…Natural products make up a large proportion of medicine available today. Cannabinoids from the plant is one unique class of meroterpenoids that have shown a…”
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Effects of Rho-Associated Kinase (Rock) Inhibitors (Alternative to Y-27632) on Primary Human Corneal Endothelial Cells by Peh, Gary S L, Bandeira, Francisco, Neo, Dawn, Adnan, Khadijah, Hartono, Yossa, Ong, Hon Shing, Naso, Sacha, Venkatraman, Anandalakshmi, Gomes, José A P, Kocaba, Viridiana, Mehta, Jodhbir S

“…(1) Rho-associated coiled-coil protein kinase (ROCK) signaling cascade impacts a wide array of cellular events. For cellular therapeutics, scalable expansion…”
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Cannabinoid Biosynthesis Using Noncanonical Cannabinoid Synthases by Go, Maybelle Kho, Zhu, Tingting, Lim, Kevin Jie Han, Hartono, Yossa Dwi, Xue, Bo, Fan, Hao, Yew, Wen Shan

“…We report enzymes from the berberine bridge enzyme (BBE) superfamily that catalyze the oxidative cyclization of the monoterpene moiety in cannabigerolic acid…”
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Computational study of bindings of HK20 Fab and D5 Fab to HIV-1 gp41 by Hartono, Yossa Dwi, Lazim, Raudah, Yip, Yew Mun, Zhang, Dawei

“…Antibodies HK20 and D5 have been shown to target HIV-1 gp41, thereby inhibiting membrane fusion that facilitates viral entry. The binding picture is static,…”
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Recent Advances in Structure, Function, and Pharmacology of Class A Lipid GPCRs: Opportunities and Challenges for Drug Discovery by Krishna Deepak, R N V, Verma, Ravi Kumar, Hartono, Yossa Dwi, Yew, Wen Shan, Fan, Hao

“…Great progress has been made over the past decade in understanding the structural, functional, and pharmacological diversity of lipid GPCRs. From the first…”
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Computational study of bindings of HL9, a nonapeptide fragment of human lysozyme, to HIV-1 fusion protein gp41 by Hartono, Yossa Dwi, Lee, Angelina Noviani, Lee-Huang, Sylvia, Zhang, Dawei

“…HL9 is a nonapeptide fragment of human lysozyme which has been shown to have anti-HIV-1 activity in nanomolar concentration. This study aims to explain this…”
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Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies by Hartono, Yossa Dwi, Pabon-Martinez, Y. Vladimir, Uyar, Arzu, Wengel, Jesper, Lundin, Karin E, Zain, Rula, Smith, C. I. Edvard, Nilsson, Lennart, Villa, Alessandra

“…Pseudoisocytidine (ΨC) is a synthetic cytidine analogue that can target DNA duplex to form parallel triplex at neutral pH. Pseudoisocytidine has mainly two…”
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Structure-Guided Engineering of Prenyltransferase NphB for High-Yield and Regioselective Cannabinoid Production by Lim, Kevin Jie Han, Hartono, Yossa Dwi, Xue, Bo, Go, Maybelle Kho, Fan, Hao, Yew, Wen Shan

“…Synthetic biology efforts for cannabinoid research have seen a rapid expansion in recent years. This is in response to the increasing awareness and…”
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Computational Study of Uracil Tautomeric Forms in the Ribosome: The Case of Uracil and 5‑Oxyacetic Acid Uracil in the First Anticodon Position of tRNA by Hartono, Yossa Dwi, Ito, Mika, Villa, Alessandra, Nilsson, Lennart

“…Tautomerism is important in many biomolecular interactions, not least in RNA biology. Crystallographic studies show the possible presence of minor tautomer…”
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Modeling pK Shift in DNA Triplexes Containing Locked Nucleic Acids by Hartono, Yossa Dwi, Xu, You, Karshikoff, Andrey, Nilsson, Lennart, Villa, Alessandra

“…The protonation states for nucleic acid bases are difficult to assess experimentally. In the context of DNA triplex, the protonation state of cytidine in the…”
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Modeling p K Shift in DNA Triplexes Containing Locked Nucleic Acids by Hartono, Yossa Dwi, Xu, You, Karshikoff, Andrey, Nilsson, Lennart, Villa, Alessandra

“…The protonation states for nucleic acid bases are difficult to assess experimentally. In the context of DNA triplex, the protonation state of cytidine in the…”
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Adsorption and folding dynamics of MPER of HIV-1 gp41 in the presence of dpc micelle by Hartono, Yossa Dwi, Mun, Yip Yew, Zhang, Dawei

“…Membrane‐proximal ectodomain region (MPER) of HIV‐1 gp41 is known to have several epitopes of monoclonal antibodies. It also plays an important role in the…”
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Effects of Rho-Associated Kinase on Primary Human Corneal Endothelial Cells by Peh, Gary S. L, Bandeira, Francisco, Neo, Dawn, Adnan, Khadijah, Hartono, Yossa, Ong, Hon Shing, Naso, Sacha, Venkatraman, Anandalakshmi, Gomes, José A. P, Kocaba, Viridiana, Mehta, Jodhbir S

“…(1) Rho-associated coiled-coil protein kinase (ROCK) signaling cascade impacts a wide array of cellular events. For cellular therapeutics, scalable expansion…”
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Understanding Structural Features of Biomolecular Interactions : from Classical Simulations to Ab Initio Calculations by Hartono, Yossa Dwi

“…The structures of biomolecules and their interactions dictate their functions. In this thesis, five papers are presented to illustrate how the dynamics of…”
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Molecular dynamics studies of human receptor molecule in hemagglutinin of 1918 and 2009 H1N1 influenza viruses by Lee, Angelina Noviani, Hartono, Yossa Dwi, Sun, Tiedong, Leow, Min Li, Liu, Xue-wei, Huang, Xuri, Zhang, Dawei

“…Molecular dynamics (MD) simulations were carried out to study the behavior of human receptor molecule in the hemagglutinin (HA) of 1918 and 2009 H1N1 influenza…”
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