Search Results - "Hartnett, M Elizabeth"

Pathophysiology and Mechanisms of Severe Retinopathy of Prematurity by Hartnett, M. Elizabeth, MD

“…Retinopathy of prematurity (ROP) affects only premature infants, but as premature births increase in many areas of the world, ROP has become a leading cause of…”
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Mechanisms and Management of Retinopathy of Prematurity by Hartnett, M. Elizabeth, Penn, John S

“…This article reviews retinopathy of prematurity, particularly regarding oxygen use, and describes current and potential therapies based on mechanistic studies…”
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International Classification of Retinopathy of Prematurity, Third Edition by Chiang, Michael F., Quinn, Graham E., Fielder, Alistair R., Ostmo, Susan R., Paul Chan, R.V., Berrocal, Audina, Binenbaum, Gil, Blair, Michael, Peter Campbell, J., Capone, Antonio, Chen, Yi, Dai, Shuan, Ells, Anna, Fleck, Brian W., Good, William V., Hartnett, M. Elizabeth, Holmstrom, Gerd, Kusaka, Shunji, Kychenthal, Andrés, Lepore, Domenico, Lorenz, Birgit, Martinez-Castellanos, Maria Ana, Özdek, Şengül, Ademola-Popoola, Dupe, Reynolds, James D., Shah, Parag K., Shapiro, Michael, Stahl, Andreas, Toth, Cynthia, Vinekar, Anand, Visser, Linda, Wallace, David K., Wu, Wei-Chi, Zhao, Peiquan, Zin, Andrea

“…The International Classification of Retinopathy of Prematurity is a consensus statement that creates a standard nomenclature for classification of retinopathy…”
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Discovering Mechanisms in the Changing and Diverse Pathology of Retinopathy of Prematurity: The Weisenfeld Award Lecture by Hartnett, M Elizabeth

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Venous overload choroidopathy: A hypothetical framework for central serous chorioretinopathy and allied disorders by Spaide, Richard F., Gemmy Cheung, Chui Ming, Matsumoto, Hidetaka, Kishi, Shoji, Boon, Camiel J.F., van Dijk, Elon H.C., Mauget-Faysse, Martine, Behar-Cohen, Francine, Hartnett, M. Elizabeth, Sivaprasad, Sobha, Iida, Tomohiro, Brown, David M., Chhablani, Jay, Maloca, Peter M.

“…In central serous chorioretinopathy (CSC), the macula is detached because of fluid leakage at the level of the retinal pigment epithelium. The fluid appears to…”
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Regulation of signaling events involved in the pathophysiology of neovascular AMD by Wang, Haibo, Hartnett, M Elizabeth

“…Neovascular age-related macular degeneration (AMD) is a complex disease in which an individual's genetic predisposition is affected by aging and environmental…”
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RNA-Seq Provides Insights into VEGF-Induced Signaling in Human Retinal Microvascular Endothelial Cells: Implications in Retinopathy of Prematurity by Ramshekar, Aniket, Bretz, Colin A, Hartnett, M Elizabeth

“…The pathophysiology of retinopathy of prematurity (ROP) is postulated to first involve delayed intraretinal vascularization, followed by intravitreal…”
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7-ketocholesterol induces endothelial-mesenchymal transition and promotes fibrosis: implications in neovascular age-related macular degeneration and treatment by Wang, Haibo, Ramshekar, Aniket, Kunz, Eric, Hartnett, M. Elizabeth

“…Oxidized cholesterols and lipids accumulate in Bruch’s membrane in age-related macular degeneration (AMD). It remains unknown what causal relationship exists…”
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Laser versus Anti-VEGF: A Paradigm Shift for Treatment-Warranted Retinopathy of Prematurity by Hartnett, M. Elizabeth, Stahl, Andreas

“…Retinopathy of prematurity (ROP), a leading cause of childhood blindness, has historically been associated with blindness from overgrowth of blood vessels from…”
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Vascular Endothelial Growth Factor Antagonist Therapy for Retinopathy of Prematurity by Hartnett, M. Elizabeth, MD

“…In this article, the growing problem of retinopathy of prematurity (ROP) worldwide, treatments for severe ROP including standard-of-care laser treatment, and…”
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Thy-1 Regulates VEGF-Mediated Choroidal Endothelial Cell Activation and Migration: Implications in Neovascular Age-Related Macular Degeneration by Wang, Haibo, Han, Xiaokun, Kunz, Eric, Hartnett, M Elizabeth

“…This study addresses the hypothesis that age-related stresses upregulate Thy-1 in choroidal endothelial cells (CECs) and contribute to CEC activation and…”
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Vascular Endothelial Growth Factor Signaling in Models of Oxygen-Induced Retinopathy: Insights Into Mechanisms of Pathology in Retinopathy of Prematurity by Ramshekar, Aniket, Hartnett, M Elizabeth

“…Retinopathy of prematurity (ROP) is a leading cause of blindness in children worldwide. Blindness can occur from retinal detachment caused by pathologic…”
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The effects of oxygen stresses on the development of features of severe retinopathy of prematurity: knowledge from the 50/10 OIR model by Elizabeth Hartnett, M.

“…The objective of this study is to determine growth factor expression and activation of signaling pathways associated with intravitreous neovascularization and…”
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Targeted Knockdown of Overexpressed VEGFA or VEGF164 in Müller cells maintains retinal function by triggering different signaling mechanisms by Becker, Silke, Wang, Haibo, Simmons, Aaron B., Suwanmanee, Thipparat, Stoddard, Gregory J., Kafri, Tal, Hartnett, M. Elizabeth

“…Oxygen-induced retinopathy (OIR) upregulates Müller cell vascular endothelial growth factor A (VEGFA) that causes intravitreal neovascularization similar to…”
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The Effects of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase and Erythropoietin, and Their Interactions in Angiogenesis: Implications in Retinopathy of Prematurity by Cung, Thaonhi, Wang, Haibo, Hartnett, M. Elizabeth

“…Retinopathy of prematurity (ROP) is a leading cause of vision impairment and blindness in premature infants. Oxidative stress is implicated in its…”
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Anti-VEGF antibody leads to later atypical intravitreous neovascularization and activation of angiogenic pathways in a rat model of retinopathy of prematurity by McCloskey, Manabu, Wang, Haibo, Jiang, Yanchao, Smith, George Wesley, Strange, Jeremy, Hartnett, M Elizabeth

“…Inhibiting VEGF improves adult retino/choroido-vascular diseases, but can lead to recurrent intravitreous neovascularization (IVNV), avascular retina (AVA),…”
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Effects of oxygen on the development and severity of retinopathy of prematurity by Hartnett, M. Elizabeth, MD, Lane, Robert H., MD, MS

“…Summary In 1942, when retinopathy of prematurity (ROP) first manifested as retrolental fibroplasia, the technology to monitor or regulate oxygen did not exist,…”
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The value of pre-symptomatic genetic risk assessment for age-related macular degeneration: the Moran AMD Genetic Testing Assessment (MAGENTA) study-a study protocol for a randomized controlled trial by Addo, Emmanuel K, Hartnett, M Elizabeth, Bernstein, Paul S

“…Age-related macular degeneration (AMD) is an irreversible blinding eye condition with complex genetic and environmental etiologies. Genetic testing for AMD for…”
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Characterization of Retinal Structure in ATF6-Associated Achromatopsia by Mastey, Rebecca R, Georgiou, Michalis, Langlo, Christopher S, Kalitzeos, Angelos, Patterson, Emily J, Kane, Thomas, Singh, Navjit, Vincent, Ajoy, Moore, Anthony T, Tsang, Stephen H, Lin, Jonathan H, Young, Marielle P, Hartnett, M Elizabeth, Héon, Elise, Kohl, Susanne, Michaelides, Michel, Carroll, Joseph

“…Mutations in six genes have been associated with achromatopsia (ACHM): CNGA3, CNGB3, PDE6H, PDE6C, GNAT2, and ATF6. ATF6 is the most recent gene to be…”
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Short-term Outcomes After Very Low-Dose Intravitreous Bevacizumab for Retinopathy of Prematurity by Wallace, David K, Kraker, Raymond T, Freedman, Sharon F, Crouch, Eric R, Bhatt, Amit R, Hartnett, M Elizabeth, Yang, Michael B, Rogers, David L, Hutchinson, Amy K, VanderVeen, Deborah K, Haider, Kathryn M, Siatkowski, R Michael, Dean, Trevano W, Beck, Roy W, Repka, Michael X, Smith, Lois E, Good, William V, Kong, Lingkun, Cotter, Susan A, Holmes, Jonathan M

“…Intravitreous bevacizumab (0.25 mg to 0.625 mg) is commonly used to treat type 1 retinopathy of prematurity (ROP), but there are concerns about systemic…”
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