Search Results - "Hartner, Franz S"

New opportunities by synthetic biology for biopharmaceutical production in Pichia pastoris by Vogl, Thomas, Hartner, Franz S, Glieder, Anton

“…Graphical abstract Highlights ► The application of Pichia pastoris for biopharmaceutical production is described. ► Synthetic biology approaches and…”
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Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology by Näätsaari, Laura, Mistlberger, Beate, Ruth, Claudia, Hajek, Tanja, Hartner, Franz S, Glieder, Anton

“…Targeted gene replacement to generate knock-outs and knock-ins is a commonly used method to study the function of unknown genes. In the methylotrophic yeast…”
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Regulation of methanol utilisation pathway genes in yeasts by Hartner, Franz S, Glieder, Anton

“…Methylotrophic yeasts such as Candida boidinii, Hansenula polymorpha, Pichia methanolica and Pichia pastoris are an emerging group of eukaryotic hosts for…”
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Engineering Pichia pastoris for improved NADH regeneration: A novel chassis strain for whole-cell catalysis by Geier, Martina, Brandner, Christoph, Strohmeier, Gernot A, Hall, Mélanie, Hartner, Franz S, Glieder, Anton

“…Many synthetically useful reactions are catalyzed by cofactor-dependent enzymes. As cofactors represent a major cost factor, methods for efficient cofactor…”
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Promoter library designed for fine-tuned gene expression in Pichia pastoris by Hartner, Franz S., Ruth, Claudia, Langenegger, David, Johnson, Sabrina N., Hyka, Petr, Lin-Cereghino, Geoffrey P., Lin-Cereghino, Joan, Kovar, Karin, Cregg, James M., Glieder, Anton

“…Although frequently used as protein production host, there is only a limited set of promoters available to drive the expression of recombinant proteins in…”
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Real-time PCR-based determination of gene copy numbers in Pichia pastoris by Abad, Sandra, Kitz, Kerstin, Hörmann, Astrid, Schreiner, Ulrike, Hartner, Franz S., Glieder, Anton

“…Pichia pastoris is a preferred host for heterologous protein production. Expression cassettes are usually integrated into the genome of this methylotrophic…”
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Investigation of lipase-catalyzed Michael-type carbon–carbon bond formations by Strohmeier, Gernot A., Sović, Tanja, Steinkellner, Georg, Hartner, Franz S., Andryushkova, Aleksandra, Purkarthofer, Thomas, Glieder, Anton, Gruber, Karl, Griengl, Herfried

“…Conjugate additions of carbon nucleophiles to appropriate acceptor molecules were investigated with respect to the synthetic potential and stereochemistry of…”
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Enhancing stress resistance and production phenotypes through transcriptome engineering by Lam, Felix H, Hartner, Franz S, Fink, Gerald R, Stephanopoulos, Gregory

“…As Saccharomyces cerevisiae is engineered further as a microbial factory for industrially relevant but potentially cytotoxic molecules such as ethanol, issues…”
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Pichia pastoris 'just in time' alternative respiration by Kern, Alexander, Hartner, Franz S, Freigassner, Maria, Spielhofer, Julia, Rumpf, Cornelia, Leitner, Laura, Frohlich, Kai-Uwe, Glieder, Anton

“…1 Institute for Molecular Biotechnology, Graz University of Technology, Petersgasse 14/2, A-8010 Graz, Austria 2 Institute for Molecular Biosciences,…”
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Screening hydroxynitrile lyases for ( R)-pantolactone synthesis by Pscheidt, Beate, Avi, Manuela, Gaisberger, Richard, Hartner, Franz S., Skranc, Wolfgang, Glieder, Anton

“…The application of ( R)-hydroxynitrile lyases (( R)-HNLs) enables a simple chemo-enzymatic approach towards ( R)-pantolactone synthesis. For the first time,…”
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