Search Results - "Hartmann, W"
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Coherent modulation up to 100 GBd 16QAM using silicon-organic hybrid (SOH) devices
Published in Optics express (08-01-2018)“…We demonstrate the generation of higher-order modulation formats using silicon-based inphase/quadrature (IQ) modulators at symbol rates of up to 100 GBd. Our…”
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Martian cratering 11. Utilizing decameter scale crater populations to study Martian history
Published in Meteoritics & planetary science (01-03-2017)“…New information has been obtained in recent years regarding formation rates and the production size‐frequency distribution (PSFD) of decameter‐scale primary…”
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Bondi–Hoyle–Littleton accretion and the upper-mass stellar initial mass function
Published in Monthly notices of the Royal Astronomical Society (01-09-2015)“…We report on a series of numerical simulations of gas clouds with self-gravity forming sink particles, adopting an isothermal equation of state to isolate the…”
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Accretion in Evolved and Transitional Disks in CEP OB2: Looking for the Origin of the Inner Holes
Published in The Astrophysical journal (10-02-2010)“…We present accretion rates for a large number of solar-type stars in the Cep OB2 region, based on U-band observations. Our study comprises 95 members of the…”
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Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer–Soft Tissue and Bone Sarcoma Group (EORTC–STBSG) recommendations for pathological examination and reporting
Published in European journal of cancer (1990) (01-01-2016)“…Abstract At present, there is not a commonly used and generally accepted standardized approach for the pathologic evaluation of pretreated soft tissue…”
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Gravity or turbulence? - II. Evolving column density probability distribution functions in molecular clouds
Published in Monthly notices of the Royal Astronomical Society (01-09-2011)“…It has been recently shown that molecular clouds do not exhibit a unique shape for the column density probability distribution function (N-PDF). Instead,…”
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Cooling, Gravity, and Geometry: Flow-driven Massive Core Formation
Published in The Astrophysical journal (10-02-2008)“…We study numerically the formation of molecular clouds in large-scale colliding flows including self-gravity. The models emphasize the competition between the…”
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Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors
Published in PloS one (27-03-2014)“…The Dyrk family of protein kinases is implicated in the pathogenesis of several diseases, including cancer and neurodegeneration. Pharmacological inhibitors…”
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Superficial fibromas with CTNNB1 mutation
Published in Genes chromosomes & cancer (01-05-2024)“…Superficial fibromas are a group of mesenchymal spindle cell lesions with pathomorphological heterogeneity and diverse molecular backgrounds. In part, they may…”
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Cushing’s Syndrome: Development of Highly Potent and Selective CYP11B1 Inhibitors of the (Pyridylmethyl)pyridine Type
Published in Journal of medicinal chemistry (08-08-2013)“…Potent and selective CYP11B1 inhibitors could be promising therapeutics for the treatment of Cushing’s syndrome. Optimization of Ref 1…”
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Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors
Published in Journal of the American Chemical Society (03-10-2012)“…2-Heptyl-4-hydroxyquinoline (HHQ) and Pseudomonas quinolone signal (PQS) are involved in the regulation of virulence factor production and biofilm formation in…”
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Structure and expansion law of H ii regions in structured molecular clouds
Published in Monthly notices of the Royal Astronomical Society (01-08-2019)“…Abstract We present radiation-magnetohydrodynamic simulations aimed at studying evolutionary properties of H ii regions in turbulent, magnetized, and…”
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The Birth of Molecular Clouds: Formation of Atomic Precursors in Colliding Flows
Published in The Astrophysical journal (10-09-2006)“…Molecular cloud complexes (MCCs)are highly structured and "turbulent." Observational evidence suggests that MCCs are dynamically dominated systems, rather than…”
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PD-1 checkpoint blockade in patients with relapsed AML after allogeneic stem cell transplantation
Published in Bone marrow transplantation (Basingstoke) (01-02-2017)Get full text
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In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor Treatment
Published in Frontiers in microbiology (24-05-2017)“…is a Gram-negative bacterium, which causes opportunistic infections in immuno-compromised individuals. Due to its multiple resistances toward antibiotics, the…”
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Formation of Structure in Molecular Clouds: A Case Study
Published in The Astrophysical journal (10-11-2005)“…Molecular clouds (MCs) are highly structured and turbulent. Colliding gas streams of atomic hydrogen have been suggested as a possible source of MCs,…”
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3-Pyridyl substituted aliphatic cycles as CYP11B2 inhibitors: aromaticity abolishment of the core significantly increased selectivity over CYP1A2
Published in PloS one (01-11-2012)“…Aldosterone synthase (CYP11B2) is a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone levels. On…”
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Fragmentation of Shocked Flows: Gravity, Turbulence, and Cooling
Published in The Astrophysical journal (20-08-2008)“…The observed rapid onset of star formation in molecular clouds requires rapid formation of dense fragments that can collapse individually before being…”
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The relationship between nursing home quality and costs: Evidence from the VA
Published in PloS one (19-09-2018)“…Ensuring quality of care in nursing homes is a public health priority, yet how nursing home quality relates to cost is not well understood. This paper…”
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Recent progress in pharmaceutical therapies for castration-resistant prostate cancer
Published in International Journal of Molecular Sciences (04-07-2013)“…Since 2010, six drugs have been approved for the treatment of castration-resistant prostate cancer, i.e., CYP17 inhibitor Abiraterone, androgen receptor…”
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