Search Results - "Hartmann, Phillipp"

Editorial: The Microbiome in Hepatobiliary and Intestinal Disease by Hartmann, Phillipp

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Alcoholic Liver Disease: The Gut Microbiome and Liver Cross Talk by Hartmann, Phillipp, Seebauer, Caroline T., Schnabl, Bernd

“…Alcoholic liver disease (ALD) is a leading cause of morbidity and mortality worldwide. Alcoholic fatty liver disease can progress to steatohepatitis, alcoholic…”
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Liver cirrhosis and immune dysfunction by Hasa, Elda, Hartmann, Phillipp, Schnabl, Bernd

“…Abstract Cirrhosis is end-stage liver disease resulting from various etiologies and is a common cause of death worldwide. The progression from compensated to…”
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How to calculate sample size in animal and human studies by Zhang, Xinlian, Hartmann, Phillipp

“…One of the most important statistical analyses when designing animal and human studies is the calculation of the required sample size. In this review, we…”
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Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation by Wang, Lirui, Fouts, Derrick E., Stärkel, Peter, Hartmann, Phillipp, Chen, Peng, Llorente, Cristina, DePew, Jessica, Moncera, Kelvin, Ho, Samuel B., Brenner, David A., Hooper, Lora V., Schnabl, Bernd

“…Approximately half of all deaths from liver cirrhosis, the tenth leading cause of mortality in the United States, are related to alcohol use. Chronic alcohol…”
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Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice by Hartmann, Phillipp, Hochrath, Katrin, Horvath, Angela, Chen, Peng, Seebauer, Caroline T., Llorente, Cristina, Wang, Lirui, Alnouti, Yazen, Fouts, Derrick E., Stärkel, Peter, Loomba, Rohit, Coulter, Sally, Liddle, Christopher, Yu, Ruth T., Ling, Lei, Rossi, Stephen J., DePaoli, Alex M., Downes, Michael, Evans, Ronald M., Brenner, David A., Schnabl, Bernd

“…Alcoholic liver disease (ALD) is associated with changes in the intestinal microbiota. Functional consequences of alcohol‐associated dysbiosis are largely…”
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Toll-Like Receptor 2–Mediated Intestinal Injury and Enteric Tumor Necrosis Factor Receptor I Contribute to Liver Fibrosis in Mice by Hartmann, Phillipp, Haimerl, Michael, Mazagova, Magdalena, Brenner, David A, Schnabl, Bernd

“…Background & Aims Progression of liver fibrosis in experimental models depends on gut-derived bacterial products, but little is known about mechanisms of…”
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Inexpensive, Accurate, and Stable Method to Quantitate Blood Alanine Aminotransferase (ALT) Levels by Hartmann, Phillipp, Schnabl, Bernd

“…Alanine aminotransferase (ALT) levels are frequently determined in serum and plasma samples and are a primary measure to quantitate hepatocellular injury in…”
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Dynamic Changes of the Fungal Microbiome in Alcohol Use Disorder by Hartmann, Phillipp, Lang, Sonja, Zeng, Suling, Duan, Yi, Zhang, Xinlian, Wang, Yanhan, Bondareva, Marina, Kruglov, Andrey, Fouts, Derrick E, Stärkel, Peter, Schnabl, Bernd

“…Alcohol-associated liver disease (ALD) is an important cause of morbidity and mortality worldwide. The intestinal microbiota is involved in the development and…”
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Deficiency of intestinal mucin‐2 ameliorates experimental alcoholic liver disease in mice by Hartmann, Phillipp, Chen, Peng, Wang, Hui J., Wang, Lirui, McCole, Declan F., Brandl, Katharina, Stärkel, Peter, Belzer, Clara, Hellerbrand, Claus, Tsukamoto, Hidekazu, Ho, Samuel B., Schnabl, Bernd

“…The intestinal mucus layer protects the epithelium from noxious agents, viruses, and pathogenic bacteria present in the gastrointestinal tract. It is composed…”
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Fecal cytolysin does not predict disease severity in acutely decompensated cirrhosis and acute-on-chronic liver failure by Hartmann, Phillipp, Lang, Sonja, Schierwagen, Robert, Klein, Sabine, Praktiknjo, Michael, Trebicka, Jonel, Schnabl, Bernd

“…Cirrhosis with acute decompensation (AD) and acute-on-chronic liver failure (ACLF) are characterized by high morbidity and mortality. Cytolysin, a toxin from…”
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Fecal gelatinase does not predict mortality in patients with alcohol-associated hepatitis by Yang, Yongqiang, Hartmann, Phillipp, Schnabl, Bernd

“…Alcohol-associated liver disease is highly prevalent worldwide, with alcohol-associated hepatitis as a severe form characterized by substantial morbidity,…”
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Colesevelam ameliorates non-alcoholic steatohepatitis and obesity in mice by Hartmann, Phillipp, Duan, Yi, Miyamoto, Yukiko, Demir, Münevver, Lang, Sonja, Hasa, Elda, Stern, Patrick, Yamashita, Dennis, Conrad, Mary, Eckmann, Lars, Schnabl, Bernd

“…Background Obesity, non-alcoholic fatty liver disease (NAFLD) and its more advanced form non-alcoholic steatohepatitis (NASH) are important causes of morbidity…”
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Fungal signature differentiates alcohol-associated liver disease from nonalcoholic fatty liver disease by Viebahn, Greta, Hartmann, Phillipp, Lang, Sonja, Demir, Münevver, Zhang, Xinlian, Fouts, Derrick E, Stärkel, Peter, Schnabl, Bernd

“…The fungal microbiota plays an important role in the pathogenesis of alcohol-associated liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD). In…”
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Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity by Hartmann, Phillipp, Seebauer, Caroline T, Mazagova, Magdalena, Horvath, Angela, Wang, Lirui, Llorente, Cristina, Varki, Nissi M, Brandl, Katharina, Ho, Samuel B, Schnabl, Bernd

“…Nonalcoholic fatty liver disease (NAFLD) and obesity are characterized by altered gut microbiota, inflammation, and gut barrier dysfunction. Here, we…”
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The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease by Hartmann, Phillipp, Chen, Wei-Chung, Schnabl, Bernd

“…Alcoholic liver disease (ALD) encompasses hepatic steatosis, which may progress to alcoholic hepatitis, fibrosis, and cirrhosis. It remains a leading cause of…”
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Intestinal virome in patients with alcohol use disorder and after abstinence by Hsu, Cynthia L., Zhang, Xinlian, Jiang, Lu, Lang, Sonja, Hartmann, Phillipp, Pride, David, Fouts, Derrick E., Stärkel, Peter, Schnabl, Bernd

“…Alcohol use is a leading cause of chronic liver disease worldwide, and changes in the microbiome associated with alcohol use contribute to patients’ risk for…”
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Do Glucagon-like Peptide Receptor Agonists Cause Postendoscopic Aspiration Pneumonia? by Hartmann, Phillipp

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Malassezia restricta promotes alcohol-induced liver injury by Zeng, Suling, Hartmann, Phillipp, Park, Minji, Duan, Yi, Lang, Sonja, Llorente, Cristina, Wang, Yanhan, Cabré, Noemí, Fouts, Derrick E, Bacher, Petra, Jung, Won Hee, Stärkel, Peter, Schnabl, Bernd

“…Chronic alcohol consumption is associated with intestinal fungal dysbiosis, yet we understand little about how alterations of intestinal fungi (mycobiota)…”
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Fungal infections and the fungal microbiome in hepatobiliary disorders by Hartmann, Phillipp, Schnabl, Bernd

“…Liver and biliary diseases affect more than a billion people worldwide, with high associated morbidity and mortality. The impact of the intestinal bacterial…”
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