Search Results - "Hartmann, Laura"

Recent Developments in Solid‐Phase Strategies towards Synthetic, Sequence‐Defined Macromolecules by Hill, Stephen A., Gerke, Christoph, Hartmann, Laura

“…Sequence‐control in synthetic polymers is an important contemporary research area because it provides the opportunity to create completely novel materials for…”
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Sequence-Controlled Glycopolymers via Step-Growth Polymerization of Precision Glycomacromolecules for Lectin Receptor Clustering by Gerke, Christoph, Ebbesen, Morten F, Jansen, Dennis, Boden, Sophia, Freichel, Tanja, Hartmann, Laura

“…A versatile approach for the synthesis of sequence-controlled multiblock copolymers, using a combination of solid phase synthesis and step-growth…”
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Sequence‐Defined Introduction of Hydrophobic Motifs and Effects in Lectin Binding of Precision Glycomacromolecules by Boden, Sophia, Reise, Franziska, Kania, Jessica, Lindhorst, Thisbe K., Hartmann, Laura

“…This study investigates the influence of an increasingly hydrophobic backbone of multivalent glycomimetics based on sequence‐defined oligo(amidoamines) on…”
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Sequence-defined positioning of amine and amide residues to control catechol driven wet adhesion by Fischer, Lukas, Strzelczyk, Alexander K, Wedler, Nils, Kropf, Christian, Schmidt, Stephan, Hartmann, Laura

“…Catechol and amine residues, both abundantly present in mussel adhesion proteins, are known to act cooperatively by displacing hydration barriers before…”
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Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans by Broecker, Felix, Hanske, Jonas, Martin, Christopher E., Baek, Ju Yuel, Wahlbrink, Annette, Wojcik, Felix, Hartmann, Laura, Rademacher, Christoph, Anish, Chakkumkal, Seeberger, Peter H.

“…Synthetic cell-surface glycans are promising vaccine candidates against Clostridium difficile . The complexity of large, highly antigenic and immunogenic…”
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Quantitative mapping of glycoprotein micro-heterogeneity and macro-heterogeneity: an evaluation of mass spectrometry signal strengths using synthetic peptides and glycopeptides by Stavenhagen, Kathrin, Hinneburg, Hannes, Thaysen-Andersen, Morten, Hartmann, Laura, Silva, Daniel Varón, Fuchser, Jens, Kaspar, Stephanie, Rapp, Erdmann, Seeberger, Peter H., Kolarich, Daniel

“…Mass spectrometry (MS) is used to quantify the relative distribution of glycans attached to particular protein glycosylation sites (micro‐heterogeneity) and…”
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Mesoporous Protein Particles Through Colloidal CaCO3 Templates by Schmidt, Stephan, Behra, Muriel, Uhlig, Katja, Madaboosi, Narayanan, Hartmann, Laura, Duschl, Claus, Volodkin, Dmitry

“…Porous colloidal particles can be tailored using templating techniques to maximize their effectiveness for a wide range of applications, including separation,…”
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Controlling the Surface Functionalization of Ultrasmall Gold Nanoparticles by Sequence‐Defined Macromolecules by Meer, Selina Beatrice, Seiler, Theresa, Buchmann, Christin, Partalidou, Georgia, Boden, Sophia, Loza, Kateryna, Heggen, Marc, Linders, Jürgen, Prymak, Oleg, Oliveira, Cristiano L. P., Hartmann, Laura, Epple, Matthias

“…Ultrasmall gold nanoparticles (diameter about 2 nm) were surface‐functionalized with cysteine‐carrying precision macromolecules. These consisted of…”
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Segmentation of German Consumers Based on Perceived Dimensions of Luxury Food by Hartmann, Laura Helena, Nitzko, Sina, Spiller, Achim

“…Recent trends in the German food sector have shifted and segmented consumer consumption motives toward indulgence, quality, and sustainability. Simultaneously,…”
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Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa by Joachim, Ines, Rikker, Sebastian, Hauck, Dirk, Ponader, Daniela, Boden, Sophia, Sommer, Roman, Hartmann, Laura, Titz, Alexander

“…Infections with the Gram-negative bacterium Pseudomonas aeruginosa result in a high mortality among immunocompromised patients and those with cystic fibrosis…”
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Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines by Hartmann, Laura, Schröter, Philipp, Osen, Wolfram, Baumann, Daniel, Offringa, Rienk, Moustafa, Mahmoud, Will, Rainer, Debus, Jürgen, Brons, Stephan, Rieken, Stefan, Eichmüller, Stefan B.

“…While for photon radiation hypofractionation has been reported to induce enhanced immunomodulatory effects, little is known about the immunomodulatory…”
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Facile Synthesis of Catechol-Containing Polyacrylamide Copolymers: Synergistic Effects of Amine, Amide and Catechol Residues in Mussel-Inspired Adhesives by Bonda, Lorand, Müller, Janita, Fischer, Lukas, Löwe, Maryna, Kedrov, Alexej, Schmidt, Stephan, Hartmann, Laura

“…The straightforward synthesis of polyamide-derived statistical copolymers with catechol, amine, amide and hydroxy residues via free radical polymerization is…”
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Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation by Veinalde, Rūta, Grossardt, Christian, Hartmann, Laura, Bourgeois-Daigneault, Marie-Claude, Bell, John C., Jäger, Dirk, von Kalle, Christof, Ungerechts, Guy, Engeland, Christine E.

“…Combination of oncolytic virotherapy with immunomodulators is emerging as a promising therapeutic strategy for numerous tumor entities. In this study, we…”
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Presenting Precision Glycomacromolecules on Gold Nanoparticles for Increased Lectin Binding by Boden, Sophia, Wagner, Kristina G, Karg, Matthias, Hartmann, Laura

“…Glyco-functionalized gold nanoparticles have great potential as biosensors and as inhibitors due to their increased binding to carbohydrate-recognizing…”
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Synthesis of Porphyrin and Bacteriochlorin Glycoconjugates through CuAAC Reaction Tuning by Bennion, Matthew C., Burch, Morgan A., Dennis, David G., Lech, Melissa E., Neuhaus, Kira, Fendler, Nikole L., Parris, Matthew R., Cuadra, Jessica E., Dixon, Charlie F., Mukosera, George T., Blauch, David N., Hartmann, Laura, Snyder, Nicole L., Ruppel, Joshua V.

“…Rapid and reproducible access to a series of unique porphyrin and bacteriochlorin glycoconjugates, including meso‐glycosylated porphyrins and bacteriochlorins,…”
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Immunological Effects and Viral Gene Expression Determine the Efficacy of Oncolytic Measles Vaccines Encoding IL-12 or IL-15 Agonists by Backhaus, Paul S., Veinalde, Rūta, Hartmann, Laura, Dunder, Jessica E., Jeworowski, Lara M., Albert, Jessica, Hoyler, Birgit, Poth, Tanja, Jäger, Dirk, Ungerechts, Guy, Engeland, Christine E.

“…Tumor-targeted immunomodulation using oncolytic viral vectors is currently being investigated as a promising strategy in cancer therapy. In a previous study,…”
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Mechanical Carbohydrate Sensors Based on Soft Hydrogel Particles by Pussak, Daniel, Ponader, Daniela, Mosca, Simone, Ruiz, Salomé Vargas, Hartmann, Laura, Schmidt, Stephan

“…Elastic sensors: A simple method is presented for the measurement of specific biomolecular interactions with soft colloidal hydrogel particles (SCPs) as…”
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Glycans Controlling Virus Infections: Meeting Report on the 1st International Symposium on Glycovirology Schöntal, Germany, 02⁻04 May 2018 by Stehle, Thilo, Peters, Thomas, Hartmann, Laura, Schelhaas, Mario

“…Glycans are, with nucleic acids, proteins and lipids, one of the four founding structures of cellular life. Due to their non-template synthesis, they are…”
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Probing multivalency in ligand-receptor-mediated adhesion of soft, biomimetic interfaces by Schmidt, Stephan, Wang, Hanqing, Pussak, Daniel, Mosca, Simone, Hartmann, Laura

“…Many biological functions at cell level are mediated by the glycocalyx, a dense carbohydrate-presenting layer. In this layer specific interactions between…”
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Morphology of Photopolymerized End-Linked Poly(ethylene glycol) Hydrogels by Small-Angle X-ray Scattering by Waters, Dale J, Engberg, Kristin, Parke-Houben, Rachel, Hartmann, Laura, Ta, Christopher N, Toney, Michael F, Frank, Curtis W

“…Because of the biocompatibility of poly(ethylene glycol) (PEG), PEG-based hydrogels have attracted considerable interest for use as biomaterials in tissue…”
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