Search Results - "Hartmann, Elena"

9p24.1 alterations and programmed cell death 1 ligand 1 expression in early stage unfavourable classical Hodgkin lymphoma: an analysis from the German Hodgkin Study Group NIVAHL trial by Gerhard‐Hartmann, Elena, Goergen, Helen, Bröckelmann, Paul J., Mottok, Anja, Steinmüller, Tabea, Grund, Johanna, Zamò, Alberto, Ben‐Neriah, Susana, Sasse, Stephanie, Borchmann, Sven, Fuchs, Michael, Borchmann, Peter, Reinke, Sarah, Engert, Andreas, Veldman, Johanna, Diepstra, Arjan, Klapper, Wolfram, Rosenwald, Andreas

“…Summary High programmed cell death 1 ligand 1 (PD‐L1) protein expression and copy number alterations (CNAs) of the corresponding genomic locus 9p24.1 in…”
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Epstein–Barr virus infection patterns in nodular lymphocyte‐predominant Hodgkin lymphoma by Gerhard‐Hartmann, Elena, Jöhrens, Korinna, Schinagl, Lisa‐Marie, Zamó, Alberto, Rosenwald, Andreas, Anagnostopoulos, Ioannis, Rosenfeldt, Mathias

“…Aims To investigate Epstein‐Barr virus (EBV) latency types in 19 cases of EBV‐positive nodular lymphocyte‐predominant Hodgkin lymphoma (NLPHL), as such…”
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Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study by Burger, Jan A, Dr, Keating, Michael J, Prof, Wierda, William G, Prof, Hartmann, Elena, MD, Hoellenriegel, Julia, MS, Rosin, Nathalie Y, PhD, de Weerdt, Iris, MD, Jeyakumar, Ghayathri, MD, Ferrajoli, Alessandra, MD, Cardenas-Turanzas, Marylou, PhD, Lerner, Susan, MS, Jorgensen, Jeffrey L, MD, Nogueras-González, Graciela M, MS, Zacharian, Gracy, MS, Huang, Xuelin, PhD, Kantarjian, Hagop, Prof, Garg, Naveen, MD, Rosenwald, Andreas, Prof, O'Brien, Susan, Prof

“…Summary Background Ibrutinib, an orally administered covalent inhibitor of Bruton's tyrosine kinase (BTK), is an effective treatment for relapsed chronic…”
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Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1 by Kohlhaas, Vivien, Blakemore, Stuart James, Al-Maarri, Mona, Nickel, Nadine, Pal, Martin, Roth, Andreas, Hövelmeyer, Nadine, Schäfer, Stephan C., Knittel, Gero, Lohneis, Philipp, Nikolic, Milos, Wiederstein, Janica L., Franitza, Marek, Georgomonolis, Theodoros, Reinart, Nina, Herling, Marco, Herling, Carmen, Hartmann, Elena M., Rosenwald, Andreas, Klapper, Wolfram, Büttner, Reinhard, Moia, Riccardo, Rossi, Davide, Boldorini, Renzo, Gaidano, Gianluca, Frenzel, Lukas P., Reinhardt, Hans Christian, Brüning, Jens C., Hallek, Michael, Krüger, Marcus, Peifer, Martin, Pallasch, Christian P., Wunderlich, F. Thomas

“…Richter’s transformation (RT) is an aggressive lymphoma that occurs upon progression from chronic lymphocytic leukemia (CLL). Transformation has been…”
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CCND2 rearrangements are the most frequent genetic events in cyclin D1− mantle cell lymphoma by Salaverria, Itziar, Royo, Cristina, Carvajal-Cuenca, Alejandra, Clot, Guillem, Navarro, Alba, Valera, Alejandra, Song, Joo Y., Woroniecka, Renata, Rymkiewicz, Grzegorz, Klapper, Wolfram, Hartmann, Elena M., Sujobert, Pierre, Wlodarska, Iwona, Ferry, Judith A., Gaulard, Philippe, Ott, German, Rosenwald, Andreas, Lopez-Guillermo, Armando, Quintanilla-Martinez, Leticia, Harris, Nancy L., Jaffe, Elaine S., Siebert, Reiner, Campo, Elias, Beà, Sílvia

“…Cyclin D1− mantle cell lymphomas (MCLs) are not well characterized, in part because of the difficulties in their recognition. SOX11 has been identified…”
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The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii by Aghabi, Dana, Sloan, Megan, Gill, Grace, Hartmann, Elena, Antipova, Olga, Dou, Zhicheng, Guerra, Alfredo J., Carruthers, Vern B., Harding, Clare R.

“…Iron is essential to cells as a cofactor in enzymes of respiration and replication, however without correct storage, iron leads to the formation of dangerous…”
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CCL3 chemokine expression by chronic lymphocytic leukemia cells orchestrates the composition of the microenvironment in lymph node infiltrates by Hartmann, Elena M, Rudelius, Martina, Burger, Jan A, Rosenwald, Andreas

“…Previous experiments demonstrated that survival and proliferation of chronic lymphocytic leukemia (CLL) cells depends upon complex cross-talk between CLL cells…”
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The complex landscape of genetic alterations in mantle cell lymphoma by Royo, Cristina, Salaverria, Itziar, Hartmann, Elena M, Rosenwald, Andreas, Campo, Elías, Beà, Sílvia

“…Abstract Mantle cell lymphoma (MCL) is genetically characterized by the t(11;14)(q13;q32) which deregulates cyclin D1. Small subsets of cases have been…”
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Natalizumab exerts direct signaling capacity and supports a pro-inflammatory phenotype in some patients with multiple sclerosis by Benkert, Thomas F, Dietz, Lena, Hartmann, Elena M, Leich, Ellen, Rosenwald, Andreas, Serfling, Edgar, Buttmann, Mathias, Berberich-Siebelt, Friederike

“…Natalizumab is a recombinant monoclonal antibody raised against integrin alpha-4 (CD49d). It is approved for the treatment of patients with multiple sclerosis…”
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In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma by Philipp‐Abbrederis, Kathrin, Herrmann, Ken, Knop, Stefan, Schottelius, Margret, Eiber, Matthias, Lückerath, Katharina, Pietschmann, Elke, Habringer, Stefan, Gerngroß, Carlos, Franke, Katharina, Rudelius, Martina, Schirbel, Andreas, Lapa, Constantin, Schwamborn, Kristina, Steidle, Sabine, Hartmann, Elena, Rosenwald, Andreas, Kropf, Saskia, Beer, Ambros J, Peschel, Christian, Einsele, Hermann, Buck, Andreas K, Schwaiger, Markus, Götze, Katharina, Wester, Hans‐Jürgen, Keller, Ulrich

“…CXCR4 is a G‐protein‐coupled receptor that mediates recruitment of blood cells toward its ligand SDF‐1. In cancer, high CXCR4 expression is frequently…”
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Genomic and Gene Expression Profiling Defines Indolent Forms of Mantle Cell Lymphoma by FERNANDEZ, Verònica, SALAMERO, Olga, HERNANDEZ, Luis, AGOSTINELLI, Claudio, SARGENT, Rachel L, ROZMAN, Maria, AYMERICH, Marta, COLOMER, Dolors, VILLAMOR, Neus, SWERDLOW, Steven H, PILERI, Stefano A, BOSCH, Francesc, ESPINET, Blanca, PIRIS, Miguel A, MONTSERRAT, Emili, OTT, German, ROSENWALD, Andreas, LOPEZ-GUILLERMO, Armando, JARES, Pedro, SERRANO, Sergi, CAMPO, Elias, SOLE, Francesc, ROYO, Cristina, NAVARRO, Alba, CAMACHO, Francisca, BEA, Silvia, HARTMANN, Elena, AMADOR, Virginia

“…Mantle cell lymphoma (MCL) is typically a very aggressive disease with poor outcomes, but some cases display an indolent behavior that might not necessitate…”
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Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling by Beà, Sílvia, Salaverria, Itziar, Armengol, Lluís, Pinyol, Magda, Fernández, Verónica, Hartmann, Elena M., Jares, Pedro, Amador, Virginia, Hernández, Luís, Navarro, Alba, Ott, German, Rosenwald, Andreas, Estivill, Xavier, Campo, Elias

“…Mantle cell lymphoma (MCL) is genetically characterized by the t(11;14)(q13;q32) translocation and a high number of secondary chromosomal alterations. However,…”
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A case of nodular lymphocyte predominant Hodgkin lymphoma with unexpected EBV-latency type by Rosenfeldt, Mathias T., Hartmann, Elena M., Leng, Corinna, Rosenwald, Andreas, Anagnostopoulos, Ioannis

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Genetic variations in human ATP2B4 gene alter Plasmodium falciparum in vitro growth in RBCs from Gambian adults by Joof, Fatou, Hartmann, Elena, Jarvis, Alison, Colley, Alhassan, Cross, James H, Avril, Marion, Prentice, Andrew M, Cerami, Carla

“…Polymorphisms in ATP2B4 coding for PMCA4b, the primary regulator of erythrocyte calcium concentration, have been shown by GWAS and cross-sectional studies to…”
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Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling by Hartmann, Elena M., Campo, Elias, Wright, George, Lenz, Georg, Salaverria, Itziar, Jares, Pedro, Xiao, Wenming, Braziel, Rita M., Rimsza, Lisa M., Chan, Wing-Chung, Weisenburger, Dennis D., Delabie, Jan, Jaffe, Elaine S., Gascoyne, Randy D., Dave, Sandeep S., Mueller-Hermelink, Hans-Konrad, Staudt, Louis M., Ott, German, Beà, Sílvia, Rosenwald, Andreas

“…The genome of mantle cell lymphoma (MCL) is, in addition to the translocation t(11;14), characterized by a high number of secondary chromosomal gains and…”
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Correction: Genetic variations in human ATP2B4 gene alter Plasmodium falciparum in vitro growth in RBCs from Gambian adults by Joof, Fatou, Hartmann, Elena, Jarvis, Alison, Colley, Alhassan, Cross, James H, Avril, Marion, Prentice, Andrew M, Cerami, Carla

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Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations by Leich, Ellen, Salaverria, Itziar, Bea, Silvia, Zettl, Andreas, Wright, George, Moreno, Victor, Gascoyne, Randy D., Chan, Wing-Chung, Braziel, Rita M., Rimsza, Lisa M., Weisenburger, Dennis D., Delabie, Jan, Jaffe, Elaine S., Lister, Andrew, Fitzgibbon, Jude, Staudt, Louis M., Hartmann, Elena M., Mueller-Hermelink, Hans-Konrad, Campo, Elias, Ott, German, Rosenwald, Andreas

“…Follicular lymphoma (FL) is genetically characterized by the presence of the t(14;18)(q32;q21) chromosomal translocation in approximately 90% of cases. In…”
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SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype by MOZOS, Ana, ROYO, Cristina, JAFFE, Elaine S, RUIZ-MARCELLAN, Carmen, DAVE, Sandeep, RIMSZA, Lisa, BRAZIEL, Rita, GASCOYNE, Randy D, SOLE, Francisco, LOPEZ-GUILLERMO, Armando, COLOMER, Dolors, STAUDT, Louis M, HARTMANN, Elena, ROSENWALD, Andreas, OTT, German, JARES, Pedro, CAMPO, Elias, DE JONG, Daphne, BARO, Cristina, VALERA, Alexandra, KAI FU, WEISENBURGER, Dennis D, DELABIE, Jan, CHUANG, Shih-Sung

“…Cyclin D1-negative mantle cell lymphoma is difficult to distinguish from other small B-cell lymphomas. The clinical and pathological characteristics of…”
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Heterogeneous histomorphology, yet homogeneous vascular smooth muscle cell dedifferentiation, characterize human aneurysm disease by Busch, Albert, MD, Hartmann, Elena, MD, Grimm, Caroline, Ergün, Süleyman, MD, Kickuth, Ralph, MD, Otto, Christoph, PhD, Kellersmann, Richard, MD, Lorenz, Udo, MD

“…Abstract Objective Abdominal aortic aneurysm (AAA) is a frequent, potentially life-threatening, disease that can only be treated by surgical means such as open…”
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CCL3 (MIP-1α) plasma levels and the risk for disease progression in chronic lymphocytic leukemia by Sivina, Mariela, Hartmann, Elena, Kipps, Thomas J., Rassenti, Laura, Krupnik, Diana, Lerner, Susan, LaPushin, Ruth, Xiao, Lianchun, Huang, Xuelin, Werner, Lillian, Neuberg, Donna, Kantarjian, Hagop, O'Brien, Susan, Wierda, William G., Keating, Michael J., Rosenwald, Andreas, Burger, Jan A.

“…B-cell receptor (BCR) signaling has been inferred as an important mechanism for disease progression in chronic lymphocytic leukemia (CLL) and other B-cell…”
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