Search Results - "Hartmane, Dace"

Increased Trimethylamine N-Oxide Is Not Associated with Oxidative Stress Markers in Healthy Aged Women by Lysiak-Szydlowska, Wieslawa, Grinberga, Solveiga, Hartmane, Dace, Sawicka, Angelika Katarzyna, Samulak, Joanna Jolanta, Olek, Robert Antoni, Pugovics, Osvalds

“…Increased plasma trimethylamine N-oxide (TMAO) levels have been associated with cardiovascular diseases (CVD). L-carnitine induces TMAO elevation in human…”
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l-Carnitine Supplementation in Older Women. A Pilot Study on Aging Skeletal Muscle Mass and Function by Sawicka, Angelika K, Hartmane, Dace, Lipinska, Patrycja, Wojtowicz, Ewa, Lysiak-Szydlowska, Wieslawa, Olek, Robert A

“…Skeletal muscle wasting, associated with aging, may be regulated by the inflammatory cytokines as well as by insulin-like growth factor 1 (IGF-1). l-carnitine…”
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CntA oxygenase substrate profile comparison and oxygen dependency of TMA production in Providencia rettgeri by Kalnins, Gints, Sevostjanovs, Eduards, Hartmane, Dace, Grinberga, Solveiga, Tars, Kaspars

“…CntA oxygenase is a Rieske 2S‐2Fe cluster‐containing protein that has been previously described as able to produce trimethylamine (TMA) from carnitine,…”
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L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women by Samulak, Joanna J, Sawicka, Angelika K, Hartmane, Dace, Grinberga, Solveiga, Pugovics, Osvalds, Lysiak-Szydlowska, Wieslawa, Olek, Robert A

“…L-carnitine can be metabolized to trimethylamine N-oxide (TMAO), a molecule that promotes atherogenesis through its interaction with macrophages and lipid…”
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Determination of trimethylamine-N-oxide in combination with l-carnitine and γ-butyrobetaine in human plasma by UPLC/MS/MS by Grinberga, Solveiga, Dambrova, Maija, Latkovskis, Gustavs, Strele, Ieva, Konrade, Ilze, Hartmane, Dace, Sevostjanovs, Eduards, Liepinsh, Edgars, Pugovics, Osvalds

“…An ultra‐high‐performance liquid chromatography–mass spectrometry (UPLC/MS/MS) method was developed and validated for the quantification of…”
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Carnitine and γ‐Butyrobetaine Stimulate Elimination of Meldonium due to Competition for OCTN2‐mediated Transport by Liepinsh, Edgars, Makarova, Elina, Sevostjanovs, Eduards, Hartmane, Dace, Cirule, Helena, Zharkova‐Malkova, Olga, Grinberga, Solveiga, Dambrova, Maija

“…Meldonium (3‐(2,2,2‐trimethylhydrazinium)propionate) is the most potent clinically used inhibitor of organic cation transporter 2 (OCTN2). Inhibition of OCTN2…”
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Carnitine and [gamma]-Butyrobetaine Stimulate Elimination of Meldonium due to Competition for OCTN2-mediated Transport by Liepinsh, Edgars, Makarova, Elina, Sevostjanovs, Eduards, Hartmane, Dace, Cirule, Helena, Zharkova-Malkova, Olga, Grinberga, Solveiga, Dambrova, Maija

“…Meldonium (3-(2,2,2-trimethylhydrazinium)propionate) is the most potent clinically used inhibitor of organic cation transporter 2 (OCTN2). Inhibition of OCTN2…”
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Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients by Zaharenko, Linda, Kalnina, Ineta, Geldnere, Kristine, Konrade, Ilze, Grinberga, Solveiga, Židzik, Jozef, Javorský, Martin, Lejnieks, Aivars, Nikitina-Zake, Liene, Fridmanis, Davids, Peculis, Raitis, Radovica-Spalvina, Ilze, Hartmane, Dace, Pugovics, Osvalds, Tkáč, Ivan, Klimčáková, Lucia, Pīrāgs, Valdis, Klovins, Janis

“…Objective(s) High variability in clinical response to metformin is often observed in type 2 diabetes (T2D) patients, and it highlights the need for…”
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