Search Results - "Hartman, Rosemarie F."

Cell Cycle Arrest and Apoptosis Induction by an Anticancer Chalcone Epoxide by Han, Haiyong, Zhao, Yu, Cuthbertson, Timothy, Hartman, Rosemarie F., Rose, Seth D.

“…Safe and effective chemotherapeutic agents for the treatment of pancreatic cancer remain elusive. We found that chalcone epoxides…”
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Kinetics and Mechanism of the Addition of Nucleophiles to α,β-Unsaturated Thiol Esters by Hartman, Rosemarie F, Rose, Seth D

“…Compounds containing the UV-absorbing chromophores p-methoxycinnamate, p-methoxycinnamide, or anthranilate and an α,β- or α,β,γ,δ-unsaturated thiol ester…”
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Emollient, humectant, and fluorescent α,β-unsaturated thiol esters for long-acting skin applications by Robinson, Carmen, Hartman, Rosemarie F., Rose, Seth D.

“…α,β-Unsaturated thiol esters are subject to Michael-type addition by nucleophiles such as thiolates. Suitably substituted compounds may have utility as…”
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A possible chain reaction in photosensitized splitting of pyrimidine dimers by a protonated, oxidized flavin by Hartman, Rosemarie F, Rose, Seth D

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CIDNP Evidence for Reversibility of the Photosensitized Splitting of Pyrimidine Dimers by Pouwels, Petra J. W, Hartman, Rosemarie F, Rose, Seth D, Kaptein, Robert

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Energy and electron transfer processes in flavoprotein-mediated DNA repair by Heelis, Paul F., Hartman, Rosemarie F., Rose, Seth D.

“…The flavin photoenzyme, DNA photolyasesm utilizes a pMhotom to repair the main damage to DNA (pyrimidine dimers) caused by UV light. DNA photolyases are…”
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Efficient photosensitized pyrimidine dimer splitting by a reduced flavin requires the deprotonated flavin by Hartman, Rosemarie F, Rose, Seth D

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Inactivation of Protein Farnesyltransferase by Active-Site-Targeted Dicarbonyl Compounds by Okolotowicz, Karl J., Lee, Wei-Jen, Hartman, Rosemarie F., Kim, Ann Y., Ottersberg, Steven R., Robinson, Jr, Dale E., Lefler, Scott R., Rose, Seth D.

“…Upon farnesylation by protein farnesyltransferase (FTase), key proteins become compartmentalized in cells. For example, cell membrane localization is essential…”
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Electron delocalization in pyrimidine dimers and the implications for enzyme-catalyzed dimer cycloreversion by Hartman, Rosemarie F, Van Camp, John R, Rose, Seth D

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Photosensitization of pyrimidine dimer splitting by a covalently bound indole by Van Camp, J R, Young, T, Hartman, R F, Rose, S D

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Transient intermediates in intramolecularly photosensitized pyrimidine dimer splitting by indole derivatives by Young, T, Kim, S T, Van Camp, J R, Hartman, R F, Rose, S D

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Kinetics of the addition of osmium oxide (OsO4) to furans: mono(osmate ester) vs. bis(osmate ester) formation by Hartman, Rosemarie F, Rose, Seth D

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Photo-CIDNP study of pyrimidine dimer splitting. II: Reactions involving pyrimidine radical anion intermediates by Pouwels, P J, Hartman, R F, Rose, S D, Kaptein, R

“…A series of photo-CIDNP (chemically induced dynamic nuclear polarization) experiments were performed on pyrimidine monomers and dimers, using the…”
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Photo-CIDNP study of pyrimidine dimer splitting. I: Reactions involving pyrimidine radical cation intermediates by Pouwels, P J, Hartman, R F, Rose, S D, Kaptein, R

“…The light-induced splitting of pyrimidine dimers was studied using the electron acceptor anthraquinone-2-sulfonate (AQS) as a photosensitizer. To this end,…”
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Solvent dependence of pyrimidine dimer splitting in a covalently linked dimer-indole system by Kim, S T, Hartman, R F, Rose, S D

“…Cyclobutadipyrimidines (pyrimidine dimers) undergo splitting that is photosensitized by indole derivatives. We have prepared a compound in which a two-carbon…”
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Detection of the excited singlet state of a deprotonated, reduced flavin by Heelis, P F, Hartman, R F, Rose, S D

“…The excited singlet state of a deprotonated, reduced flavin [1,5-dihydro-N(3)-carboxymethyllumiflavin] in aqueous solution at pH 8 has been detected by laser…”
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Detection of radical ion intermediates in flavin-photosensitized pyrimidine dimer splitting by Heelis, P F, Hartman, R F, Rose, S D

“…Photosensitized splitting of cis-syn- and trans-syn-1,3-dimethyluracil dimers by 2',3',4',5'-tetraacetylriboflavin in acetonitrile containing a trace of…”
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Detection of a reduced-flavin triplet state in free flavins and DNA photolyase by Heelis, P F, Rowley-Williams, C A, Hartman, R F, Rose, S D

“…A transient species was observed upon laser excitation (lambda exc = 355 nm) of reduced flavins (cFIH2) under anaerobic conditions. The transient decayed with…”
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Methacrylate polymerization by AzoRNA: potential usefulness for chromosomal localization of genes by Hartman, R F, Brown, G L, Rose, S D

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Enzymatic addition of modified cytosine nucleotides to DNA. Methacrylate polymerization by an azo pyrimidine by Brown, G L, Hartman, R F, Rose, S D

“…An azo pyrimidine that induces the polymerization of 1-glyceryl methacrylate has been prepared. 1-Glyceryl methacrylate contains substituent glycol groups for…”
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