Search Results - "Hartman, Katrina M."
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Strategies used for the COVID-OUT decentralized trial of outpatient treatment of SARS-CoV-2
Published in Journal of clinical and translational science (2023)“…The COVID-19 pandemic accelerated the development of decentralized clinical trials (DCT). DCT's are an important and pragmatic method for assessing health…”
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Journal Article -
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Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccination and Booster on Coronavirus Disease 2019 (COVID-19) Symptom Severity Over Time in the COVID-OUT Trial
Published in Clinical infectious diseases (08-02-2023)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination has decreasing protection from acquiring any infection with emergence of new variants;…”
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Journal Article -
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Vaccination Against SARS-CoV-2 Is Associated With a Lower Viral Load and Likelihood of Systemic Symptoms
Published in Open forum infectious diseases (01-05-2022)“…Abstract Background Data conflict on whether vaccination decreases severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load. The objective of…”
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Journal Article -
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A Comparison of Recruitment Methods for a Remote, Nationwide Clinical Trial for COVID-19 Treatment
Published in Open forum infectious diseases (01-07-2024)“…Abstract This study describes decentralized recruitment and enrollment for a COVID-19 treatment trial, while comparing 5 primary recruitment methods: search…”
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Journal Article -
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Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial
Published in The Lancet infectious diseases (01-10-2023)“…Post-COVID-19 condition (also known as long COVID) is an emerging chronic illness potentially affecting millions of people. We aimed to evaluate whether…”
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Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19
Published in The New England journal of medicine (18-08-2022)“…In this trial involving overweight or obese outpatients with Covid-19, investigators found that none of three repurposed drugs (metformin, ivermectin, and…”
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Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19
Published in Clinical infectious diseases (16-08-2024)“…Metformin has antiviral activity against RNA viruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mechanism appears to be…”
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Journal Article -
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Impact of SARS-CoV-2 vaccination and booster on COVID-19 symptom severity over time in the COVID-OUT trial
Published in Clinical infectious diseases (17-09-2022)“…Vaccination against SARS-CoV-2 was associated with reduced Covid-19 symptom severity in a sample of low to moderate risk adults who were enrolled in an…”
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Inhibition of bovine brain glutathione transferase by DNA
Published 01-01-1993“…Glutathione transferase is a multifunctional enzyme known most commonly as a detoxifier. It was separated from the cystol of bovine brain. It was also…”
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Dissertation