Search Results - "Hartley, Maryalice"

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  1. 1
    1751-P: SERCA2 Regulates ER Lipid Composition and Proinsulin Processing

    1751-P: SERCA2 Regulates ER Lipid Composition and Proinsulin Processing by HARTLEY, MARYALICE, PEARSON, MACKENZIE J., SYED, FAROOQ, BUI, HAI, KONO, TATSUYOSHI, ROTH, KENNETH D., EVANS-MOLINA, CARMELLA

    Published in Diabetes (New York, N.Y.) (20-06-2023)
    “…Endoplasmic reticulum calcium (ER Ca2+) levels are primarily maintained through the sarco-ER Ca2+ ATPase (SERCA) pump. We have demonstrated reduced SERCA2…”
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  2. 2
    Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet-Induced Obese Rats

    Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet-Induced Obese Rats by Estridge, Thomas B, Dey, Asim B, Reidy, Charles, Yu, Xiaohong, Zhang, Yuke, Hartley, Maryalice, Milligan, Paul L, Jin, Najia, Kowala, Mark C, Leohr, Jennifer K, Fretland, Adrian J, Mabry, Thomas E, Luffer-Atlas, Debra, Luo, M Jane

    “…LY2584702 is an inhibitor of p70 S6 kinase-1 previously developed for the treatment of cancer. In two phase 1 trials in oncology patients, significant…”
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