Search Results - "Hartl, A"

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity by Schmid, Daniela, Park, Chun Gwon, Hartl, Christina A., Subedi, Nikita, Cartwright, Adam N., Puerto, Regina Bou, Zheng, Yiran, Maiarana, James, Freeman, Gordon J., Wucherpfennig, Kai W., Irvine, Darrell J., Goldberg, Michael S.

“…Targeted delivery of compounds to particular cell subsets can enhance therapeutic index by concentrating their action on the cells of interest. Because…”
Get full text

Stable Chromosome Condensation Revealed by Chromosome Conformation Capture by Eagen, Kyle P., Hartl, Tom A., Kornberg, Roger D.

“…Chemical cross-linking and DNA sequencing have revealed regions of intra-chromosomal interaction, referred to as topologically associating domains (TADs),…”
Get full text

Condensin II promotes the formation of chromosome territories by inducing axial compaction of polyploid interphase chromosomes by Bauer, Christopher R, Hartl, Tom A, Bosco, Giovanni

“…The eukaryotic nucleus is both spatially and functionally partitioned. This organization contributes to the maintenance, expression, and transmission of…”
Get full text

A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis by Wagenblast, Elvin, Soto, Mar, Gutiérrez-Ángel, Sara, Hartl, Christina A., Gable, Annika L., Maceli, Ashley R., Erard, Nicolas, Williams, Alissa M., Kim, Sun Y., Dickopf, Steffen, Harrell, J. Chuck, Smith, Andrew D., Perou, Charles M., Wilkinson, John E., Hannon, Gregory J., Knott, Simon R. V.

“…Different clones of a mammary tumour cell line possess differential abilities to contribute to the formation of metastasis; the expression of Serpine2 and Slp1…”
Get full text

A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation by Swamy, Mahima, Beck-Garcia, Katharina, Beck-Garcia, Esmeralda, Hartl, Frederike A., Morath, Anna, Yousefi, O. Sascha, Dopfer, Elaine Pashupati, Molnár, Eszter, Schulze, Anna K., Blanco, Raquel, Borroto, Aldo, Martín-Blanco, Nadia, Alarcon, Balbino, Höfer, Thomas, Minguet, Susana, Schamel, Wolfgang W.A.

“…Signaling through the T cell receptor (TCR) controls adaptive immune responses. Antigen binding to TCRαβ transmits signals through the plasma membrane to…”
Get full text

Randomised clinical trial: the effects of a multispecies probiotic vs. placebo on innate immune function, bacterial translocation and gut permeability in patients with cirrhosis by Horvath, A., Leber, B., Schmerboeck, B., Tawdrous, M., Zettel, G., Hartl, A., Madl, T., Stryeck, S., Fuchs, D., Lemesch, S., Douschan, P., Krones, E., Spindelboeck, W., Durchschein, F., Rainer, F., Zollner, G., Stauber, R. E., Fickert, P., Stiegler, P., Stadlbauer, V.

“…Summary Background Probiotics may correct intestinal dysbiosis and proinflammatory conditions in patients with liver cirrhosis. Aim To test the effects of a…”
Get full text

Chromosome Alignment and Transvection Are Antagonized by Condensin II by Hartl, Tom A, Smith, Helen F, Bosco, Giovanni

“…Polytene chromosome structure is a characteristic of some polyploid cells where several to thousands of chromatids are closely associated with perfect…”
Get full text

Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma by Purzner, Teresa, Purzner, James, Buckstaff, Taylor, Cozza, Giorgio, Gholamin, Sharareh, Rusert, Jessica M, Hartl, Tom A, Sanders, John, Conley, Nicholas, Ge, Xuecai, Langan, Marc, Ramaswamy, Vijay, Ellis, Lauren, Litzenburger, Ulrike, Bolin, Sara, Theruvath, Johanna, Nitta, Ryan, Qi, Lin, Li, Xiao-Nan, Li, Gordon, Taylor, Michael D, Wechsler-Reya, Robert J, Pinna, Lorenzo A, Cho, Yoon-Jae, Fuller, Margaret T, Elias, Joshua E, Scott, Matthew P

“…A major limitation of targeted cancer therapy is the rapid emergence of drug resistance, which often arises through mutations at or downstream of the drug…”
Get more information

Phospho-mimetic CD3ε variants prevent TCR and CAR signaling by Woessner, Nadine M, Brandl, Simon M, Hartmann, Sara, Schamel, Wolfgang W, Hartl, Frederike A, Minguet, Susana

“…Antigen binding to the T cell antigen receptor (TCR) leads to the phosphorylation of the immunoreceptor tyrosine-based activation motifs (ITAMs) of the CD3…”
Get full text

Development of a custom OMI NO2 data product for evaluating biases in a regional chemistry transport model by Kuhlmann, G, Lam, Y F, Cheung, H M, Hartl, A, Fung, J C H, Chan, P W, Wenig, M O

“…In this paper, we present the custom Hong Kong NO2 retrieval (HKOMI) for the Ozone Monitoring Instrument (OMI) on board the Aura satellite which was used to…”
Get full text

Proton conductivity in a hureaulite-type compound, Mn5[(PO4)2(PO3(OH))2](HOH)4 by Hartl, A., Park, S.-H., Hoelzel, M., Paul, N., Gilles, R.

“…The manganese endmember of hureaulite (Mn-hureaulite, Mn2+5(PO4)2(PO3(OH))2(HOH)4 with a minor trace of Sr2+) was synthesized under various hydrothermal…”
Get full text

Characterization of ions at Alpine waterfalls by Kolarž, P, Gaisberger, M, Madl, P, Hofmann, W, Ritter, M, Hartl, A

“…During a three-year field campaign of measuring waterfall generated ions, we monitored five different waterfalls in the Austrian Alps. Most measurements were…”
Get full text

Observations of tropospheric NO2 using ground based MAX-DOAS and OMI measurements during the Shanghai World Expo 2010 by Chan, K.L., Hartl, A., Lam, Y.F., Xie, P.H., Liu, W.Q., Cheung, H.M., Lampel, J., Pöhler, D., Li, A., Xu, J., Zhou, H.J., Ning, Z., Wenig, M.O.

“…During the Shanghai World Expo 2010 ground based Multi-Axis Differential Optical Absorption Spectroscopy (MAX-DOAS) measurements of tropospheric nitrogen…”
Get full text

Characterizing low fluence thresholds for in vitro photodynamic therapy by Hartl, Brad A, Hirschberg, Henry, Marcu, Laura, Cherry, Simon R

“…The translation of photodynamic therapy (PDT) to the clinic has mostly been limited to superficial diseases where traditional light delivery is noninvasive. To…”
Get full text

Orientation-dependent compression/tension asymmetry of short glass fiber reinforced polypropylene: Deformation, damage and failure by Hartl, A.M., Jerabek, M., Freudenthaler, P., Lang, R.W.

“…Short glass fiber reinforced polypropylene (sgf-PP) is increasingly employed in structural components which are subjected to a variety of loading conditions…”
Get full text

Fluorescence Lifetime Spectroscopy and Imaging in Neurosurgery by Marcu, L., Hartl, B. A.

“…Clinical outcome of patients diagnosed with primary brain tumor has been correlated with the extent of surgical resection. In treating this disease, the…”
Get full text

Anti-CD3 Fab Fragments Enhance Tumor Killing by Human γδ T Cells Independent of Nck Recruitment to the γδ T Cell Antigen Receptor by Juraske, Claudia, Wipa, Piyamaporn, Morath, Anna, Hidalgo, Jose Villacorta, Hartl, Frederike A, Raute, Katrin, Oberg, Hans-Heinrich, Wesch, Daniela, Fisch, Paul, Minguet, Susana, Pongcharoen, Sutatip, Schamel, Wolfgang W

“…T lymphocytes expressing the γδ T cell receptor (γδ TCR) can recognize antigens expressed by tumor cells and subsequently kill these cells. γδ T cells are…”
Get full text

Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosis by Hartl, Tom A, Sweeney, Sarah J, Knepler, Peter J, Bosco, Giovanni

“…Several meiotic processes ensure faithful chromosome segregation to create haploid gametes. Errors to any one of these processes can lead to zygotic aneuploidy…”
Get full text

Regularisation model study for the least-squares retrieval of aerosol extinction time series from UV/VIS MAX-DOAS observations for a ground layer profile parameterisation by Hartl, A, Wenig, M. O

“…The retrieval of tropospheric aerosol extinctions from MAX-DOAS observations of O4 using a small number of three or four extinction profile parameters suitable…”
Get full text

Galactokinase 1 is the source of elevated galactose‐1‐phosphate and cerebrosides are modestly reduced in a mouse model of classic galactosemia by Mangini, Linley, Lawrence, Roger, Lopez, Manuel E., Graham, Timothy C., Bauer, Christopher R., Nguyen, Hang, Su, Cheng, Ramphal, John, Crawford, Brett E., Hartl, Tom A.

“…Classic galactosemia (CG) arises from loss‐of‐function mutations in the Galt gene, which codes for the enzyme galactose‐1‐phosphate uridylyltransferase (GALT),…”
Get full text