Search Results - "Hart, Shane M."

High-Throughput Method for the Production and Analysis of Large Natural Product Libraries for Drug Discovery by Eldridge, Gary R, Vervoort, Hélène C, Lee, Chris M, Cremin, Peadar A, Williams, Caroline T, Hart, Shane M, Goering, Matt G, O'Neil-Johnso, Mark, Zeng, Lu

“…High-throughput methods were applied to the production, analysis, and characterization of libraries of natural products in order to accelerate the drug…”
Get full text

Discovery of 6,7-Dihydro‑5H‑pyrrolo[2,3‑a]pyrimidines as Orally Available G Protein-Coupled Receptor 119 Agonists by Katamreddy, Subba R, Carpenter, Andrew J, Ammala, Carina E, Boros, Eric E, Brashear, Ron L, Briscoe, Celia P, Bullard, Sarah R, Caldwell, Richard D, Conlee, Christopher R, Croom, Dallas K, Hart, Shane M, Heyer, Dennis O, Johnson, Paul R, Kashatus, Jennifer A, Minick, Doug J, Peckham, Gregory E, Ross, Sean A, Roller, Shane G, Samano, Vicente A, Sauls, Howard R, Tadepalli, Sarva M, Thompson, James B, Xu, Yun, Way, James M

“…GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines…”
Get full text

Miniaturization of the structure elucidation of novel natural products--two trace antibacterial acylated caprylic alcohol glycosides from Arctostaphylos pumila by Hu, Jin-Feng, Yoo, Hye-Dong, Williams, Caroline T, Garo, Eliane, Cremin, Peadar A, Zeng, Lu, Vervoort, Helene C, Lee, Chris M, Hart, Shane M, Goering, Matt G, O'Neil-Johnson, Mark, Eldridge, Gary R

“…High-throughput isolation, purification and analysis methods applied to natural products libraries from plants gave rise to the discovery of two novel acylated…”
Get more information

Discovery of 6,7-Dihydro-5 H -pyrrolo[2,3- a ]pyrimidines as Orally Available G Protein-Coupled Receptor 119 Agonists by Katamreddy, Subba R., Carpenter, Andrew J., Ammala, Carina E., Boros, Eric E., Brashear, Ron L., Briscoe, Celia P., Bullard, Sarah R., Caldwell, Richard D., Conlee, Christopher R., Croom, Dallas K., Hart, Shane M., Heyer, Dennis O., Johnson, Paul R., Kashatus, Jennifer A., Minick, Doug J., Peckham, Gregory E., Ross, Sean A., Roller, Shane G., Samano, Vicente A., Sauls, Howard R., Tadepalli, Sarva M., Thompson, James B., Xu, Yun, Way, James M.

Get full text