Search Results - "Hart, Andrew P."
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PD-1 and CTLA-4 exert additive control of effector regulatory T cells at homeostasis
Published in Frontiers in immunology (07-03-2023)“…At homeostasis, a substantial proportion of Foxp3 T regulatory cells (T ) have an activated phenotype associated with enhanced TCR signals and these effector T…”
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A review of signaling and transcriptional control in T follicular helper cell differentiation
Published in Journal of leukocyte biology (01-01-2022)“…T follicular helper (Tfh) cells are a critical component of adaptive immunity and assist in optimal Ab‐mediated defense. Multiple effector functions of Tfh…”
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PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection
Published in Nature immunology (01-05-2022)“…Phenotypic and transcriptional profiling of regulatory T (T reg ) cells at homeostasis reveals that T cell receptor activation promotes T reg cells with an…”
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Helios+ and RORγt+ Treg populations are differentially regulated by MHCII, CD28, and ICOS to shape the intestinal Treg pool
Published in Mucosal immunology (01-06-2023)“…The balance between RORγt+and Helios+Tregs in the small intestine is modulated by their differential costimulatory requirements. Our data show that intestinal…”
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Analysis of the mechanisms that maintain intestinal regulatory T cells
Published in The Journal of immunology (1950) (01-05-2022)“…Regulatory T cells (Tregs) play an important role maintaining intestinal homeostasis. The Treg pool from the small intestine lamina propria (siLP) include two…”
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Dissecting the tissue-specific mechanisms that support the maintenance of intestinal regulatory T cells
Published in The Journal of immunology (1950) (01-05-2019)“…Intestinal regulatory T cells (Tregs) are important to maintain tolerance toward food antigens (Ag) and commensals. Understanding the mechanisms for…”
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The effect of nitroglycerin on response to tracheal intubation: assessment by radionuclide angiography
Published in Anesthesia and analgesia (01-06-1989)“…The effect of intravenous (IV) nitroglycerin (NTG) on perioperative myocardial ischemia as detected by single pass radionuclide angiocardiography was studied…”
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