Search Results - "Harsh, Donna M."

Endotracheal Intubation in Patients Treated for Prehospital Status Epilepticus by Vohra, Taher T., Miller, Joseph B., Nicholas, Katherine S., Varelas, Panayiotis N., Harsh, Donna M., Durkalski, Valerie, Silbergleit, Robert, Wang, Henry E.

“…Introduction Limited data describe the frequency, timing, or indications for endotracheal intubation (ETI) in patients with status epilepticus. A better…”
Get full text

Clustering of Urokinase Receptors (uPAR; CD87) Induces Proinflammatory Signaling in Human Polymorphonuclear Neutrophils by Sitrin, Robert G, Pan, Pauline M, Harper, Hollie A, Todd, Robert F., III, Harsh, Donna M, Blackwood, R. Alexander

“…Leukocytes use urokinase receptors (uPAR; CD87) in adhesion, migration, and proteolysis of matrix proteins. Typically, uPAR clusters at cell-substratum…”
Get full text

Identification of glyceraldehyde-3-phosphate dehydrogenase as a Ca2+-dependent fusogen in human neutrophil cytosol by Hessler, Ronald J., Blackwood, R. Alexander, Brock, Thomas G., Francis, Joseph W., Harsh, Donna M., Smolen, James E.

“…The membrane fusion events observed during neutrophil degranulation are important aspects of the immunoregulatory system. In an attempt to understand the…”
Get full text

Lipid Raft Compartmentalization of Urokinase Receptor Signaling in Human Neutrophils by Sitrin, Robert G, Johnson, Douglas R, Pan, Pauline M, Harsh, Donna M, Huang, Jibiao, Petty, Howard R, Blackwood, R. Alexander

“…Urokinase plasminogen activator (uPA) receptors (uPAR) can be engaged for activation signaling either by aggregation or by binding exogenous uPA. These…”
Get full text

PLA2 promotes fusion between PMN-specific granules and complex liposomes by Blackwood, R. Alexander, Transue, Amy T., Harsh, Donna M., Brower, Ruth C., Zacharek, Sima J., Smolen, James E., Hessler, Ronald J.

“…Neutrophil stimulation results in the activation of a variety of phospholipases, including phospholipase A2 (PLA2), which releases arachidonic acid from the 2…”
Get full text

Phospholipase A2-Mediated Fusion of Neutrophil-Derived Membranes Is Augmented by Phosphatidic Acid by Harsh, Donna M., Blackwood, R.Alexander

“…Phosphatidic acid (PA), the product of phospholipase D (PLD) metabolism, is not only an important second messenger in neutrophil signal transduction but PA…”
Get full text

PLD AUGMENTS CALCIUM INDUCED DEGRANULATION IN STREPTOLYSIN O PERMEABILIZED NEUTROPHILS. • 901 by Blackwood, R Alexander, Zacharek, Sima J, Song, Eunice, Harsh, Donna M

Get full text

Development of an aqueous-space mixing assay for fusion of granules and plasma membranes from human neutrophils by Blackwood, R A, Smolen, J E, Hessler, R J, Harsh, D M, Transue, A

“…Several models have been developed to study neutrophil degranulation. At the most basic level, phospholipid vesicles have been used to investigate the lipid…”
Get full text