Search Results - "Harsfalvi, Jolàn"
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1
Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibα reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibα
Published in Blood (01-08-2001)“…The interaction of von Willebrand factor (vWF) with the platelet receptor glycoprotein Ibα (GPIbα) is important for platelet adhesion at high shear stress. Two…”
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2
Acute phase proteins in the diagnosis and prediction of cirrhosis associated bacterial infections
Published in Liver international (01-04-2012)“…Background Bacterial infections are common cause of morbidity and mortality in patients with cirrhosis. The early diagnosis of these infections is rather…”
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3
Follow-up of thrombin generation after prostate cancer surgery: global test for increased hypercoagulability
Published in PloS one (07-12-2012)“…Recent studies provided evidence that evaluation of thrombin generation identifies patients at thrombotic risk. Thrombin generation has a central role in…”
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4
Factor XIII, clot structure, thrombosis
Published in Thrombosis research (01-03-2012)“…Abstract Blood coagulation factor XIII (FXIII) is a tetrameric protein consisting of two catalytic A (FXIII-A) and two carrier/inhibitory B (FXIII-B) subunits…”
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Shear-dependent morphology of von Willebrand factor bound to immobilized collagen
Published in Blood (15-03-2002)“…We have developed an immunogold von Willebrand factor (VWF) detection method that permits almost complete coverage of individual VWF molecules, and by this…”
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6
Cryptic Extensibility in von Willebrand Factor Revealed by Molecular Nanodissection
Published in International journal of molecular sciences (02-07-2024)“…Von Willebrand factor (VWF) is a multimer with a variable number of protomers, each of which is a head-to-head dimer of two multi-domain monomers. VWF responds…”
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Gravity sedimentation reveals functionally and morphologically different platelets in human blood
Published in Platelets (Edinburgh) (01-12-2024)“…In contrast to red blood cells, platelets float rather than sediment when a column of blood is placed in the gravitational field. By the analogy of erythrocyte…”
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Antithrombotic Effect of Platelet Glycoprotein Ib–Blocking Monoclonal Antibody Fab Fragments in Nonhuman Primates
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2000)“…Platelet adhesion in arterial blood flow is mainly supported by the platelet receptor glycoprotein (GP) Ib, which interacts with von Willebrand factor (vWF)…”
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9
Plasmin-driven fibrinolysis in a quasi-two-dimensional nanoscale fibrin matrix
Published in Journal of structural biology (01-09-2018)“…Fibrin plays a fundamentally important role during hemostasis. To withstand the shear forces of blood flow and prevent embolisation, fibrin monomers form a…”
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10
Structural hierarchy of mechanical extensibility in human von Willebrand factor multimers
Published in Protein science (01-01-2023)“…The von Willebrand factor (VWF) is a multimeric glycoprotein composed of 80‐ to 120‐nm‐long protomeric units and plays a fundamental role in mediating platelet…”
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Haptoglobin polymorphisms are associated with crohn's disease, disease behavior, and extraintestinal manifestations in hungarian patients
Published in Digestive diseases and sciences (01-05-2007)“…Functional differences and association with inflammatory disorders were found relating to three major haptoglobin (Hp) phenotypes. Our aim was to investigate…”
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12
Evaluation of commonly used tear sampling methods and their relevance in subsequent biochemical analysis
Published in Annals of clinical biochemistry (01-09-2017)“…The human precorneal tear film is a special body fluid, since it is a complex mixture of proteins, lipids, small bioactive molecules, and their concentrations…”
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13
Vascular Endothelial Growth Factor in Tear Samples of Patients with Systemic Sclerosis
Published in Mediators of Inflammation (01-01-2015)“…Background. Systemic sclerosis is an autoimmune disease, characterized by widespread small vessel vasculopathy, immune dysregulation with production of…”
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14
Protomer polymorphism in mechanically stretched von Willebrand factor
Published in Biophysical journal (11-02-2022)Get full text
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15
Von Willebrand Factor and Platelet Levels before Conditioning Chemotherapy Indicate Bone Marrow Regeneration following Autologous Hematopoietic Stem Cell Transplantation
Published in Transplantation and cellular therapy (01-12-2022)“…•Levels of von Willebrand factor (VWF) in both patient groups were the highest at engraftment during hematopoietic stem cell transplantation.•Platelet counts…”
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Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia
Published in Thrombosis and haemostasis (01-02-2009)“…The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes,…”
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Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure
Published in Thrombosis and haemostasis (01-09-2009)“…Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure…”
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18
Elevated Serum Cystatin C and Decreased Cathepsin S/Cystatin C Ratio Are Associated with Severe Peripheral Arterial Disease and Polyvascular Involvement
Published in Diagnostics (Basel) (28-03-2022)“…Peripheral arterial disease (PAD) is frequently associated with atherosclerotic manifestations of the carotids and coronaries. Polyvascular involvement and low…”
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The subendothelium of the HMEC-1 cell line supports thrombus formation in the absence of von Willebrand factor and collagen types I, III and VI
Published in Thrombosis and haemostasis (01-03-2001)“…The macromolecular composition of the extracellular matrix (ECM) produced by the human microvascular endothelial cell line (HMEC-1) was determined by ELISA and…”
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Thrombin generation and low-molecular-weight heparin prophylaxis in pregnant women with thrombophilia
Published in Thrombosis and haemostasis (01-02-2015)“…Pregnancy is associated with increased risk of venous thromboembolism, especially in the presence of thrombophilia. However, there is no consensus on the…”
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