Search Results - "Harsanyi, Michael C"

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    Cytotoxic effects of dihydroorotase inhibitors upon human CCRF-CEM leukemia by BROOKE, J, SZABADOS, E, LYONS, S. D, GOODRIDGE, R. J, HARSANYI, M. C, POINER, A, CHRISTOPHERSON, R. I

    Published in Cancer research (Chicago, Ill.) (15-12-1990)
    “…6-L-Thiodihydroorotate (TDHO) and 2-oxo-1,2,3,6-tetrahydropyrimidine-4,6-dicarboxylate (HDDP) are potent inhibitors of mammalian dihydroorotase in vitro (R. I…”
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    Mercaptan and dicarboxylate inhibitors of hamster dihydroorotase by Christopherson, Richard I, Schmalzl, Karl J, Szabados, Eve, Goodridge, Richard J, Harsanyi, Michael C, Sant, Melissa E, Algar, Elizabeth M, Anderson, Janet E, Armstrong, Alison

    Published in Biochemistry (Easton) (1989)
    “…In mammals, dihydroorotase is part of a trifunctional protein, dihydroorotate synthetase, which catalyzes the first three reactions of de novo pyrimidine…”
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    Chromatographic analysis of purine precursors in mouse L1210 leukemia by Sant, M E, Poiner, A, Harsanyi, M C, Lyons, S D, Christopherson, R I

    Published in Analytical biochemistry (01-10-1989)
    “…A number of antagonists of nucleotide metabolism with anti-cancer activity affect the de novo purine pathway. To determine the biochemical mechanisms of…”
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