Search Results - "Harroun, T A"

Spontaneously Formed Monodisperse Biomimetic Unilamellar Vesicles: The Effect of Charge, Dilution, and Time by Nieh, M.-P., Harroun, T.A., Raghunathan, V.A., Glinka, C.J., Katsaras, J.

“…Using small-angle neutron scattering and dynamic light scattering, we have constructed partial structural phase diagrams of lipid mixtures composed of the…”
Get full text

Concentration-independent spontaneously forming biomimetric vesicles by Nieh, M-P, Harroun, T A, Raghunathan, V A, Glinka, C J, Katsaras, J

“…In this Letter we present small-angle neutron scattering data from a biomimetic system composed of the phospholipids dimyristoyl and dihexanoyl…”
Get full text

Molecular dynamics simulations of a mixed DOPC/DOPG bilayer by Balali-Mood, K, Harroun, T A, Bradshaw, J P

“…We have constructed a mixed dioleoylphosphatidylcholine (DOPC) and dioleoylphosphatidylglycerol bilayer (DOPG) bilayer utilizing MD simulations. The aim was to…”
Get full text

Barrel-Stave Model or Toroidal Model? A Case Study on Melittin Pores by Yang, Lin, Harroun, Thad A., Weiss, Thomas M., Ding, Lai, Huang, Huey W.

“…Transmembrane pores induced by amphiphilic peptides, including melittin, are often modeled with the barrel-stave model after the alamethicin pore. We examine…”
Get full text

Finite-size effects do not reduce the repeat spacing of phospholipid multibilayer stacks on a rigid substrate by HARROUN, T. A, KOSLOWSKY, M, NIEH, M.-P, RAGHUNATHAN, V. A, KATSARAS, J

“…Finite-size effects in stacks of phospholipid bilayers, in the fluid L alpha phase, are investigated using samples oriented on silicon substrates. Recently in…”
Get full text

Membrane-bound ARF1 peptide: interpretation of neutron diffraction data by molecular dynamics simulation methods by Balali-Mood, K, Harroun, T A, Bradshaw, J P

“…Adenosine diphosphate ribosylation factor-1 (ARF1) is activated by cell membrane binding of a self-folding N-terminal domain. We have previously presented four…”
Get more information

Finite-size effects in biomimetic smectic films by Harroun, T A, Raghunathan, V A, Pencer, J, Nieh, M-P, Katsaras, J

“…Thin stacks of lipid multibilayers supported on rigid silicon and mica substrates are found to exhibit finite-size effects. Using neutron diffraction we find…”
Get full text

Membrane Pores Induced by Magainin by Ludtke, Steve J, He, Ke, Heller, William T, Harroun, Thad A, Yang, Lin, Huang, Huey W

“…Magainin, found in the skin of Xenopus laevis, belongs to a broad class of antimicrobial peptides which kill bacteria by permeabilizing the cytoplasmic…”
Get full text

Experimental Evidence for Hydrophobic Matching and Membrane-Mediated Interactions in Lipid Bilayers Containing Gramicidin by Harroun, Thad A., Heller, William T., Weiss, Thomas M., Yang, Lin, Huang, Huey W.

“…Hydrophobic matching, in which transmembrane proteins cause the surrounding lipid bilayer to adjust its hydrocarbon thickness to match the length of the…”
Get full text

Membrane Thinning Effect of the β-Sheet Antimicrobial Protegrin by Heller, William T, Waring, Alan J, Lehrer, Robert I, Harroun, Thad A, Weiss, Thomas M, Yang, Lin, Huang, Huey W

“…Lipid bilayers containing the antimicrobial peptide protegrin-1 (PG-1) were studied by lamellar X-ray diffraction. Previously, we have shown that the peptide…”
Get full text

Relationship between the unbinding and main transition temperatures of phospholipid bilayers under pressure by Harroun, T A, Nieh, M-P, Watson, M J, Raghunathan, V A, Pabst, G, Morrow, M R, Katsaras, J

“…Using neutron diffraction and a specially constructed high pressure cell suitable for aligned multibilayer systems, we have studied, as a function of pressure,…”
Get full text

Theoretical Analysis of Hydrophobic Matching and Membrane-Mediated Interactions in Lipid Bilayers Containing Gramicidin by Harroun, Thad A., Heller, William T., Weiss, Thomas M., Yang, Lin, Huang, Huey W.

“…We present a quantitative analysis of the effects of hydrophobic matching and membrane-mediated protein-protein interactions exhibited by gramicidin embedded…”
Get full text

Inhibitors can arrest the membrane activity of human islet amyloid polypeptide independently of amyloid formation by Harroun, Thad A., Bradshaw, Jeremy P., Ashley, Richard H.

“…Human islet amyloid polypeptide (hIAPP), co-secreted with insulin from pancreatic β cells, misfolds to form amyloid deposits in non-insulin-dependent diabetes…”
Get full text

Effect of changing the size of lipid headgroup on peptide insertion into membranes by Heller, W.T., He, K., Ludtke, S.J., Harroun, T.A., Huang, H.W.

“…Adsorption of amphiphilic peptides to the headgroup region of a lipid bilayer is a common mode of protein-membrane interactions. Previous studies have shown…”
Get full text

Supramolecular Structures of Peptide Assemblies in Membranes by Neutron Off-Plane Scattering: Method of Analysis by Yang, Lin, Weiss, Thomas M., Harroun, Thad A., Heller, William T., Huang, Huey W.

“…In a previous paper (Yang et al., Biophys. J. 75:641–645, 1998), we showed a simple, efficient method of recording the diffraction patterns of supramolecular…”
Get full text

Neutron Off-Plane Scattering of Aligned Membranes. I. Method of Measurement by Yang, Lin, Harroun, Thad A., Heller, William T., Weiss, Thomas M., Huang, Huey W.

“…We describe a method of measuring neutron scattering of aligned membranes with the momentum transfer oriented parallel or partly perpendicular to the plane of…”
Get full text

Cholesterol Hydroxyl Group Is Found To Reside in the Center of a Polyunsaturated Lipid Membrane by Harroun, Thad A, Katsaras, John, Wassall, Stephen R

“…Cholesterol and saturated lipid species preferentially partition into liquid ordered microdomains, such as lipid rafts, away from unsaturated lipid species for…”
Get full text

Oblique Membrane Insertion of Viral Fusion Peptide Probed by Neutron Diffraction by Bradshaw, Jeremy P, Darkes, Malcolm J. M, Harroun, Thad A, Katsaras, John, Epand, Richard M

“…Fusion peptides mimic the membrane fusion activities of the larger viral proteins from which they derive their sequences. A possible mode of activity involves…”
Get full text

Bilayer thickness and thermal response of dimyristoylphosphatidylcholine unilamellar vesicles containing cholesterol, ergosterol and lanosterol: A small-angle neutron scattering study by Pencer, Jeremy, Nieh, Mu-Ping, Harroun, Thad A., Krueger, Susan, Adams, Carl, Katsaras, John

“…Small-angle neutron scattering (SANS) measurements are performed on pure dimyristoyl phosphatidylcholine (DMPC) unilamellar vesicles (ULV) and those containing…”
Get full text

Magnetically Alignable Phase of Phospholipid “Bicelle” Mixtures Is a Chiral Nematic Made Up of Wormlike Micelles by Nieh, Mu-Ping, Raghunathan, V. A, Glinka, Charles J, Harroun, Thad A, Pabst, Georg, Katsaras, John

“…We have studied the phase behavior of binary mixtures of long- and short-chain lipids, namely, dimyristoyl phosphatidylcholine (DMPC) and dihexanoyl…”
Get full text