Search Results - "Harroch, S"

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    Pyk2 Regulates Multiple Signaling Events Crucial for Macrophage Morphology and Migration by Okigaki, M., Davis, C., Falasca, M., Harroch, S., Felsenfeld, D. P., Sheetz, M. P., Schlessinger, J.

    “…The biological role of the protein tyrosine kinase, Pyk2, was explored by targeting the Pyk2 gene by homologous recombination. Pyk2-/- mice are viable and…”
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    Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene by Buxbaum, J D, Georgieva, L, Young, J J, Plescia, C, Kajiwara, Y, Jiang, Y, Moskvina, V, Norton, N, Peirce, T, Williams, H, Craddock, N J, Carroll, L, Corfas, G, Davis, K L, Owen, M J, Harroch, S, Sakurai, T, O'Donovan, M C

    Published in Molecular psychiatry (01-02-2008)
    “…Neuregulin and the neuregulin receptor ERBB4 have been genetically and functionally implicated in schizophrenia. In this study, we used the yeast two-hybrid…”
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    Monoclonal antibody Cat-315 detects a glycoform of receptor protein tyrosine phosphatase beta/phosphacan early in CNS development that localizes to extrasynaptic sites prior to synapse formation by Dino, M.R., Harroch, S., Hockfield, S., Matthews, R.T.

    Published in Neuroscience (03-11-2006)
    “…Perineuronal nets (PNs) are lattice-like condensations of the extracellular matrix (ECM) that envelop synapses and decorate the surface of subsets of neurons…”
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    BACE (β-secretase) modulates the processing of APLP2 in vivo by Pastorino, L, Ikin, A.F, Lamprianou, S, Vacaresse, N, Revelli, J.P, Platt, K, Paganetti, P, Mathews, P.M, Harroch, S, Buxbaum, J.D

    Published in Molecular and cellular neuroscience (01-04-2004)
    “…BACE is an aspartyl protease that cleaves the amyloid precursor protein (APP) at the β-secretase cleavage site and is involved in Alzheimer's disease. The aim…”
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    No Obvious Abnormality in Mice Deficient in Receptor Protein Tyrosine Phosphatase β by Harroch, S., Palmeri, M., Rosenbluth, J., Custer, A., Okigaki, M., Shrager, P., Blum, M., Buxbaum, J. D., Schlessinger, J.

    Published in Molecular and Cellular Biology (01-10-2000)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    The protein tyrosine phosphatase Rptpζ is expressed in differentiated osteoblasts and affects bone formation in mice by Schinke, T, Gebauer, M, Schilling, A.F, Lamprianou, S, Priemel, M, Mueldner, C, Neunaber, C, Streichert, T, Ignatius, A, Harroch, S, Amling, M

    Published in Bone (New York, N.Y.) (01-03-2008)
    “…Abstract Tyrosine phosphorylation of intracellular substrates is one mechanism to regulate cellular proliferation and differentiation. Protein tyrosine…”
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    Receptor protein tyrosine phosphatases are expressed by cycling retinal progenitor cells and involved in neuronal development of mouse retina by Horvat-Bröcker, A, Reinhard, J, Illes, S, Paech, T, Zoidl, G, Harroch, S, Distler, C, Knyazev, P, Ullrich, A, Faissner, A

    Published in Neuroscience (27-03-2008)
    “…Abstract Receptor protein tyrosine phosphatases (RPTPs) appear to coordinate many aspects of neural development, including cell proliferation, migration and…”
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    Differential tyrosine phosphorylation of the IFNAR chain of the type I interferon receptor and of an associated surface protein in response to IFN‐alpha and IFN‐beta by Abramovich, C., Shulman, L.M., Ratovitski, E., Harroch, S., Tovey, M., Eid, P., Revel, M.

    Published in The EMBO journal (15-12-1994)
    “…The human interferon alpha‐receptor (IFNAR gene product) is a transmembranal protein of 557 amino acids with an intracytoplasmic domain of 100 amino acids…”
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    Induction by interleukin‐6 of interferon regulatory factor 1 (IRF‐1) gene expression through the palindromic interferon response element pIRE and cell type‐dependent control of IRF‐1 binding to DNA by Harroch, S., Revel, M., Chebath, J.

    Published in The EMBO journal (15-04-1994)
    “…The effects of interleukin‐6 (IL‐6) on interferon regulatory factor 1 (IRF‐1) gene expression were studied in B‐hybridoma B9 cells which are growth‐stimulated…”
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    Interleukin-6 signaling via four transcription factors binding palindromic enhancers of different genes by Harroch, S, Revel, M, Chebath, J

    Published in The Journal of biological chemistry (21-10-1994)
    “…Interferons (IFNs), as well as some interleukins, growth factors, and hormones, all induce tyrosine phosphorylation of STAT1 and additional transcription…”
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    Unmasking by soluble IL-6 receptor of IL-6 effect on metastatic melanoma : growth inhibition and differentiation of B16-F10.9 tumor cells by OH, J.-W, KATZ, A, HARROCH, S, EISENBACH, L, REVEL, M, CHEBATH, J

    Published in Oncogene (31-07-1997)
    “…Interleukin-6 (IL-6) inhibits the growth of melanocytes and of early stage melanoma cells, but not that of advanced melanoma cells. The in vitro IL-6 response…”
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    Antagonism of interferon beta on interferon gamma: inhibition of signal transduction in vitro and reduction of serum levels in multiple sclerosis patients by Revel, M, Chebath, J, Mangelus, M, Harroch, S, Moviglia, G A

    Published in Multiple sclerosis (1995)
    “…Interferon gamma (IFN-gamma acts as a mediator of multiple sclerosis (MS) exacerbations through a number of biological effects, such as induction of major…”
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    Interleukin-6 activates and regulates transcription factors of the interferon regulatory factor family in M1 cells by HARROCH, S, GOTHELF, Y, WATANABE, N, REVEL, M, CHEBATH, J

    Published in The Journal of biological chemistry (25-04-1993)
    “…Activation of (2'-5') A synthetase gene expression in interleukin-6 (IL-6)-treated myeloleukemic M1 cells correlates with protein binding to the interferon…”
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    A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions by Brueck, Wolfgang, Schlessinger, Joseph, Lafaille, Juan, Chao, Moses, Harroch, Sheila, Furtado, Glaucia C, Rosenbluth, Jack, Buxbaum, Joseph D

    Published in Nature genetics (01-11-2002)
    “…Several lines of evidence suggest that tyrosine phosphorylation is a key element in myelin formation, differentiation of oligodendrocytes and Schwann cells,…”
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    Receptor protein tyrosine phosphatase from stem cells to mature glial cells of the central nervous system by Lamprianou, Smaragda, Harroch, Sheila

    Published in Journal of molecular neuroscience (01-01-2006)
    “…The cornerstone of cell signaling is largely based on the phosphorylation state that is defined by the equilibrium of the activity of protein kinases and…”
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    The protein tyrosine phosphatase Rptpzeta is expressed in differentiated osteoblasts and affects bone formation in mice by Schinke, T, Gebauer, M, Schilling, A F, Lamprianou, S, Priemel, M, Mueldner, C, Neunaber, C, Streichert, T, Ignatius, A, Harroch, S, Amling, M

    Published in Bone (New York, N.Y.) (01-03-2008)
    “…Tyrosine phosphorylation of intracellular substrates is one mechanism to regulate cellular proliferation and differentiation. Protein tyrosine phosphatases…”
    Get full text
    Journal Article