Search Results - "Harrison, William T."

Sequential Nucleophilic Aromatic Substitution Reactions of Activated Halogens by Plater, M John, Harrison, William T A

“…Building blocks have been identified that can be functionalised by sequential nucleophilic aromatic substitution. Some examples are reported that involve the…”
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Chiral Thianthrenes by Plater, M John, Harrison, William T A

“…The absolute configuration and stability of two thianthrene chiral sulfoxides has been determined by means of X-ray single-crystal structure determinations…”
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Three‐year‐old with severe‐combined immunodeficiency and a mildly expansile T2/FLAIR signal abnormality by Smith, Vanessa L., Harrison, William T.

“…In 2005, natalizumab treatment was identified as a risk factor for PML in multiple sclerosis []. CONFLICT OF INTEREST STATEMENT The authors declare no conflict…”
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3‑Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation by Testa, Andrea, Lucas, Xavier, Castro, Guilherme V, Chan, Kwok-Ho, Wright, Jane E, Runcie, Andrew C, Gadd, Morgan S, Harrison, William T. A, Ko, Eun-Jung, Fletcher, Daniel, Ciulli, Alessio

“…Hydroxylation and fluorination of proline alters the pyrrolidine ring pucker and the trans:cis amide bond ratio in a stereochemistry-dependent fashion,…”
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The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators by Tseng, Chih-Chung, Baillie, Gemma, Donvito, Giulia, Mustafa, Mohammed A, Juola, Sophie E, Zanato, Chiara, Massarenti, Chiara, Dall’Angelo, Sergio, Harrison, William T. A, Lichtman, Aron H, Ross, Ruth A, Zanda, Matteo, Greig, Iain R

“…The first generation of CB1 positive allosteric modulators (e.g., ZCZ011) featured a 3-nitroalkyl-2-phenyl-indole structure. Although a small number of drugs…”
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Diverse Metabolic Profiles of a Streptomyces Strain Isolated from a Hyper-arid Environment by Rateb, Mostafa E, Houssen, Wael E, Harrison, William T. A, Deng, Hai, Okoro, Chinyere K, Asenjo, Juan A, Andrews, Barbara A, Bull, Alan T, Goodfellow, Michael, Ebel, Rainer, Jaspars, Marcel

“…The metabolic profile of Streptomyces sp. strain C34, isolated from the Chilean hyper-arid Atacama Desert soil, is dependent on the culture media used for its…”
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Fatal Granulomatous Amebic Encephalitis in a Heart Transplant Patient: Clinical, Radiographic, and Autopsy Findings by Harrison, William T, Lecky, Bruce, Hulette, Christine M

“…Abstract Granulomatous amebic encephalitis is a rare necrotizing infection of the CNS that occurs most commonly in immunocompromised individuals and is usually…”
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Synthesis, crystal structures and, magnetic and photoluminescence properties of lanthanide-based metal-organic frameworks constructed with 2,5-dihydroxybenzene-1,4-dicarboxylic acid by Hussain, Sajjad, Chen, Xuenian, Harrison, William T. A, Ahmad, Saeed, Sharif, Shahzad, Su, Jian, Muhammad, Shabbir, Li, Shujun

“…Four new lanthanide( iii ) coordination polymers ( 1-4 ) have been synthesized by using 2,5-dihydroxybenzene-1,4-dicarboxylate (Dhbdc, C 8 H 6 O 6 2− ) as a…”
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New palladium(II) and platinum(II) 5,5-diethylbarbiturate complexes with 2-phenylpyridine, 2,2'-bipyridine and 2,2'-dipyridylamine: synthesis, structures, DNA binding, molecular docking, cellular uptake, antioxidant activity and cytotoxicity by Icsel, Ceyda, Yilmaz, Veysel T, Kaya, Yunus, Samli, Hale, Harrison, William T A, Buyukgungor, Orhan

“…Novel palladium(ii) and platinum(ii) complexes of 5,5-diethylbarbiturate (barb) with 2-phenylpyridine (Hppy), 2,2'-bipyridine (bpy) and 2,2'-dipyridylamine…”
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Chaxamycins A–D, Bioactive Ansamycins from a Hyper-arid Desert Streptomyces sp by Rateb, Mostafa E, Houssen, Wael E, Arnold, Markus, Abdelrahman, Mostafa H, Deng, Hai, Harrison, William T. A, Okoro, Chinyere K, Asenjo, Juan A, Andrews, Barbara A, Ferguson, Gail, Bull, Alan T, Goodfellow, Michael, Ebel, Rainer, Jaspars, Marcel

“…Streptomyces sp. strain C34, isolated from soil collected in the Chilean hyper-arid Atacama Desert, was cultured on different media, resulting in the isolation…”
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Porous and Close Packed Supramolecular Assemblies from 2,4-Difluoronitrobenzene with Three Different Linkers and an n-Butylamine Cap by Plater, M. John, Esslemont, Abbie J., Harrison, William T. A.

“…A porous structure formed from sheets with cavities and two close packed structures were crystallised from building blocks prepared from…”
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11-Hydroxy-7-Methoxy-2,8-Dimethyltetracene-5,12-Dione by Astakala, Rishi Vachaspathy, Preet, Gagan, Haj Hasan, Ahlam, Desai, Ria, Asenjo, Juan A, Andrews, Barbara, Harrison, William T. A, Ebel, Rainer, Jaspars, Marcel

“…Microorganisms are a valuable source of pharmaceutically active chemicals, serving as scaffolds for synthesis as well as lead structures. Investigating novel…”
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Crystalline Forms of Trazodone Dihydrates by Plater, M. John, Harrison, William T. A.

“…In this study, treatment of anhydrous trazodone powder with ammonium carbamate in warm water crystallised two new polymorphs or dihydrates of trazodone after 5…”
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Correction to “3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation” by Testa, Andrea, Lucas, Xavier, Castro, Guilherme V, Chan, Kwok-Ho, Wright, Jane E, Runcie, Andrew C, Gadd, Morgan S, Harrison, William T. A, Ko, Eun-Jung, Fletcher, Daniel, Ciulli, Alessio

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Syntheses and Crystal Structures of Three Chiral Oxazolidinones with Different Ring Conformations by Soru, Ester, Cairney, Grace, Storey, John M. D, Harrison, William T. A

“…The preparation of new, enantiomerically pure, α-amino acids from easily available starting materials is an ongoing challenge in synthetic organic chemistry…”
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Short I⋯O Interactions in the Crystal Structures of Two 2-Iodo-Phenyl Methyl-Amides as Substrates for Radical Translocation Reactions by Ishaq, Ahtsham, Storey, John M. D., Harrison, William T. A.

“…Radical translocation reactions are finding various uses in organic synthesis, in particular the stereospecific formation of complex natural products. In this…”
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New Functionalized Phenoxazines and Phenothiazines by Plater, M. John, Harrison, William T. A.

“…The reaction of either 2-aminophenol or 2-(N-methylamino)phenol with 1,2-difluoro-4,5-dinitrobenzene and sodium carbonate in EtOH gives…”
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Synthesis, Thermal, Structural Analyses, and Photoluminescent Properties of a New Family of Malonate-Containing Lanthanide(III) Coordination Polymers by Hussain, Sajjad, Chen, Xuenian, Harrison, William T A, Ahmad, Saeed, Elsegood, Mark R J, Khan, Islam Ullah, Muhammad, Shabbir

“…Five new Lanthanide(III) complexes of malonic acid (HOOC-CH -COOH); {[Gd(C H O )(H O) ]·NO } ( ), {[Tb(C H O )(H O) ]·NO } ( ), {[Ho(C H O )(H O) ]·NO } ( ),…”
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A Potential Iterative Approach to 1,4‐Dihydro‐N‐Heteroacene Arrays by Plater, M. John, Harrison, William T. A.

“…A new method for the synthesis of substituted 1,4‐dihydrophenazines is reported and the structure of N‐butyl‐5‐methyl‐3‐nitro‐5,10‐dihydrophenazine is proven…”
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Photochemical Fragmentation of Irgacure PAG 103 by Plater, M. John, Harrison, William T. A, Raab, Andrea

“…Photoisomerization of Irgacure PAG 103 followed by photocyclization and fragmentation leads to three tricyclic thieno­[2,3-b]­quinoline-4-carbonitrile…”
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