Search Results - "Harrison, Timothy G"

Dynamics and impact of homologous recombination on the evolution of Legionella pneumophila by David, Sophia, Sánchez-Busó, Leonor, Harris, Simon R, Marttinen, Pekka, Rusniok, Christophe, Buchrieser, Carmen, Harrison, Timothy G, Parkhill, Julian

“…Legionella pneumophila is an environmental bacterium and the causative agent of Legionnaires' disease. Previous genomic studies have shown that recombination…”
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Whole genome sequencing of Streptococcus pneumoniae: development, evaluation and verification of targets for serogroup and serotype prediction using an automated pipeline by Kapatai, Georgia, Sheppard, Carmen L, Al-Shahib, Ali, Litt, David J, Underwood, Anthony P, Harrison, Timothy G, Fry, Norman K

“…Streptococcus pneumoniae typically express one of 92 serologically distinct capsule polysaccharide (cps) types (serotypes). Some of these serotypes are closely…”
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Consensus Sequence-Based Scheme for Epidemiological Typing of Clinical and Environmental Isolates of Legionella pneumophila by Gaia, Valeria, Fry, Norman K, Afshar, Baharak, Lůck, P. Christian, Meugnier, Hélène, Etienne, Jerome, Peduzzi, Raffaele, Harrison, Timothy G

“…A previously described sequence-based epidemiological typing method for clinical and environmental isolates of Legionella pneumophila serogroup 1 was extended…”
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Correction: Dynamics and impact of homologous recombination on the evolution of Legionella pneumophila by David, Sophia, Sánchez-Busó, Leonor, Harris, Simon R, Marttinen, Pekka, Rusniok, Christophe, Buchrieser, Carmen, Harrison, Timothy G, Parkhill, Julian

“…[This corrects the article DOI: 10.1371/journal.pgen.1006855.]…”
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Legionella pneumophila Strain 130b Possesses a Unique Combination of Type IV Secretion Systems and Novel Dot/Icm Secretion System Effector Proteins by SCHROEDER, Gunnar N, PETTY, Nicola K, BEATSON, Scott A, DOUGAN, Gordon, HARTLAND, Elizabeth L, FRANKEL, Gad, MOUSNIER, Aurélie, HARDING, Clare R, VOGRIN, Adam J, WEE, Bryan, FRY, Norman K, HARRISON, Timothy G, NEWTON, Hayley J, THOMSON, Nicholas R

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Comparison of the Legionella pneumophila population structure as determined by sequence-based typing and whole genome sequencing by Underwood, Anthony P, Jones, Garan, Mentasti, Massimo, Fry, Norman K, Harrison, Timothy G

“…Legionella pneumophila is an opportunistic pathogen of humans where the source of infection is usually from contaminated man-made water systems. When an…”
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Oral fluid testing for pertussis, England and wales, june 2007-august 2009 by Campbell, Helen, Amirthalingam, Gayatri, Fry, Norman K, Litt, David, Harrison, Timothy G, Wagner, Karen, Crowcroft, Natasha S, Miller, Elizabeth

“…Existing pertussis surveillance systems tend to underidentify less severe cases among older children and adults. For routine follow-up of notified,…”
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Rapid investigation of cases and clusters of Legionnaires' disease in England and Wales using direct molecular typing by Mentasti, Massimo, Afshar, Baharak, Collins, Samuel, Walker, Jimmy, Harrison, Timothy G, Chalker, Vicki

“…Legionella pneumophila is the leading cause of Legionnaires' disease, a severe pneumonia that can occur as sporadic cases or point-source outbreaks affecting…”
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Diagnosis of Streptococcus pneumoniae Infections in Adults with Bacteremia and Community-Acquired Pneumonia: Clinical Comparison of Pneumococcal PCR and Urinary Antigen Detection by Smith, Michael D, Sheppard, Carmen L, Hogan, Angela, Harrison, Timothy G, Dance, David A.B, Derrington, Petra, George, Robert C

“…The diagnosis of severe Streptococcus pneumoniae infection relies heavily on insensitive culture techniques. To improve the usefulness of PCR assays, we…”
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Montelukast for postinfectious cough in adults: a double-blind randomised placebo-controlled trial by Wang, Kay, Dr, Birring, Surinder S, MD, Taylor, Kathryn, PhD, Fry, Norman K, PhD, Hay, Alastair D, Prof, Moore, Michael, FRCGP, Jin, Jing, PhD, Perera, Rafael, DPhil, Farmer, Andrew, Prof, Little, Paul, Prof, Harrison, Timothy G, PhD, Mant, David, Prof, Harnden, Anthony, FRCGP

“…Summary Background Postinfectious cough is common in primary care, but has no proven effective treatments. Cysteinyl leukotrienes are involved in the…”
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Role of PCR in the diagnosis of pertussis infection in infants: 5 years' experience of provision of a same-day real-time PCR service in England and Wales from 2002 to 2007 by Fry, Norman K, Duncan, John, Wagner, Karen, Tzivra, Oceanis, Doshi, Nita, Litt, David J, Crowcroft, Natasha, Miller, Elizabeth, George, Robert C, Harrison, Timothy G

“…1 Respiratory and Systemic Infection Laboratory, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London, UK 2 Immunisation, Hepatitis and…”
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Direct molecular typing of Bordetella pertussis from clinical specimens submitted for diagnostic quantitative (real-time) PCR by LITT, David J, JAUNEIKAITE, Elita, TCHIPEVA, Draga, HARRISON, Timothy G, FRY, Norman K

“…Molecular typing of Bordetella pertussis is routinely performed on bacterial isolates, but not on DNA extracted from nasopharyngeal aspirates or pernasal swabs…”
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Multilocus Sequence Typing of Bartonella henselae in the United Kingdom Indicates that Only a Few, Uncommon Sequence Types Are Associated with Zoonotic Disease by CHALONER, Gemma L, HARRISON, Timothy G, COYNE, Karen P, AANENSEN, David M, BIRTLES, Richard J

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Clinical Utility of Urinary Antigen Detection for Diagnosis of Community-Acquired, Travel-Associated, and Nosocomial Legionnaires' Disease by HELBIG, Jürgen H, ULDUM, Søren A, BERNANDER, Sverker, LÜCK, Paul Christian, WEWALKA, Günther, ABRAHAM, Bill, GAIA, Valeria, HARRISON, Timothy G

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Sequence-Based Typing of Legionella pneumophila Serogroup 1 Offers the Potential for True Portability in Legionellosis Outbreak Investigation by GAIA, Valeria, FRY, Norman K, HARRISON, Timothy G, PEDUZZI, Raffaele

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Pneumococcal carriage in children and adults two years after introduction of the thirteen valent pneumococcal conjugate vaccine in England by van Hoek, Albert Jan, Sheppard, Carmen L, Andrews, Nick J, Waight, Pauline A, Slack, Mary P.E, Harrison, Timothy G, Ladhani, Shamez N, Miller, Elizabeth

“…Highlights • In April 2010 PCV7 was replaced by PCV13. • We investigated pneumococcal carriage in children and their household contacts. • Carriage of PCV13…”
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Chemical Science Research, Elementary School Children and Their Teachers Are More Closely Related than You May Imagine: The “I Bet You Did Not Know” Project by Trew, Alison J., Early, Craig, Ellis, Rebecca, Nash, Julia, Pemberton, Katharine, Tyler, Paul, Harrison, Timothy G., Shallcross, Dudley E.

“…Topics associated with the chemical sciences form a significant part of the curriculum in science at the primary school level in the U.K. In this methodology…”
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Development, validation and implementation of a quadruplex real-time PCR assay for identification of potentially toxigenic corynebacteria by De Zoysa, Aruni, Efstratiou, Androulla, Mann, Ginder, Harrison, Timothy G, Fry, Norman K

“…Toxigenic corynebacteria are uncommon in the UK; however, laboratory confirmation by the national reference laboratory can inform public health action…”
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Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently by David, Sophia, Rusniok, Christophe, Mentasti, Massimo, Gomez-Valero, Laura, Harris, Simon R, Lechat, Pierre, Lees, John, Ginevra, Christophe, Glaser, Philippe, Ma, Laurence, Bouchier, Christiane, Underwood, Anthony, Jarraud, Sophie, Harrison, Timothy G, Parkhill, Julian, Buchrieser, Carmen

“…Legionella pneumophila is an environmental bacterium and the leading cause of Legionnaires' disease. Just five sequence types (ST), from more than 2000…”
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Evaluation of an Optimal Epidemiological Typing Scheme for Legionella pneumophila with Whole-Genome Sequence Data Using Validation Guidelines by David, Sophia, Mentasti, Massimo, Tewolde, Rediat, Aslett, Martin, Harris, Simon R, Afshar, Baharak, Underwood, Anthony, Fry, Norman K, Parkhill, Julian, Harrison, Timothy G

“…Sequence-based typing (SBT), analogous to multilocus sequence typing (MLST), is the current "gold standard" typing method for investigation of legionellosis…”
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