Search Results - "Harrison, Peter T"
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Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer
Published in Seminars in cancer biology (01-04-2020)“…Epidermal growth factor receptor (EGFR) mutations are the second most common oncogenic driver event in non-small cell lung cancer (NSCLC). Classical activating…”
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Exploiting vulnerabilities in cancer signalling networks to combat targeted therapy resistance
Published in Essays in biochemistry (26-10-2018)“…Drug resistance remains one of the greatest challenges facing precision oncology today. Despite the vast array of resistance mechanisms that cancer cells…”
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A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts
Published in Disease models & mechanisms (14-07-2020)“…SWATH-mass spectrometry (MS) enables accurate and reproducible proteomic profiling in multiple model organisms including the mouse. Here, we present a…”
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Spatial localisation of Discoidin Domain Receptor 2 (DDR2) signalling is dependent on its collagen binding and kinase activity
Published in Biochemical and biophysical research communications (18-06-2018)“…Discoidin Domain Receptor 2 (DDR2) is a collagen-binding receptor tyrosine kinase that initiates delayed and sustained tyrosine phosphorylation signalling. To…”
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Corrigendum to “Spatial localisation of Discoidin Domain Receptor 2 (DDR2) signalling is dependent on its collagen binding and kinase activity” [Biochem. Biophys. Res. Commun. 501 (1) (18 June 2018) 124–130]
Published in Biochemical and biophysical research communications (26-09-2018)Get full text
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A mouse SWATH-MS reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts
Published in Disease models & mechanisms (01-01-2020)“…SWATH-mass spectrometry (MS) enables accurate and reproducible proteomic profiling in multiple model organisms including the mouse. Here we present a…”
Get full text
Journal Article