Search Results - "Harrison, Michael R M"

Activation of a transient progenitor state in the epicardium is required for zebrafish heart regeneration by Xia, Yu, Duca, Sierra, Perder, Björn, Dündar, Friederike, Zumbo, Paul, Qiu, Miaoyan, Yao, Jun, Cao, Yingxi, Harrison, Michael R. M., Zangi, Lior, Betel, Doron, Cao, Jingli

“…The epicardium, a mesothelial cell tissue that encompasses vertebrate hearts, supports heart regeneration after injury through paracrine effects and as a…”
Get full text

The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos by Harrison, Michael R M, Georgiou, Aristophanes S, Spaink, Herman P, Cunliffe, Vincent T

“…The epigenetic regulator Histone Deacetylase 1 (Hdac1) is required for specification and patterning of neurones and myelinating glia during development of the…”
Get full text

Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures by Baxendale, Sarah, Holdsworth, Celia J, Meza Santoscoy, Paola L, Harrison, Michael R M, Fox, James, Parkin, Caroline A, Ingham, Philip W, Cunliffe, Vincent T

“…The availability of animal models of epileptic seizures provides opportunities to identify novel anticonvulsants for the treatment of people with epilepsy. We…”
Get full text

The Lymphatic System in Zebrafish Heart Development, Regeneration and Disease Modeling by Feng, Xidi, Travisano, Stanislao, Pearson, Caroline A, Lien, Ching-Ling, Harrison, Michael R M

“…Heart disease remains the single largest cause of death in developed countries, and novel therapeutic interventions are desperately needed to alleviate this…”
Get full text

Heterogeneous pdgfrb+ cells regulate coronary vessel development and revascularization during heart regeneration by Kapuria, Subir, Bai, Haipeng, Fierros, Juancarlos, Huang, Ying, Ma, Feiyang, Yoshida, Tyler, Aguayo, Antonio, Kok, Fatma, Wiens, Katie M, Yip, Joycelyn K, McCain, Megan L, Pellegrini, Matteo, Nagashima, Mikiko, Hitchcock, Peter F, Mochizuki, Naoki, Lawson, Nathan D, Harrison, Michael M R, Lien, Ching-Ling

“…Endothelial cells emerge from the atrioventricular canal to form coronary blood vessels in juvenile zebrafish hearts. We find that pdgfrb is first expressed in…”
Get full text

Single-nuclei multiomic analyses identify human cardiac lymphatic endothelial cells associated with coronary arteries in the epicardium by Travisano, Stanislao Igor, Harrison, Michael R.M., Thornton, Matthew E., Grubbs, Brendan H., Quertermous, Thomas, Lien, Ching-Ling

“…Cardiac lymphatic vessels play important roles in fluid homeostasis, inflammation, disease, and regeneration of the heart. The developing cardiac lymphatics in…”
Get full text

Late developing cardiac lymphatic vasculature supports adult zebrafish heart function and regeneration by Harrison, Michael Rm, Feng, Xidi, Mo, Guqin, Aguayo, Antonio, Villafuerte, Jessi, Yoshida, Tyler, Pearson, Caroline A, Schulte-Merker, Stefan, Lien, Ching-Ling

“…The cardiac lymphatic vascular system and its potentially critical functions in heart patients have been largely underappreciated, in part due to a lack of…”
Get full text

Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance by Buth, Jessie E, Dyevich, Catherine E, Rubin, Alexandra, Wang, Chengbing, Gao, Lei, Marks, Tessa, Harrison, Michael RM, Kong, Jennifer H, Ross, M Elizabeth, Novitch, Bennett G, Pearson, Caroline Alayne

“…Neural progenitor cells within the cerebral cortex undergo a characteristic switch between symmetric self-renewing cell divisions early in development and…”
Get full text

Chemokine-Guided Angiogenesis Directs Coronary Vasculature Formation in Zebrafish by Harrison, Michael R.M., Bussmann, Jeroen, Huang, Ying, Zhao, Long, Osorio, Arthela, Burns, C. Geoffrey, Burns, Caroline E., Sucov, Henry M., Siekmann, Arndt F., Lien, Ching-Ling

“…Interruption of the coronary blood supply severely impairs heart function with often fatal consequences for patients. However, the formation and maturation of…”
Get full text

Opposing actions of histone deacetylase 1 and Notch signalling restrict expression of erm and fgf20a to hindbrain rhombomere centres during zebrafish neurogenesis by Lightman, Elewys G, Harrison, Michael R M, Cunliffe, Vincent T

“…The rate and pattern of neurogenesis in the developing vertebrate nervous system is controlled by a complex interplay of intercellular signalling pathways and…”
Get full text

Methods for dynamic and whole volume imaging of the zebrafish heart by Bakis, Isaac, Sun, Yuhan, Abd Elmagid, Laila, Feng, Xidi, Garibyan, Mher, Yip, Joycelyn K., Yu, Fang Zhou, Chowdhary, Sayali, Fernandez, Gerardo Esteban, Cao, Jingli, McCain, Megan L., Lien, Ching-Ling, Harrison, Michael RM

“…Tissue development and regeneration are dynamic processes involving complex cell migration and cell-cell interactions. We have developed a protocol for…”
Get full text

Minimally Invasive Fetal Surgery by Graves, Claire E., MD, Harrison, Michael R., MD, Padilla, Benjamin E., MD

“…Fetal surgery corrects severe congenital anomalies in utero to prevent their severe consequences on fetal development. The significant risk of open fetal…”
Get full text

A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome by Crombleholme, Timothy M., MD, Shera, David, ScD, Lee, Hanmin, MD, Johnson, Mark, MD, D’Alton, Mary, MD, Porter, Flint, MD, Chyu, Jacquelyn, MD, Silver, Richard, MD, Abuhamad, Alfred, MD, Saade, George, MD, Shields, Laurence, MD, Kauffman, David, MD, Stone, Joanne, MD, Albanese, Craig T., MD, Bahado-Singh, Ray, MD, Ball, Robert H., MD, Bilaniuk, Larissa, MD, Coleman, Beverly, MD, Farmer, Diana, MD, Feldstein, Vickie, MD, Harrison, Michael R., MD, Hedrick, Holly, MD, Livingston, Jeffrey, MD, Lorenz, Robert P., MD, Miller, David A., MD, Norton, Mary E., MD, Polzin, William J., MD, Robinson, Julian N., MD, Rychik, Jack, MD, Sandberg, Per L., MD, Seri, Istvan, MD, Simon, Erin, MD, Simpson, Lynn L., MD, Yedigarova, Larisa, MD, Wilson, R. Douglas, MD, Young, Bruce, MD

“…Objective The objective of the study was to examine the effect of selective fetoscopic laser photocoagulation (SFLP) vs serial amnioreduction (AR) on perinatal…”
Get full text

Magnamosis II: Magnetic Compression Anastomosis for Minimally Invasive Gastrojejunostomy and Jejunojejunostomy by Pichakron, Kullada O., MD, FACS, Jelin, Eric B., MD, Hirose, Shinjiro, MD, FACS, Curran, Patrick F., MS, Jamshidi, Ramin, MD, Stephenson, Jacob T., MD, Fechter, Richard, Strange, Michael, MS, Harrison, Michael R., MD, FACS

“…Background Previously we demonstrated the safety and patency of a magnetic compression anastomosis (magnamosis). We present the further development of this…”
Get full text

A History of Fetal Surgery by Jancelewicz, Tim, MD, Harrison, Michael R., MD

“…Over the past 3 decades, fetal surgery for congenital disease has evolved from merely a fanciful concept to a medical field in its own right. Techniques for…”
Get full text

Challenges and climate of business environment and resources to support pediatric device development by Iqbal, Corey W., MD, Wall, James, MD, Harrison, Michael R., MD

“…Abstract The incidence of pediatric disease conditions pales in comparison to adult disease. Consequently, many pediatric disorders are considered orphan…”
Get full text

Reliability of the lung-to-head ratio as a predictor of outcome in fetuses with isolated left congenital diaphragmatic hernia at gestation outside 24-26 weeks by Yang, Soon Ha, MD, PhD, Nobuhara, Kerilyn K., MD, Keller, Roberta L., MD, Ball, Robert H., MD, Goldstein, Ruth B., MD, Feldstein, Vickie A., MD, Callen, Peter W., MD, Filly, Roy A., MD, Farmer, Diana L., MD, Harrison, Michael R., MD, Lee, Hanmin, MD

“…Objective The purpose of this study was to investigate the relationship between lung-to-head ratio (LHR) and gestational age (GA) in fetuses with isolated left…”
Get full text