Search Results - "Harris, Ralph N."

Highly potent, non-basic 5-HT6 ligands. Site mutagenesis evidence for a second binding mode at 5-HT6 for antagonism by Harris, Ralph N., Stabler, Russel S., Repke, David B., Kress, James M., Walker, Keith A., Martin, Renee S., Brothers, Julie M., Ilnicka, Mariola, Lee, Simon W., Mirzadegan, Tara

“…A series of 5-HT6 ligands derived from (R)-1-(amino)methyl-6-(phenyl)sulfonyltetralin was prepared that yielded several neutral, non-basic analogs having…”
Get full text

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 2. Preparation and in vitro and in vivo evaluaton of 1-(alkoxymethyl)-2-[(hydroxyimino)methyl]-3-methylimidazolium halides for reactivation of organophosphorus-inhibited acetylcholinesterases by Bedford, Clifford D, Harris, Ralph N, Howd, Robert A, Goff, Dane A, Koolpe, Gary A, Petesch, M, Miller, Alexi, Nolen, Harold W, Musallam, H. A

Get full text

Structure-activity relationships for reactivators of organophosphorus-inhibited acetylcholinesterase: quaternary salts of 2[(hydroxyimino)methyl]imidazoles by Bedford, Clifford D, Harris, Ralph N, Howd, Robert A, Miller, Alexi, Nolen, Harold W, Kenley, Richard A

Get full text

The Meaning of Personal Identity by Harris, Ralph, N.

Get full text

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 4. Effect of various side-chain substituents on therapeutic activity against anticholinesterase intoxication by Goff, Dane A, Koolpe, Gary A, Kelson, Andrew B, Vu, Huynh M, Taylor, Dorris L, Bedford, Clifford D, Harris, Ralph N, Mussalam, H. A, Koplovitz, Irwin

“…A series of quaternary salt derivatives of 2-[(hydroxyimino)methyl]-1-methylimidazole incorporating various side chains bearing ether, silyl, nitrile, ester,…”
Get full text

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 5. Structure-activity relationships for side-chain nitro-, sulfone-, amino-, and aminosulfonyl-substituted analogs for therapy against anticholinesterase intoxication by Koolpe, Gary A, Lovejoy, Steven M, Goff, Dane A, Lin, Kuei Ying, Leung, Doris S, Bedford, Clifford D, Harris, Ralph N, Musallam, H. A, Koplovitz, Irwin

“…Several quaternary imidazolium oxime derivatives incorporating side chains bearing nitro, sulfone, amino, and aminosulfonyl substituents were prepared and…”
Get full text

Highly potent, non-basic 5-HT sub(6) ligands. Site mutagenesis evidence for a second binding mode at 5-HT sub(6) for antagonism by Harris, Ralph N, Stabler, Russel S, Repke, David B, Kress, James M, Walker, Keith A, Martin, Renee S, Brothers, Julie M, Ilnicka, Mariola, Lee, Simon W, Mirzadegan, Tara

“…A series of 5-HT sub(6) ligands derived from (R)-1-(amino)methyl-6-(phenyl)sulfonyltetralin was prepared that yielded several non-basic analogs having…”
Get full text

Cleavage of methoxymethyl ethers with boron trichloride. A convenient, versatile preparation of chloromethyl ether derivatives by Goff, Dane A, Harris, Ralph N, Bottaro, Jeffrey C, Bedford, Clifford D

Get full text

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 3. Synthesis and evaluation of (alkenyloxy)-, (alkynyloxy)-, and (aralykyloxy)methyl quaternarized 2-[(hydroxyimino)methyl]-1-alkylimidazolium halides as reactivators and therapy for soman intoxication by Bedford, Clifford D, Harris, Ralph N, Howd, Robert A, Goff, Dane A, Koolpe, Gary A, Petesch, M, Koplovitz, Irwin, Sultan, Walter E, Musallam, H. A

“…A series of structurally related monosubstituted 1-[(alkenyloxy)methyl]-, 1-[(alkynyloxy)methyl]-, and…”
Get full text

Structure-activity relationships for reactivators of organophosphorus-inhibited acetylcholinesterase: quaternary salts of 2-[(hydroxyimino)methyl]imidazole by BEDFORD, C. D, HARRIS, R. N. III, HOWD, R. A, MILLER, A, NOLEN, H. W. III, KENLEY, R. A

“…A series of 1,3-disubstituted-2-[(hydroxyimino)methyl]imidazolium halides were prepared and evaluated in vitro with respect to their ability to reactivate…”
Get full text