Search Results - "Harris, Patricia L."

Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib by Lynch, Thomas J, Bell, Daphne W, Sordella, Raffaella, Gurubhagavatula, Sarada, Okimoto, Ross A, Brannigan, Brian W, Harris, Patricia L, Haserlat, Sara M, Supko, Jeffrey G, Haluska, Frank G, Louis, David N, Christiani, David C, Settleman, Jeff, Haber, Daniel A

“…Gefitinib, an inhibitor of the tyrosine kinase of the epidermal growth factor receptor (EGFR), is effective in less than 20 percent of patients with…”
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Irreversible Inhibitors of the EGF Receptor May Circumvent Acquired Resistance to Gefitinib by Kwak, Eunice L., Sordella, Raffaella, Bell, Daphne W., Godin-Heymann, Nadia, Okimoto, Ross A., Brannigan, Brian W., Harris, Patricia L., Driscoll, David R., Fidias, Panos, Lynch, Thomas J., Rabindran, Sridhar K., McGinnis, John P., Wissner, Allan, Sharma, Sreenath V., Isselbacher, Kurt J., Settleman, Jeffrey, Haber, Daniel A.

“…Non-small cell lung cancers (NSCLCs) with activating mutations in the kinase domain of the epidermal growth factor receptor (EGFR) demonstrate dramatic, but…”
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Epidermal Growth Factor Receptor Mutations and Gene Amplification in Non–Small-Cell Lung Cancer: Molecular Analysis of the IDEAL/INTACT Gefitinib Trials by BELL, Daphne W, LYNCH, Thomas J, KREBS, Annetta D, JOHNSON, David H, GIACCONE, Gmseppe, HERBST, Roy S, MANEGOLD, Christian, FUKUOKA, Masahiro, KRIS, Mark G, BASELGA, José, OCHS, Judith S, HABER, Daniel A, HASERLAT, Sara M, HARRIS, Patricia L, OKIMOTO, Ross A, BRANNIGAN, Brian W, SGROI, Dennis C, MUIR, Beth, RIEMENSCHNEIDER, Markus J, IACONA, Renee Bailey

“…Most cases of non-small-cell lung cancer (NSCLC) with dramatic responses to gefitinib have specific activating mutations in the epidermal growth factor…”
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Epidermal Growth Factor Receptor Kinase Domain Mutations in Esophageal and Pancreatic Adenocarcinomas by KWAK, Eunice L, JANKOWSKI, Janusz, MUIR, Beth, SETTLEMAN, Jeff, FUCHS, Charles S, KULKE, Matthew H, RYAN, David P, CLARK, Jeff W, SGROI, Dennis C, HABER, Daniel A, BELL, Daphne W, THAYER, Sarah P, LAUWERS, Gregory Y, BRANNIGAN, Brian W, HARRIS, Patricia L, OKIMOTO, Ross A, HASERLAT, Sara M, DRISCOLL, David R, FERRY, David

“…Purpose: Specific activating mutations within the epidermal growth factor receptor ( EGFR ) identify a subset of non–small cell lung cancers with dramatic…”
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Healthcare-associated infections during the coronavirus disease 2019 (COVID-19) pandemic and the modulating effect of centralized surveillance by Snyder, Graham M, Wagester, Suzanne, Harris, Patricia L, Valek, Abby L, Hodges, Jacob C, Bilderback, Andrew L, Kader, Fazrina, Tanner, Colleen A, Metzger, Amy P, DiNucci, Susan E, Colaianne, Bonnie V, Chung, Ashley, Zapf, Rachel L, Kip, Paula L, Minnier, Tamra E

“…We analyzed efficacy of a centralized surveillance infection prevention (CSIP) program in a healthcare system on healthcare-associated infection (HAI) rates…”
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Development and implementation of a centralized surveillance infection prevention program in a multi-facility health system: A quality improvement project by Snyder, Graham M, Wagester, Suzanne, Harris, Patricia L, Valek, Abby L, Hodges, Jacob C, Bilderback, Andrew L, Kader, Fazrina, Tanner, Colleen A, Metzger, Amy P, DiNucci, Susan E, Colaianne, Bonnie V, Chung, Ashley, Zapf, Rachel L, Kip, Paula L, Minnier, Tamra E

“…To develop, implement, and evaluate the effectiveness of a unique centralized surveillance infection prevention (CSIP) program. Observational quality…”
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Response of Some Head and Neck Cancers to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors May Be Linked to Mutation of ERBB2 rather than EGFR by COHEN, Ezra E. W, LINGEN, Mark W, CLARK, John R, ROCCO, James W, VOKES, Everett E, HABER, Daniel A, BELL, Daphne W, MARTIN, Leslie E, HARRIS, Patricia L, BRANNIGAN, Brian W, HASERLAT, Sara M, OKIMOTO, Ross A, SGROI, Dennis C, DAHIYA, Sonika, MUIR, Beth

“…Purpose: Small-molecule tyrosine kinase inhibitors (TKI) of the epidermal growth factor receptor (EGFR) have shown modest yet reproducible response rates in…”
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Prevalence and Functional Analysis of Sequence Variants in the ATR Checkpoint Mediator Claspin by Zhang, Jianmin, Song, Young-Han, Brannigan, Brian W, Wahrer, Doke C R, Schiripo, Taryn A, Harris, Patricia L, Haserlat, Sara M, Ulkus, Lindsey E, Shannon, Kristen M, Garber, Judy E, Freedman, Matthew L, Henderson, Brian E, Zou, Lee, Sgroi, Dennis C, Haber, Daniel A, Bell, Daphne W

“…Mutational inactivation of genes controlling the DNA-damage response contributes to cancer susceptibility within families and within the general population as…”
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Water Cultures Are More Sensitive Than Swab Cultures for the Detection of Environmental Legionella by Decker, Brooke K, Harris, Patricia L, Toy, Diana L, Muder, Robert R, Sonel, Ali F, Clancy, Cornelius J

“…Water cultures were significantly more sensitive than concurrently collected swab cultures (n=2,147 each) in detecting Legionella pneumophila within a Veterans…”
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Improving the Diagnosis of Legionella Pneumonia within a Healthcare System through a Systematic Consultation and Testing Program by Decker, Brooke K, Harris, Patricia L, Muder, Robert R, Hong, Jae H, Singh, Nina, Sonel, Ali F, Clancy, Cornelius J

“…Legionella testing is not recommended for all patients with pneumonia, but rather for particular patient subgroups. As a result, the overall incidence of…”
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Identifying the Risk Factors for Hospital-Acquired Methicillin-Resistant Staphylococcus aureus (MRSA) Infection among Patients Colonized with MRSA on Admission by Fukuta, Yuriko, Cunningham, Candace A., Harris, Patricia L., Wagener, Marilyn M., Muder, Robert R.

“…Background. Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen in hospital-acquired infections. MRSA-colonized inpatients who may benefit…”
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Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts by Bell, Daphne W., Kim, Sang H., Godwin, Andrew K., Schiripo, Taryn A., Harris, Patricia L., Haserlat, Sara M., Wahrer, Doke C.R., Haiman, Christopher A., Daly, Mary B., Niendorf, Kristin B., Smith, Matthew R., Sgroi, Dennis C., Garber, Judy E., Olopade, Olufunmilayo I., Marchand, Loic Le, Henderson, Brian E., Altshuler, David, Haber, Daniel A., Freedman, Matthew L.

“…The CHEK2‐1100delC mutation is recurrent in the population and is a moderate risk factor for breast cancer. To identify additional CHEK2 mutations potentially…”
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Clinicians' perceptions of the problem of antimicrobial resistance in health care facilities by Giblin, Tara Bridget, Sinkowitz-Cochran, Ronda L, Harris, Patricia L, Jacobs, Sharon, Liberatore, Kathy, Palfreyman, Marsha A, Harrison, Edward I, Cardo, Denise M

“…Many clinicians do not comply with guidelines regarding antimicrobial resistance (AR). In response, the Centers for Disease Control and Prevention developed a…”
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Carbon-13 and proton nuclear magnetic resonance studies of gangliosides by Harris, Patricia L, Thornton, Edward R

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Alabama: Multi-library automation and connectivity initiatives by Harris, Patricia L.

“…There are a variety of multi-library automation and connectivity initiatives in Alabama. Among these are programs of the following: the Alabama Public Library…”
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Assessing burnout: the organizational and individual perspective by Harris, P L

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Burnout in nursing administration by Harris, P L

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Communication disorders: speech therapy in the home by Harris, P L

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Al on a Summer's Day by Harris, Patricia L.

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Bromocriptine and hallucinations by Harris, P L

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