Search Results - "Harris, Michele"

Blocking CTGF/CCN2 reduces established skeletal muscle fibrosis in a rat model of overuse injury by Barbe, Mary F., Hilliard, Brendan A., Amin, Mamta, Harris, Michele Y., Hobson, Lucas J., Cruz, Geneva E., Popoff, Steven N.

“…Tissue fibrosis is a hallmark of overuse musculoskeletal injuries and contributes to functional declines. We tested whether inhibition of CCN2 (cellular…”
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Manual therapy prevents onset of nociceptor activity, sensorimotor dysfunction, and neural fibrosis induced by a volitional repetitive task by Bove, Geoffrey M., Delany, Sean P., Hobson, Lucas, Cruz, Geneva E., Harris, Michele Y., Amin, Mamta, Chapelle, Susan L., Barbe, Mary F.

“…Painful and disabling musculoskeletal disorders remain prevalent. In rats trained to perform repetitive tasks leading to signs and dysfunction similar to those…”
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Manual therapy as an effective treatment for fibrosis in a rat model of upper extremity overuse injury by Bove, Geoffrey M, Harris, Michele Y, Zhao, Huaqing, Barbe, Mary F

“…Abstract Key clinical features of carpal tunnel syndrome and other types of cumulative trauma disorders of the hand and wrist include pain and functional…”
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Manual Therapy Facilitates Homeostatic Adaptation to Bone Microstructural Declines Induced by a Rat Model of Repetitive Forceful Task by Barbe, Mary F., Amin, Mamta, Harris, Michele Y., Panibatla, Siva Tejaa, Assari, Soroush, Popoff, Steven N., Bove, Geoffrey M.

“…The effectiveness of manual therapy in reducing the catabolic effects of performing repetitive intensive force tasks on bones has not been reported. We…”
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Blocking CTGF/CCN2 reverses neural fibrosis and sensorimotor declines in a rat model of overuse‐induced median mononeuropathy by Barbe, Mary F., Hilliard, Brendan A., Amin, Mamta, Harris, Michele Y., Hobson, Lucas J., Cruz, Geneva E., Dorotan, Jocelynne T., Paul, Ryan W., Klyne, David M., Popoff, Steven N.

“…Encapsulation of median nerves is a hallmark of overuse‐induced median mononeuropathy and contributes to functional declines. We tested if an antibody against…”
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Key indicators of repetitive overuse-induced neuromuscular inflammation and fibrosis are prevented by manual therapy in a rat model by Barbe, Mary F, Harris, Michele Y, Cruz, Geneva E, Amin, Mamta, Billett, Nathan M, Dorotan, Jocelynne T, Day, Emily P, Kim, Seung Y, Bove, Geoffrey M

“…We examined the effectiveness of a manual therapy consisting of forearm skin rolling, muscle mobilization, and upper extremity traction as a preventive…”
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Blocking CCN2 Reduces Progression of Sensorimotor Declines and Fibrosis in a Rat Model of Chronic Repetitive Overuse by Barbe, Mary F., Hilliard, Brendan A., Delany, Sean P., Iannarone, Victoria J., Harris, Michele Y., Amin, Mamta, Cruz, Geneva E., Barreto‐Cruz, Yeidaliz, Tran, Ngih,  Day, Emily P., Hobson, Lucas J., Assari, Soroush, Popoff, Steven N.

“…ABSTRACT Fibrosis may be a key factor in sensorimotor dysfunction in patients with chronic overuse‐induced musculoskeletal disorders. Using a clinically…”
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Manual Therapy With Rest as a Treatment for Established Inflammation and Fibrosis in a Rat Model of Repetitive Strain Injury by Barbe, Mary F., Panibatla, Siva Tejaa, Harris, Michele Y., Amin, Mamta, Dorotan, Jocelynne T., Cruz, Geneva E., Bove, Geoffrey M.

“…Background : Repetitive strain injuries caused by repetitive occupational work are difficult to prevent for multiple reasons. Therefore, we examined the…”
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Prolonged high force high repetition pulling induces osteocyte apoptosis and trabecular bone loss in distal radius, while low force high repetition pulling induces bone anabolism by Barbe, Mary F., Massicotte, Vicky S., Assari, Soroush, Monroy, M. Alexandra, Frara, Nagat, Harris, Michele Y., Amin, Mamta, King, Tamara, Cruz, Geneva E., Popoff, Steve N.

“…We have an operant rat model of upper extremity reaching and grasping in which we examined the impact of performing a high force high repetition (High-ForceHR)…”
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Design of a Robust Undergraduate Biochemistry Laboratory Module Based on a Purification Scheme for Bovine Serum Albumin by Odunuga, Odutayo O, Cheatwood, Nicholas Y, Mullins, John A, Nguyen, Samantha K, Fry, Darrell R, Harris, Michele R

“…This paper describes an undergraduate biochemistry laboratory module consisting of a set of experiments designed around a purification scheme for bovine serum…”
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Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response by Steen, Håkan C, Kotredes, Kevin P, Nogusa, Shoko, Harris, Michele Y, Balachandran, Siddharth, Gamero, Ana M

“…Serine phosphorylation of STAT proteins is an important post-translational modification event that, in addition to tyrosine phosphorylation, is required for…”
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Blocking CCN2 Reduces Established Bone Loss Induced by Prolonged Intense Loading by Increasing Osteoblast Activity in Rats by Lambi, Alex G, Harris, Michele Y, Amin, Mamta, Joiner, Patrice G, Hilliard, Brendan A, Assari, Soroush, Popoff, Steven N, Barbe, Mary F

“…We have an operant model of reaching and grasping in which detrimental bone remodeling is observed rather than beneficial adaptation when rats perform a…”
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YAP/TAZ initiate and maintain Schwann cell myelination by Grove, Matthew, Kim, Hyukmin, Santerre, Maryline, Krupka, Alexander J, Han, Seung Baek, Zhai, Jinbin, Cho, Jennifer Y, Park, Raehee, Harris, Michele, Kim, Seonhee, Sawaya, Bassel E, Kang, Shin H, Barbe, Mary F, Cho, Seo-Hee, Lemay, Michel A, Son, Young-Jin

“…Nuclear exclusion of the transcriptional regulators and potent oncoproteins, YAP/TAZ, is considered necessary for adult tissue homeostasis. Here we show that…”
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Prolonged performance of a high repetition low force task induces bone adaptation in young adult rats, but loss in mature rats by Massicotte, Vicky S., Frara, Nagat, Harris, Michele Y., Amin, Mamta, Wade, Christine K., Popoff, Steven N., Barbe, Mary F.

“…We have shown that prolonged repetitive reaching and grasping tasks lead to exposure-dependent changes in bone microarchitecture and inflammatory cytokines in…”
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Poor sleep versus exercise: A duel to decide whether pain resolves or persists after injury by Klyne, David M, Hilliard, Brendan A, Harris, Michele Y, Amin, Mamta, Hall, Michelle, Besomi, Manuela, Mustafa, Sanam, Farrell, Scott F, Rawashdeh, Oliver, Han, Felicity Y, Hodges, Paul W, Frara, Nagat, Barbe, Mary F

“…Poor sleep is thought to enhance pain via increasing peripheral and/or central sensitization. Aerobic exercise, conversely, relives pain via reducing…”
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Characterization of pain-related behaviors in a rat model of acute-to-chronic low back pain: single vs. multi-level disc injury by Barbe, Mary F, Chen, Frank Liu, Loomis, Regina H, Harris, Michele Y, Kim, Brandon M, Xie, Kevin, Hilliard, Brendan A, McGonagle, Elizabeth R, Bailey, Taylor D, Gares, Ryan P, Van Der Bas, Megan, Kalicharan, Betsy A, Holt-Bright, Lewis, Stone, Laura S, Hodges, Paul W, Klyne, David M

“…Low back pain is the most common type of chronic pain. We examined pain-related behaviors across 18 weeks in rats that received injury to one or two lumbar…”
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Improved Functional Group Compatibility in the Palladium-Catalyzed Synthesis of Aryl Amines by Harris, Michele C, Huang, Xiaohua, Buchwald, Stephen L

“…The use of Pd2dba3 with bulky, electron-rich ligands 1 or 2 and LiN(TMS)2 as the base for the coupling of amines with aryl halides containing hydroxyl, amide,…”
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Callosal disconnection neglect: reassessment after 34 years by Good, Allison J., Harris, Michele K., Falchook, Adam D., Watson, Robert T., Heilman, Kenneth M.

“…In 1984, Watson and Heilman reported a patient with a partial callosal disconnection following an infarction of the anterior portion of her corpus callosum…”
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Efficient Palladium-Catalyzed N-Arylation of Indoles by Old, David W, Harris, Michele C, Buchwald, Stephen L

“…The N-arylation of indoles, including a variety of substituted ones, has been carried out using bulky, electron-rich phosphines as the supporting ligand in…”
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One-Pot Synthesis of Unsymmetrical Triarylamines from Aniline Precursors by Harris, Michele C, Buchwald, Stephen L

“…The “one-pot” synthesis of triarylamines from an aniline and two different aryl halides is described. A catalytic system composed of…”
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