Search Results - "Harris, Melissa G"

CCR7 deficient inflammatory Dendritic Cells are retained in the Central Nervous System by Clarkson, Benjamin D., Walker, Alec, Harris, Melissa G., Rayasam, Aditya, Hsu, Martin, Sandor, Matyas, Fabry, Zsuzsanna

“…Dendritic cells (DC) accumulate in the CNS during neuroinflammation, yet, how these cells contribute to CNS antigen drainage is still unknown. We have…”
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Deletion of mitochondrial anchoring protects dysmyelinating shiverer: implications for progressive MS by Joshi, Dinesh C, Zhang, Chuan-Li, Lin, Tien-Min, Gusain, Anchal, Harris, Melissa G, Tree, Esther, Yin, Yewin, Wu, Connie, Sheng, Zu-Hang, Dempsey, Robert J, Fabry, Zsuzsanna, Chiu, Shing Yan

“…The demyelinating disease multiple sclerosis (MS) has an early inflammatory phase followed by an incurable progressive phase with subdued inflammation and…”
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CCR2-dependent dendritic cell accumulation in the central nervous system during early effector experimental autoimmune encephalomyelitis is essential for effector T cell restimulation in situ and disease progression by Clarkson, Benjamin D, Walker, Alec, Harris, Melissa G, Rayasam, Aditya, Sandor, Matyas, Fabry, Zsuzsanna

“…Dendritic cells (DCs)--although absent from the healthy CNS parenchyma--rapidly accumulate within brain and spinal cord tissue during neuroinflammation…”
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T cell-derived interleukin (IL)-21 promotes brain injury following stroke in mice by Clarkson, Benjamin D S, Ling, Changying, Shi, Yejie, Harris, Melissa G, Rayasam, Aditya, Sun, Dandan, Salamat, M Shahriar, Kuchroo, Vijay, Lambris, John D, Sandor, Matyas, Fabry, Zsuzsanna

“…T lymphocytes are key contributors to the acute phase of cerebral ischemia reperfusion injury, but the relevant T cell-derived mediators of tissue injury…”
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Immune privilege of the CNS is not the consequence of limited antigen sampling by Harris, Melissa G., Hulseberg, Paul, Ling, Changying, Karman, Jozsef, Clarkson, Benjamin D., Harding, Jeffrey S., Zhang, Mengxue, Sandor, Adam, Christensen, Kelsey, Nagy, Andras, Sandor, Matyas, Fabry, Zsuzsanna

“…Central nervous system (CNS) immune privilege is complex and it is still not understood how CNS antigens are sampled by the peripheral immune system under…”
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Regional Distribution of CNS Antigens Differentially Determines T-Cell Mediated Neuroinflammation in a CX3CR1-Dependent Manner by Rayasam, Aditya, Kijak, Julie A, Dallmann, McKenna, Hsu, Martin, Zindl, Nicole, Lindstedt, Anders, Steinmetz, Leah, Harding, Jeffrey S, Harris, Melissa G, Karman, Jozsef, Sandor, Matyas, Fabry, Zsuzsanna

“…T cells continuously sample CNS-derived antigens in the periphery, yet it is unknown how they sample and respond to CNS antigens derived from distinct brain…”
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Innate-adaptive crosstalk: how dendritic cells shape immune responses in the CNS by Clarkson, Benjamin D, Héninger, Erika, Harris, Melissa G, Lee, JangEun, Sandor, Matyas, Fabry, Zsuzsanna

“…Dendritic cells (DCs) are a heterogeneous group of professional antigen presenting cells that lie in a nexus between innate and adaptive immunity because they…”
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Sensing the microenvironment of the central nervous system: immune cells in the central nervous system and their pharmacological manipulation by Fabry, Zsuzsanna, Schreiber, Heidi A, Harris, Melissa G, Sandor, Matyas

“…Immune responses are highly regulated in all organs and severely restricted in certain tissues within the central nervous system (CNS). This phenomenon, called…”
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CCR2-dependent dendritic cell accumulation in CNS during early effector EAE is essential for effector T cell restimulation in situ and disease progression by Clarkson, Benjamin D, Walker, Alec, Harris, Melissa G., Rayasam, Aditya, Sandor, Matyas, Fabry, Zsuzsanna

“…Dendritic cells (DCs)—while absent from the healthy CNS parenchyma—rapidly accumulate within brain and spinal cord tissue during neuroinflammation associated…”
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Immune surveillance of the central nervous system during experimental autoimmune encephalomyelitis by Harris, Melissa G

“…For a long time the central nervous system (CNS) was considered to be immune privileged tissue, in which it was believed to be completely disconnected from…”
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